Theresa J. Goletz

Molecular Alterations in Pediatric Sarcomas: Potential Targets for Immunotherapy (1998)

Theresa J. Goletz, Crystal L. Mackall, Jay A. Berzofsky, Lee J. Helman

Purpose/results/discussion. Recurrent chromosomal translocations are common features of many human malignancies. While such translocations often serve as diagnostic markers, molecular analysis of...

Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine

Bronte, Vincenzo, Carroll, Miles W., Goletz, Theresa J., Wang, Michael, Overwijk, Willem W., Marincola, Francesco, ...

Recombinant poxviruses encoding tumor-associated antigens (TAA) are attractive as candidate cancer vaccines. Their effectiveness, however, will depend upon expression of the TAA in appropriate...

Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein

Goletz, Theresa J., Klimpel, Kurt R., Arora, Naveen, Leppla, Stephen H., Keith, Jerry M., Berzofsky, Jay A.

A challenge for subunit vaccines whose goal is to elicit CD8+ cytotoxic T lymphocytes (CTLs) is to deliver the antigen to the cytosol of the living cell, where it can be processed for presentation by...

Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine

Bronte, Vincenzo, Carroll, Miles W., Goletz, Theresa J., Wang, Michael, Overwijk, Willem W., Marincola, Francesco, ...

Recombinant poxviruses encoding tumor-associated antigens (TAA) are attractive as candidate cancer vaccines. Their effectiveness, however, will depend upon expression of the TAA in appropriate...

Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein

Goletz, Theresa J., Klimpel, Kurt R., Arora, Naveen, Leppla, Stephen H., Keith, Jerry M., Berzofsky, Jay A.

A challenge for subunit vaccines whose goal is to elicit CD8+ cytotoxic T lymphocytes (CTLs) is to deliver the antigen to the cytosol of the living cell, where it can be processed for presentation by...

gp100/pmel 17 Is a Murine Tumor Rejection Antigen: Induction of “Self”-reactive, Tumoricidal T Cells Using High-affinity, Altered Peptide Ligand

Overwijk, Willem W., Tsung, Allan, Irvine, Kari R., Parkhurst, Maria R., Goletz, Theresa J., Tsung, Kangla, ...

Many tumor-associated antigens are nonmutated, poorly immunogenic tissue differentiation antigens. Their weak immunogenicity may be due to “self”-tolerance. To induce autoreactive T cells, we...

Molecular Alterations in Pediatric Sarcomas: Potential Targets for Immunotherapy

Goletz, Theresa J., Mackall, Crystal L., Berzofsky, Jay A., Helman, Lee J.

Purpose/results/discussion. Recurrent chromosomal translocations are common features of many human malignancies. While such translocations often serve as diagnostic markers, molecular analysis of...