Thierry Soldati

Dual Targeting of Antioxidant and Metabolic Enzymes to the Mitochondrion and the Apicoplast of Toxoplasma gondii (2007)

Paco Pino, Bernardo Javier Foth, Lai-Yu Kwok, Lilach Sheiner, Rebecca Schepers, Thierry Soldati, ...

Toxoplasma gondii is an aerobic protozoan parasite that possesses mitochondrial antioxidant enzymes to safely dispose of oxygen radicals generated by cellular respiration and metabolism. As with most...

High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases (2002)

Gotthardt,Daniel, Warnatz,Hans Jörg, Henschel,Oliver, Brückert,Franz, Schleicher,Michael, Soldati,Thierry

Molecular mechanisms of endocytosis in the genetically and biochemically tractable professional phagocyte Dictyostelium discoideum reveal a striking degree of similarity to higher eukaryotic cells....

Morpholgy and dynamcis of the endocytic pathway in Dictyostelium discoideum (2002)

Neuhaus,Eva M., Almers,Wolfhardt, Soldati,Thierry

Dictyostelium discoideum is a genetically and biochemically tractable social amoeba belonging to the crown group of eukaryotes. It performs some of the tasks characteristic of a leukocyte such as...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz,Angelika, Weiss,Stefan, Stratmann,Rolf, Fujita-Becker,Setsuko, Ruff,Christine, Meyhöfer,Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz,Angelika, Weiss,Stefan, Stratmann,Rolf, Fujita-Becker,Setsuko, Ruff,Christine, Meyhöfer,Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases (2002)

Gotthardt, Daniel, Warnatz, Hans Jörg, Henschel, Oliver, Brückert, Franz, Schleicher, Michael, Soldati, Thierry

Molecular mechanisms of endocytosis in the genetically and biochemically tractable professional phagocyte Dictyostelium discoideum reveal a striking degree of similarity to higher eukaryotic cells....

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plusend directed motor (2002)

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

Morpholgy and dynamcis of the endocytic pathway in Dictyostelium discoideum (2002)

Neuhaus, Eva M., Almers, Wolfhardt, Soldati, Thierry

Dictyostelium discoideum is a genetically and biochemically tractable social amoeba belonging to the crown group of eukaryotes. It performs some of the tasks characteristic of a leukocyte such as...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac,Frédéric, Sänger,Astrid, Neuhaus,Eva M., Stratmann,Rolf, Ajioka,James W., Toursel,Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac,Frédéric, Sänger,Astrid, Neuhaus,Eva M., Stratmann,Rolf, Ajioka,James W., Toursel,Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations and a role in parasite division (2001)

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...

Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase (2000)

Monnat,Jean, Neuhaus,Eva M., Pop,Marius S., Ferrari,David M., Kramer,Barbara, Soldati,Thierry

Localization of soluble endoplasmic reticulum (ER) resident proteins is likely achieved by the complementary action of retrieval and retention mechanisms. Whereas the machinery involving the H/KDEL...

Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase (2000)

Monnat,Jean, Neuhaus,Eva M., Pop,Marius S., Ferrari,David M., Kramer,Barbara, Soldati,Thierry

Localization of soluble endoplasmic reticulum (ER) resident proteins is likely achieved by the complementary action of retrieval and retention mechanisms. Whereas the machinery involving the H/KDEL...

Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells (2000)

Lang,Thorsten, Wacker,Irene, Wunderlich,Ilse, Rohrbach,Alexander, Giese,Günter, Soldati,Thierry, ...

In neuroendocrine PC-12 cells, evanescent-field fluorescence microscopy was used to track motions of green fluorescent protein (GFP)-labeled actin or GFP-labeled secretory granules in a thin layer of...

Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells (2000)

Lang,Thorsten, Wacker,Irene, Wunderlich,Ilse, Rohrbach,Alexander, Giese,Günter, Soldati,Thierry, ...

In neuroendocrine PC-12 cells, evanescent-field fluorescence microscopy was used to track motions of green fluorescent protein (GFP)-labeled actin or GFP-labeled secretory granules in a thin layer of...

The tail domain of myosin M catalyses nucleotide exchange on Rac1-GTPases and can induce actin-driven surface protrusions (2000)

Geissler,Heidrun, Ullmann,Ronald, Soldati,Thierry

Members of the myosin superfamily play crucial roles in cellular processes including management of the cortical cytoskeleton, organelle transport and signal transduction. GTPases of the Rho family...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann,Christine, Herm,Angelika, Geiter,Ariane, Frank,Bernd, Schwarz,Eva C., Soldati,Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann,Christine, Herm,Angelika, Geiter,Ariane, Frank,Bernd, Schwarz,Eva C., Soldati,Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells (2000)

Lang, Thorsten, Wacker, Irene, Wunderlich, Ilse, Rohrbach, Alexander, Giese, Günter, Soldati, Thierry, ...

In neuroendocrine PC-12 cells, evanescent-field fluorescence microscopy was used to track motions of green fluorescent protein (GFP)-labeled actin or GFP-labeled secretory granules in a thin layer of...

Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase (2000)

Monnat, Jean, Neuhaus, Eva M., Pop, Marius S., Ferrari, David M., Kramer, Barbara, Soldati, Thierry

Localization of soluble endoplasmic reticulum (ER) resident proteins is likely achieved by the complementary action of retrieval and retention mechanisms. Whereas the machinery involving the H/KDEL...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva C., Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

The tail domain of myosin M catalyses nucleotide exchange on Rac1-GTPases and can induce actin-driven surface protrusions (2000)

Geissler, Heidrun, Ullmann, Ronald, Soldati, Thierry

Members of the myosin superfamily play crucial roles in cellular processes including management of the cortical cytoskeleton, organelle transport and signal transduction. GTPases of the Rho family...

Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells (2000)

Lang, Thorsten, Wacker, Irene, Wunderlich, Ilse, Rohrbach, Alexander, Giese, Günter, Soldati, Thierry, ...

In neuroendocrine PC-12 cells, evanescent-field fluorescence microscopy was used to track motions of green fluorescent protein (GFP)-labeled actin or GFP-labeled secretory granules in a thin layer of...

Identification of a novel saturable endoplasmic reticulum localization mechanism mediated by the C-terminus of a Dictyostelium protein disulfide isomerase (2000)

Monnat, Jean, Neuhaus, Eva M., Pop, Marius S., Ferrari, David M., Kramer, Barbara, Soldati, Thierry

Localization of soluble endoplasmic reticulum (ER) resident proteins is likely achieved by the complementary action of retrieval and retention mechanisms. Whereas the machinery involving the H/KDEL...

A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization (2000)

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva C., Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies (1998)

Neuhaus,Eva M., Horstmann,Heinz, Almers,Wolfhardt, Maniak,M., Soldati,Thierry

In order to dissect at the ultrastructural level the morphology of highly dynamic processes such as cell motility, membrane trafficking events, and organelle movements, it is necessary to fix/stop...

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies (1998)

Neuhaus,Eva M., Horstmann,Heinz, Almers,Wolfhardt, Maniak,M., Soldati,Thierry

In order to dissect at the ultrastructural level the morphology of highly dynamic processes such as cell motility, membrane trafficking events, and organelle movements, it is necessary to fix/stop...

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies (1998)

Neuhaus,Eva M., Horstmann,Heinz, Almers,Wolfhardt, Maniak,M., Soldati,Thierry

In order to dissect at the ultrastructural level the morphology of highly dynamic processes such as cell motility, membrane trafficking events, and organelle movements, it is necessary to fix/stop...

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies (1998)

Neuhaus, Eva M., Horstmann, Heinz, Almers, Wolfhardt, Maniak, M., Soldati, Thierry

In order to dissect at the ultrastructural level the morphology of highly dynamic processes such as cell motility, membrane trafficking events, and organelle movements, it is necessary to fix/stop...

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies (1998)

Neuhaus, Eva M., Horstmann, Heinz, Almers, Wolfhardt, Maniak, M., Soldati, Thierry

In order to dissect at the ultrastructural level the morphology of highly dynamic processes such as cell motility, membrane trafficking events, and organelle movements, it is necessary to fix/stop...

Ethane-freezing/methanol-fixation of cell monolayers: a procedure for improved preservation of structure and antigenicity for light and electron microscopies (1998)

Neuhaus, Eva M., Horstmann, Heinz, Almers, Wolfhardt, Maniak, M., Soldati, Thierry

In order to dissect at the ultrastructural level the morphology of highly dynamic processes such as cell motility, membrane trafficking events, and organelle movements, it is necessary to fix/stop...

A Dibasic Motif in the Tail of a Class XIV Apicomplexan Myosin Is an Essential Determinant of Plasma Membrane Localization

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva, Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Identification of a Novel Saturable Endoplasmic Reticulum Localization Mechanism Mediated by the C-Terminus of a Dictyostelium Protein Disulfide Isomerase

Monnat, Jean, Neuhaus, Eva M., Pop, Marius S., Ferrari, David M., Kramer, Barbara, Soldati, Thierry

Localization of soluble endoplasmic reticulum (ER) resident proteins is likely achieved by the complementary action of retrieval and retention mechanisms. Whereas the machinery involving the H/KDEL...

Morphology and Dynamics of the Endocytic Pathway in Dictyostelium discoideumV⃞

Neuhaus, Eva M., Almers, Wolfhard, Soldati, Thierry

Dictyostelium discoideum is a genetically and biochemically tractable social amoeba belonging to the crown group of eukaryotes. It performs some of the tasks characteristic of a leukocyte such as...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

High-Resolution Dissection of Phagosome Maturation Reveals Distinct Membrane Trafficking Phases

Gotthardt, Daniel, Warnatz, Hans Jörg, Henschel, Oliver, Brückert, Franz, Schleicher, Michael, Soldati, Thierry

Molecular mechanisms of endocytosis in the genetically and biochemically tractable professional phagocyte Dictyostelium discoideum reveal a striking degree of similarity to higher eukaryotic cells....

Involvement of the AP-1 Adaptor Complex in Early Steps of Phagocytosis and Macropinocytosis

Lefkir, Yaya, Malbouyres, Marilyne, Gotthardt, Daniel, Ozinsky, Adrian, Cornillon, Sophie, Bruckert, Franz, ...

The best described function of the adaptor complex-1 (AP-1) is to participate in the budding of clathrin-coated vesicles from the trans-Golgi network and endosomes. Here, we show that AP-1 is also...

A Dibasic Motif in the Tail of a Class XIV Apicomplexan Myosin Is an Essential Determinant of Plasma Membrane Localization

Hettmann, Christine, Herm, Angelika, Geiter, Ariane, Frank, Bernd, Schwarz, Eva, Soldati, Thierry, ...

Obligate intracellular parasites of the phylum Apicomplexa exhibit gliding motility, a unique form of substrate-dependent locomotion essential for host cell invasion and shown to involve the parasite...

Identification of a Novel Saturable Endoplasmic Reticulum Localization Mechanism Mediated by the C-Terminus of a Dictyostelium Protein Disulfide Isomerase

Monnat, Jean, Neuhaus, Eva M., Pop, Marius S., Ferrari, David M., Kramer, Barbara, Soldati, Thierry

Localization of soluble endoplasmic reticulum (ER) resident proteins is likely achieved by the complementary action of retrieval and retention mechanisms. Whereas the machinery involving the H/KDEL...

Morphology and Dynamics of the Endocytic Pathway in Dictyostelium discoideumV⃞

Neuhaus, Eva M., Almers, Wolfhard, Soldati, Thierry

Dictyostelium discoideum is a genetically and biochemically tractable social amoeba belonging to the crown group of eukaryotes. It performs some of the tasks characteristic of a leukocyte such as...

Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor

Herm-Götz, Angelika, Weiss, Stefan, Stratmann, Rolf, Fujita-Becker, Setsuko, Ruff, Christine, Meyhöfer, Edgar, ...

Successful host cell invasion is a prerequisite for survival of the obligate intracellular apicomplexan parasites and establishment of infection. Toxoplasma gondii penetrates host cells by an active...

High-Resolution Dissection of Phagosome Maturation Reveals Distinct Membrane Trafficking Phases

Gotthardt, Daniel, Warnatz, Hans Jörg, Henschel, Oliver, Brückert, Franz, Schleicher, Michael, Soldati, Thierry

Molecular mechanisms of endocytosis in the genetically and biochemically tractable professional phagocyte Dictyostelium discoideum reveal a striking degree of similarity to higher eukaryotic cells....

Involvement of the AP-1 Adaptor Complex in Early Steps of Phagocytosis and Macropinocytosis

Lefkir, Yaya, Malbouyres, Marilyne, Gotthardt, Daniel, Ozinsky, Adrian, Cornillon, Sophie, Bruckert, Franz, ...

The best described function of the adaptor complex-1 (AP-1) is to participate in the budding of clathrin-coated vesicles from the trans-Golgi network and endosomes. Here, we show that AP-1 is also...

Dual Targeting of Antioxidant and Metabolic Enzymes to the Mitochondrion and the Apicoplast of Toxoplasma gondii

Pino, Paco, Foth, Bernardo Javier, Kwok, Lai-Yu, Sheiner, Lilach, Schepers, Rebecca, Soldati, Thierry, ...

Toxoplasma gondii is an aerobic protozoan parasite that possesses mitochondrial antioxidant enzymes to safely dispose of oxygen radicals generated by cellular respiration and metabolism. As with most...

Myosin-I nomenclature

Gillespie, Peter G., Albanesi, Joseph P., Bähler, Martin, Bement, William M., Berg, Jonathan S., Burgess, David R., ...

We suggest that the vertebrate myosin-I field adopt a common nomenclature system based on the names adopted by the Human Genome Organization (HUGO). At present, the myosin-I nomenclature is very...

A Myosin I Is Involved in Membrane Recycling from Early Endosomes

Neuhaus, Eva M., Soldati, Thierry

Geometry-based mechanisms have been proposed to account for the sorting of membranes and fluid phase in the endocytic pathway, yet little is known about the involvement of the actin–myosin...

Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite division

Delbac, Frédéric, Sänger, Astrid, Neuhaus, Eva M., Stratmann, Rolf, Ajioka, James W., Toursel, Catherine, ...

In apicomplexan parasites, actin-disrupting drugs and the inhibitor of myosin heavy chain ATPase, 2,3-butanedione monoxime, have been shown to interfere with host cell invasion by inhibiting parasite...