Thilo Kähne

Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pyloriinduced c-Met signal transduction (2008)

Franke, Raimo, Müller, Melanie, Wundrack, Nicole, Gilles, Ernst-Dieter, Klamt, Steffen, Kähne, Thilo, ...

Abstract Background The hepatocyte growth factor (HGF) stimulates mitogenesis, motogenesis, and morphogenesis in a wide range of tissues, including epithelial cells, on binding to the receptor...

Proteolysis of AA Amyloid Fibril Proteins by Matrix Metalloproteinases-1, -2, and -3

Stix, Barbara, Kähne, Thilo, Sletten, Knut, Raynes, John, Roessner, Albert, Röcken, Christoph

We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may participate in amyloidogenesis by either...

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca2+ signaling in B cells

Stork, Björn, Neumann, Konstantin, Goldbeck, Ingo, Alers, Sebastian, Kähne, Thilo, Naumann, Michael, ...

Spatial and temporal modulation of intracellular Ca2+ fluxes controls the cellular response of B lymphocytes to antigen stimulation. Herein, we identify the hematopoietic adaptor protein Dok-3...

Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction

Franke, Raimo, Müller, Melanie, Wundrack, Nicole, Gilles, Ernst-Dieter, Klamt, Steffen, Kähne, Thilo, ...