Thomas Bettecken

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression (2009)

Ising, Marcus, Lucae, Susanne, Binder, Elisabeth B., Bettecken, Thomas, Uhr, Manfred, Ripke, Stephan, ...

CONTEXT: The efficacy of antidepressant drug treatment in depression is unsatisfactory; 1 in 3 patients does not fully recover even after several treatment trials. Genetic factors and clinical...

Systematic mutation analysis of KIAA0767 and KIAA1646 in chromosome 22q-linked periodic catatonia (2005)

Stöber, Gerald, Kohlmann, Bernd, Siekiera, Markus, Rubie, Claudia, Gawlik, Micha, Möller-Ehrlich, Kerstin, ...

Abstract Background Periodic catatonia is a familial subtype of schizophrenia characterized by hyperkinetic and akinetic episodes, followed by a catatonic residual syndrome. The phenotype has been...

Linkage Disequilibrium Patterns and tagSNP Transferability among European Populations

Mueller, Jakob C., Lõhmussaar, Elin, Mägi, Reedik, Remm, Maido, Bettecken, Thomas, Lichtner, Peter, ...

The pattern of linkage disequilibrium (LD) is critical for association studies, in which disease-causing variants are identified by allelic association with adjacent markers. The aim of this study is...

Repertoires of the Nucleosome-Positioning Dinucleotides

Bettecken, Thomas, Trifonov, Edward N.

It is generally accepted that the organization of eukaryotic DNA into chromatin is strongly governed by a code inherent in the genomic DNA sequence. This code, as well as other codes, is superposed...