Burton, Paul R, Hansell, Anna L, Fortier, Isabel, Manolio, Teri A, Khoury, Muin J, Little, Julian, ...
Background Despite earlier doubts, a string of recent successes indicates that if sample sizes are large enough, it is possible—both in theory and in practice—to identify and replicate genetic...
The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine (2009)
Biesecker, Leslie G., Mullikin, James C., Facio, Flavia M., Turner, Clesson, Cherukuri, Praveen F., Blakesley, Robert W., ...
ClinSeq is a pilot project to investigate the use of whole-genome sequencing as a tool for clinical research. By piloting the acquisition of large amounts of DNA sequence data from individual human...
Higgins, Julian P. T., Little, Julian, Ioannidis, John P. A., Bray, Molly S., Manolio, Teri A., Smeeth, Liam, ...
Longstreth, WT, Larsen, Emily K. Marino, Klein, Ronald, Wong, Tien Yin, Sharrett, A. Richey, Lefkowitz, David, ...
Associations between findings on cranial magnetic resonance imaging (MRI) and retinal photographs have been described mostly in middle-aged people. In the Cardiovascular Health Study, 1,717 elderly...
Foppa, Murilo, Duncan, Bruce B, Arnett, Donna K, Benjamin, Emelia J, Liebson, Philip R, Manolio, Teri A, ...
Abstract Background Cardiovascular risk associated with diabetes may be partially attributed to left ventricular structural abnormalities. However, the relations between left ventricular structure...
Familial aggregation of atrial fibrillation in Iceland (2006)
Arnar, David O, Thorvaldsson, Sverrir, Manolio, Teri A, Thorgeirsson, Gudmundur, Kristjansson, Kristleifur, Hakonarson, Hakon, ...
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Familial aggregation of atrial fibrillation in Iceland (2006)
Arnar, David O., Thorvaldsson, Sverrir, Manolio, Teri A., Thorgeirsson, Gudmundur, Kristjansson, Kristleifur, Hakonarson, Hakon, ...
Aims To examine the heritability of atrial fibrillation (AF) in Icelanders, utilizing a nationwide genealogy database and population-based data on AF. AF is a disorder with a high prevalence, which...
Familial aggregation of atrial fibrillation in Iceland (2006)
Arnar, David O., Thorvaldsson, Sverrir, Manolio, Teri A., Thorgeirsson, Gudmundur, Kristjansson, Kristleifur, Hakonarson, Hakon, ...
Aims To examine the heritability of atrial fibrillation (AF) in Icelanders, utilizing a nationwide genealogy database and population-based data on AF. AF is a disorder with a high prevalence, which...
Obtaining Informed Consent for Genetic Studies: The Multiethnic Study of Atherosclerosis (2006)
Green, David, Cushman, Mary, Dermond, Norma, Johnson, Eric A., Castro, Cecilia, Arnett, Donna, ...
Studies of DNA may yield important information about atherosclerosis. To determine how often study participants' consent to examine DNA is denied and the factors associated with that denial,...
Pajak, Andrzej, Broda, Grazyna, Manolio, Teri A, Kawalec, Ewa, Rywik, Stefan, Davis, CE, ...
Background Fibrinogen and factor VII activity are known to be related to atherosclerosis and coronary heart disease, but population differences in dotting factors and modifiable characteristics that...
Hostility and Health Behaviors in Young Adults: The CARDIA Study (1992)
Scherwitz, Larry W., Perkins, Laura L, Chesrtey, Margaret A., Hughes, Glenn H., Sidney, Stephen, Manolio, Teri A.
Hostility has been associated with coronary heart disease mortality. To assess possible mechanisms linking hostility to coronary heart disease risk, the authors conducted analyses in a...
Fish Consumption and Stroke Risk in Elderly Individuals: The Cardiovascular Health Study
Mozaffarian, Dariush, Longstreth, W. T., Lemaitre, Rozenn N., Manolio, Teri A., Kuller, Lewis H., Burke, Gregory L., ...
Foppa, Murilo, Duncan, Bruce B, Arnett, Donna K, Benjamin, Emelia J, Liebson, Philip R, Manolio, Teri A, ...
Foppa, Murilo, Duncan, Bruce B, Arnett, Donna K, Benjamin, Emelia J, Liebson, Philip R, Manolio, Teri A, ...
A HapMap harvest of insights into the genetics of common disease
Manolio, Teri A., Brooks, Lisa D., Collins, Francis S.
The International HapMap Project was designed to create a genome-wide database of patterns of human genetic variation, with the expectation that these patterns would be useful for genetic association...
Burton, Paul R, Hansell, Anna L, Fortier, Isabel, Manolio, Teri A, Khoury, Muin J, Little, Julian, ...
Background Despite earlier doubts, a string of recent successes indicates that if sample sizes are large enough, it is possible—both in theory and in practice—to identify and replicate genetic...
Hindorff, Lucia A., Sethupathy, Praveen, Junkins, Heather A., Ramos, Erin M., Mehta, Jayashri P., Collins, Francis S., ...
We have developed an online catalog of SNP-trait associations from published genome-wide association studies for use in investigating genomic characteristics of trait/disease-associated SNPs (TASs)....