Tetsuyuki Kitamoto

A Japanese family with a variant of Gerstmann-Straussler-Scheinker disease (1997)

Tanaka, Yutaka, Minematsu, Kazuo, Moriyasu, Hideki, Yamaguchi, Takenori, Yutani, Chikao, Kitamoto, Tetsuyuki, ...

OBJECTIVE: A new variant of Gerstmann-Straussler-Scheinker disease (GSS) was reported, which had a substitution of glutamate to lysine at codon 219 (E219K) in addition to a P102L mutation on the same...

An Exon 8-Spliced Out Transcript of Neurofibromatosis 2 Gene Is Constitutively Expressed in Various Human Tissues (1994)

Hitotsumatsu, Tsutomu, Kitamoto, Tetsuyuki, Iwaki, Toru, Fukui, Masashi, Tateishi, Jun

We succeeded in cloning the exon 8-spliced out transcript of neurofibromatosis 2 (NF2) gene in human glioma cell lines. We then investigated the expression of the spliced out form in various human...

Immunohistochemical quantification of substance P in spinal dorsal horns of patients with multiple system atrophy (1991)

Tomokane, Naoyuki, Kitamoto, Tetsuyuki, Tateishi, Jun, Sato, Yuji, 北本, 哲之, 立石, 潤, ...

Using a computer-assisted image analyser, an immunohistochemical quantification method of substance P-like immunoreactivity (SPLI) in laminae I + II of spinal dorsal horn was established and applied...

Species Barrier Prevents an Abnormal Isoform of Prion Protein from Accumulating in Follicular Dendritic Cells of Mice with Creutzfeldt-Jakob Disease

Muramoto, Tamaki, Kitamoto, Tetsuyuki, Hoque, Mohammad Zahirul, Tateishi, Jun, Goto, Ikuo

The accumulation of abnormal prion protein in follicular dendritic cells did not occur in mice inoculated with materials from human Creutzfeldt-Jakob disease, whereas it always occurred in mice...

Species Barrier Prevents an Abnormal Isoform of Prion Protein from Accumulating in Follicular Dendritic Cells of Mice with Creutzfeldt-Jakob Disease

Muramoto, Tamaki, Kitamoto, Tetsuyuki, Hoque, Mohammad Zahirul, Tateishi, Jun, Goto, Ikuo

The accumulation of abnormal prion protein in follicular dendritic cells did not occur in mice inoculated with materials from human Creutzfeldt-Jakob disease, whereas it always occurred in mice...

Interaction of Aluminum with PHFτ in Alzheimer’s Disease Neurofibrillary Degeneration Evidenced by Desferrioxamine-Assisted Chelating Autoclave Method

Murayama, Harunobu, Shin, Ryong-Woon, Higuchi, Jun, Shibuya, Satoshi, Muramoto, Tamaki, Kitamoto, Tetsuyuki

To demonstrate that aluminum III (Al) interacts with PHFτ in neurofibrillary degeneration (NFD) of Alzheimer’s disease (AD) brain, we developed a “chelating autoclave method” that allows Al...

Humanized Knock-In Mice Expressing Chimeric Prion Protein Showed Varied Susceptibility to Different Human Prions

Taguchi, Yuzuru, Mohri, Shirou, Ironside, James W., Muramoto, Tamaki, Kitamoto, Tetsuyuki

Mice to which human prions efficiently transmit in short incubation periods are valuable not only as research tools of human prions but also as reliable diagnostic tools. We recently produced a line...

Ophthalmic Surgery in Prion Diseases

Hamaguchi, Tsuyoshi, Noguchi-Shinohara, Moeko, Nakamura, Yosikazu, Sato, Takeshi, Kitamoto, Tetsuyuki, Mizusawa, Hidehiro, ...

Eleven (1.8%) of 597 patients underwent ophthalmic surgery within 1 month before the onset of prion disease or after the onset. All ophthalmologists reused surgical instruments that had been...