Tatyana Chanturiya

Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity

Guo, Tingqing, Jou, William, Chanturiya, Tatyana, Portas, Jennifer, Gavrilova, Oksana, McPherron, Alexandra C.

Myostatin (Mstn) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Mstn−/− mice have a dramatic increase in muscle mass,...