Global effect of RpoS on gene expression in pathogenic Escherichia coliO157:H7 strain EDL933 (2009)
Abstract Background RpoS is a conserved stress regulator that plays a critical role in survival under stress conditions in Escherichia coli and other γ-proteobacteria. RpoS is also involved in...
Phenotypic characterization of HIV-specific CD8 T cells during acute infant HIV infection (2009)
Slyker, Jennifer, Dong, Tao, John-Stewart, Grace, Lohman-Payne, Barbara, Reilly, Marie, Atzberger, Ann, ...
No abstract available.
Polymorphism and selection of rpoSin pathogenic Escherichia coli (2009)
Dong, Tao, Chiang, Sarah M, Joyce, Charlie, Yu, Rosemary, Schellhorn, Herb E
Abstract Background Though RpoS is important for survival of pathogenic Escherichia coli in natural environments, polymorphism in the rpoS gene is common. However, the causes of this polymorphism and...
Yaohang Li, Tao Dong, Marwan Bikdash, Yong Duan Song
One of the main objectives when planning paths for unmanned vehicles is to minimizing the time of arriving at the given destination while maximizing the safety of the vehicles. If the operational...
Primary CMV infection: a co-factor HIV-1 disease progression in African infants? (2008)
Slyker, Jennifer A, Payne, Barbara L, John-Stewart, Grace C, Obimbo, Elizabeth, Emery, Sandy, Richardson, Barbara, ...
No abstract available.
HIV-2 gene product-specific T cell responses and viraemia control (2006)
Leligdowicz, Aleksandra, Yindom, Louis-Marie, Jaye, Assan, Dong, Tao, Alabi, Abraham, Sarge-N'jie, Ramu, ...
No abstract available.
Ondondo, Beatrice, Yang, Hongbing, Dong, Tao, Gleria, Kati De, Suttill, Annie, Conlon, Christopher, ...
No abstract available.
Stationary phase expression of the arginine biosynthetic operon argCBHin Escherichia coli (2006)
Weerasinghe, Jeevaka P, Dong, Tao, Schertzberg, Michael R, Kirchhof, Mark G, Sun, Yuan, Schellhorn, Herb E
Abstract Background Arginine biosynthesis in Escherichia coli is elevated in response to nutrient limitation, stress or arginine restriction. Though control of the pathway in response to arginine...
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection (2004)
Laura Papagno, Celsa A. Spina, Arnaud Marchant, Mariolina Salio, Nathalie Rufer, Susan Little, ...
HIV-1 infection induces activation and differentiation of CD8+ T-cells, resulting in replicative senescence. This may be part of the mechanism through which HIV-1 exhausts the capacity of the immune...
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection (2004)
Laura Papagno, Celsa A. Spina, Arnaud Marchant, Mariolina Salio, Nathalie Rufer, Susan Little, ...
Progress in the fight against the HIV/AIDS epidemic is hindered by our failure to elucidate the precise reasons for the onset of immunodeficiency in HIV-1 infection. Increasing evidence suggests that...
Includes reprints of two published papers at the end of the work.
Stationary phase expression of the arginine biosynthetic operon argCBH in Escherichia coli
Weerasinghe, Jeevaka P, Dong, Tao, Schertzberg, Michael R, Kirchhof, Mark G, Sun, Yuan, Schellhorn, Herb E
Dorrell, Lucy, Dong, Tao, Ogg, Graham S., Lister, Simon, McAdam, Steve, Rostron, Tim, ...
We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several...
John, Grace C., Rousseau, Christine, Dong, Tao, Rowland-Jones, Sarah, Nduati, Ruth, Mbori-Ngacha, Dorothy, ...
Genetic polymorphisms in chemokine and chemokine receptor genes influence susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and disease progression, but little is known...
Kaul, Rupert, Rowland-Jones, Sarah L., Kimani, Joshua, Dong, Tao, Yang, Hong-Bing, Kiama, Peter, ...
Resistance to HIV infection in a small group of Kenyan sex workers is associated with CD8+-lymphocyte responses to HIV cytotoxic T-lymphocyte (CTL) epitopes. Eleven prostitutes meeting criteria for...
CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjects
Kaul, Rupert, Dong, Tao, Plummer, Francis A., Kimani, Joshua, Rostron, Timothy, Kiama, Peter, ...
HIV-1–specific cytotoxic T-lymphocyte (CTL) responses have been detected at a low frequency in many HIV-1–exposed, persistently seronegative (HEPS) subjects. However, it is unclear how CTLs could...
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection
Papagno, Laura, Spina, Celsa A, Marchant, Arnaud, Salio, Mariolina, Rufer, Nathalie, Little, Susan, ...
Progress in the fight against the HIV/AIDS epidemic is hindered by our failure to elucidate the precise reasons for the onset of immunodeficiency in HIV-1 infection. Increasing evidence suggests that...
Simmons, Cameron P., Dong, Tao, Chau, Nguyen Vinh, Dung, Nguyen Thi Phuong, Chau, Tran Nguyen Bich, Thao, Le Thi Thu, ...
T-cell responses to dengue viruses may be important in both protective immunity and pathogenesis. This study of 48 Vietnamese adults with secondary dengue virus infections defined the breadth and...
Lohman, Barbara L., Slyker, Jennifer A., Richardson, Barbra A., Farquhar, Carey, Mabuka, Jenniffer M., Crudder, Christopher, ...
Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in...
Dorrell, Lucy, Yang, Hongbing, Ondondo, Beatrice, Dong, Tao, Di Gleria, Kati, Suttill, Annie, ...
Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. Since CD8+ and...
Dorrell, Lucy, Dong, Tao, Ogg, Graham S., Lister, Simon, McAdam, Steve, Rostron, Tim, ...
We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several...
John, Grace C., Rousseau, Christine, Dong, Tao, Rowland-Jones, Sarah, Nduati, Ruth, Mbori-Ngacha, Dorothy, ...
Genetic polymorphisms in chemokine and chemokine receptor genes influence susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and disease progression, but little is known...
Kaul, Rupert, Rowland-Jones, Sarah L., Kimani, Joshua, Dong, Tao, Yang, Hong-Bing, Kiama, Peter, ...
Resistance to HIV infection in a small group of Kenyan sex workers is associated with CD8+-lymphocyte responses to HIV cytotoxic T-lymphocyte (CTL) epitopes. Eleven prostitutes meeting criteria for...
CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjects
Kaul, Rupert, Dong, Tao, Plummer, Francis A., Kimani, Joshua, Rostron, Timothy, Kiama, Peter, ...
HIV-1–specific cytotoxic T-lymphocyte (CTL) responses have been detected at a low frequency in many HIV-1–exposed, persistently seronegative (HEPS) subjects. However, it is unclear how CTLs could...
Immune Activation and CD8+ T-Cell Differentiation towards Senescence in HIV-1 Infection
Papagno, Laura, Spina, Celsa A, Marchant, Arnaud, Salio, Mariolina, Rufer, Nathalie, Little, Susan, ...
Progress in the fight against the HIV/AIDS epidemic is hindered by our failure to elucidate the precise reasons for the onset of immunodeficiency in HIV-1 infection. Increasing evidence suggests that...
Simmons, Cameron P., Dong, Tao, Chau, Nguyen Vinh, Dung, Nguyen Thi Phuong, Chau, Tran Nguyen Bich, Thao, Le Thi Thu, ...
T-cell responses to dengue viruses may be important in both protective immunity and pathogenesis. This study of 48 Vietnamese adults with secondary dengue virus infections defined the breadth and...
Lohman, Barbara L., Slyker, Jennifer A., Richardson, Barbra A., Farquhar, Carey, Mabuka, Jenniffer M., Crudder, Christopher, ...
Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in...
Stationary phase expression of the arginine biosynthetic operon argCBH in Escherichia coli
Weerasinghe, Jeevaka P, Dong, Tao, Schertzberg, Michael R, Kirchhof, Mark G, Sun, Yuan, Schellhorn, Herb E
Dorrell, Lucy, Yang, Hongbing, Ondondo, Beatrice, Dong, Tao, Di Gleria, Kati, Suttill, Annie, ...
Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. Since CD8+ and...
HIV-2 gene product-specific T cell responses and viraemia control
Leligdowicz, Aleksandra, Yindom, Louis-Marie, Jaye, Assan, Dong, Tao, Alabi, Abraham, Sarge-N'jie, Ramu, ...
Ondondo, Beatrice, Yang, Hongbing, Dong, Tao, Gleria, Kati De, Suttill, Annie, Conlon, Christopher, ...
Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine
Létourneau, Sven, Im, Eung-Jun, Mashishi, Tumelo, Brereton, Choechoe, Bridgeman, Anne, Yang, Hongbing, ...
Robust Gag-specific T cell responses characterize viremia control in HIV-2 infection
Leligdowicz, Aleksandra, Yindom, Louis-Marie, Onyango, Clayton, Sarge-Njie, Ramu, Alabi, Abraham, Cotten, Matthew, ...
HIV-2 infection in the majority of infected subjects follows an attenuated disease course that distinguishes it from infection with HIV-1. Antigen-specific T cells are pivotal in the management of...
Increased frequencies of CD4+CD25high regulatory T cells in acute dengue infection
Lühn, Kerstin, Simmons, Cameron P., Moran, Edward, Dung, Nguyen Thi Phuong, Chau, Tran Nguyen Bich, Quyen, Nguyen Than Ha, ...
Dengue virus infection is an increasingly important tropical disease, causing 100 million cases each year. Symptoms range from mild febrile illness to severe hemorrhagic fever. The pathogenesis is...
T Cell Cross-Reactivity and Conformational Changes during TCR Engagement
Lee, Jean K., Stewart-Jones, Guillaume, Dong, Tao, Harlos, Karl, Di Gleria, Kati, Dorrell, Lucy, ...
All thymically selected T cells are inherently cross-reactive, yet many data indicate a fine specificity in antigen recognition, which enables virus escape from immune control by mutation in...
HIV-specific Cytotoxic T Cells from Long-Term Survivors Select a Unique T Cell Receptor
Dong, Tao, Stewart-Jones, Guillaume, Chen, Nan, Easterbrook, Philippa, Xu, Xiaoning, Papagno, Laura, ...
HIV-specific cytotoxic T lymphocytes (CTL) are important in controlling HIV replication, but the magnitude of the CTL response does not predict clinical outcome. In four donors with delayed disease...
HIV-Specific Cd8+ T Cells Produce Antiviral Cytokines but Are Impaired in Cytolytic Function
Appay, Victor, Nixon, Douglas F., Donahoe, Sean M., Gillespie, Geraldine M.A., Dong, Tao, King, Abigail, ...
The use of peptide–human histocompatibility leukocyte antigen (HLA) class I tetrameric complexes to identify antigen-specific CD8+ T cells has provided a major development in our understanding of...
Xu, Xiao-Ning, Screaton, Gavin R., Gotch, Frances M., Dong, Tao, Tan, Rusung, Almond, Neil, ...
Inoculation of macaques with live attenuated SIV strains has been shown to protect against subsequent challenge with wild-type SIV. The protective mechanism(s) remain obscure. To study the effect in...
Lee, Laurel Yong-Hwa, Ha, Do Lien Anh, Simmons, Cameron, De Jong, Menno D., Chau, Nguyen Van Vinh, Schumacher, Reto, ...
The threat of avian influenza A (H5N1) infection in humans remains a global health concern. Current influenza vaccines stimulate antibody responses against the surface glycoproteins but are...
De Santo, Carmela, Salio, Mariolina, Masri, S. Hajar, Lee, Laurel Yong-Hwa, Dong, Tao, Speak, Anneliese O., ...
Infection with influenza A virus (IAV) presents a substantial threat to public health worldwide, with young, elderly, and immunodeficient individuals being particularly susceptible. Inflammatory...
Polymorphism and selection of rpoS in pathogenic Escherichia coli
Dong, Tao, Chiang, Sarah M, Joyce, Charlie, Yu, Rosemary, Schellhorn, Herb E
Role of RpoS in the Virulence of Citrobacter rodentium▿
Dong, Tao, Coombes, Brian K., Schellhorn, Herb E.
Citrobacter rodentium is a mouse enteropathogen that is closely related to Escherichia coli and causes severe colonic hyperplasia and bloody diarrhea. C. rodentium infection requires expression of...
Choudhuri, Kaushik, Parker, Mathew, Milicic, Anita, Cole, David K., Shaw, Michael K., Sewell, Andrew K., ...
T cell antigen recognition requires binding of the T cell receptor (TCR) to a complex between peptide antigen and major histocompatibility complex molecules (pMHC), and this recognition occurs at the...