Thomas Breslin

Immunobiology (2007)

Cd Stimulated Human, Carl-magnus Högerkorp, Sven Bilke, Thomas Breslin, Sigurdur Ingvarsson

this article were defrayed in part by page charge payment. Therefore, and solely to indicate this fact, this article is hereby marked "advertisement" in accordance with 18 U.S.C. section...

Signal transduction pathway profiling of individual tumor samples (2005)

Breslin, Thomas, Krogh, Morten, Peterson, Carsten, Troein, Carl

Abstract Background Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to analyze tumor...

BMC Bioinformatics BioMed Central Research article Signal transduction pathway profiling of individual tumor samples (2005)

Thomas Breslin, Morten Krogh, Carsten Peterson, Carl Troein, Carl Troein

Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to analyze tumor gene...

PROBABILISTIC METHODS IN GENOMIC DATA ANALYSIS (2004)

Breslin, Thomas

In this thesis, three aspects of gene expression data analysis are discussed: Differential gene expression is addressed by a probabilistic method. Gene annotation enrichment analysis is discussed in...

Comparing functional annotation analyses with Catmap (2004)

Breslin, Thomas, Edén, Patrik, Krogh, Morten

Abstract Background Ranked gene lists from microarray experiments are usually analysed by assigning significance to predefined gene categories, e.g ., based on functional annotations. Tools...

Author(s) (2004)

Thomas Breslin, Thomas Breslin

ii Created with the help of PSRaw package (C) 2001-2004 Bo Söderberg DOKUMENTDATABLAD enl SIS 61 41 21

BMC Bioinformatics Methodology article Comparing functional annotation analyses with Catmap (2004)

Thomas Breslin, Patrik Edén, Morten Krogh

Background: Ranked gene lists from microarray experiments are usually analysed by assigning significance to predefined gene categories, e.g., based on functional annotations. Tools performing such...

This Provisional (2004)

Bmc Bioinformatics, Thomas Breslin, Patrik Eden, Morten Krogh, Thomas Breslin, Patrik Edén, ...

PDF corresponds to the article as it appeared upon acceptance. The fully-formatted PDF version will become available shortly after the date of publication, from the URL listed below. Comparing...

Probabilistic estimation of microarray data reliability and underlying gene expression (2003)

Bilke, Sven, Breslin, Thomas, Sigvardsson, Mikael

Abstract Background The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples...

Probabilistic estimation of microarray data reliability and underlying gene expression (2003)

Bilke, Sven, Breslin, Thomas, Sigvardsson, Mikael

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and...

CD44-stimulated human B cells express transcripts specifically involved in immunomodulation and inflammation as analyzed by DNA microarrays (2003)

Högerkorp, Carl-Magnus, Bilke, Sven, Breslin, Thomas, Ingvarsson, Sigurdur, Borrebaeck, Carl A. K.

A number of studies have implicated a role for the cell surface glycoprotein CD44 in several biologic events, such as lymphopoiesis, homing, lymphocyte activation, and apoptosis. We have earlier...

RNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development (2003)

Panagiotis Tsapogas, Thomas Breslin, Sven Bilke, Anna Lagergren, Robert Månsson, David Liberg, ...

The development of a mature B lymphocyte from a bone marrow stem cell is a highly ordered process involving stages with defined features and gene expression patterns. To obtain a deeper understanding...

Open Access (2003)

Sven Bilke, Thomas Breslin, Mikael Sigvardsson

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and...

Early B-Cell Factor, E2A, and Pax-5 Cooperate To Activate the Early B Cell-Specific mb-1 Promoter. (2002)

Sigvardsson, Mikael, Clark, Dawn R, Fitzsimmons, Daniel, Doyle, Michelle, Akerblad, Peter, Breslin, Thomas, ...

Previous studies have suggested that the early-B-cell-specific mb-1(Ig{alpha}) promoter is regulated by EBF and Pax-5. Here, we used in vivo footprinting assays to detect occupation of binding sites...

Early B-Cell Factor, E2A, and Pax-5 Cooperate To Activate the Early B Cell-Specific mb-1 Promoter (2002)

Mikael Sigvardsson, Dawn R. Clark, Daniel Fitzsimmons, Michelle Doyle, Peter A Kerblad, Thomas Breslin, ...

this report, we show that mb-1 transcription correlates with occupancy of multiple promoter binding sites by factors in vivo. Using in vivo footprinting, we identified at least six factor binding...

Early B-Cell Factor, E2A, and Pax-5 Cooperate To Activate the Early B Cell-Specific mb-1 Promoter

Sigvardsson, Mikael, Clark, Dawn R., Fitzsimmons, Daniel, Doyle, Michelle, Åkerblad, Peter, Breslin, Thomas, ...

Previous studies have suggested that the early-B-cell-specific mb-1(Igα) promoter is regulated by EBF and Pax-5. Here, we used in vivo footprinting assays to detect occupation of binding sites in...

Early B-Cell Factor, E2A, and Pax-5 Cooperate To Activate the Early B Cell-Specific mb-1 Promoter

Sigvardsson, Mikael, Clark, Dawn R., Fitzsimmons, Daniel, Doyle, Michelle, Åkerblad, Peter, Breslin, Thomas, ...

Previous studies have suggested that the early-B-cell-specific mb-1(Igα) promoter is regulated by EBF and Pax-5. Here, we used in vivo footprinting assays to detect occupation of binding sites in...