Local Adaptation and Vector-Mediated Population Structure in Plasmodium vivax Malaria (2008)
Joy, Deirdre A., Gonzalez-Ceron, Lilia, Carlton, Jane M., Gueye, Amy, Fay, Michael, McCutchan, Thomas F., ...
Plasmodium vivax in southern Mexico exhibits different infectivities to 2 local mosquito vectors, Anopheles pseudopunctipennis and Anopheles albimanus. Previous work has tied these differences in...
Measuring the Effects of an Ever-Changing Environment on Malaria Control (2006)
McCutchan, Thomas F., Grim, K. C., Li, Jun, Weiss, Walter, Rathore, Darmendar, Sullivan, Margery, ...
The effectiveness of malaria control measures depends not only on the potency of the control measures themselves but also upon the influence of variables associated with the environment....
K. Christiana Grim, Margery Sullivan, Nola Parsons, Thomas F. McCutchan, Michael Cranfield
Five black-footed penguins (Spheniscus demersus) admitted to the Southern African Foundation for the Conservation of Coastal Birds, in Cape Town, South Africa, died from malaria infection. Evidence...
Jessica C. Kissinger, Cleber O. Soares, Rick Paul, Allison M. Wahl, Dharmendar Rathore, ...
Plasmodium (Novyella) juxtanucleare is a widely distributed parasite that primarily infects chickens (Gallus gallus domesticus). All species of Novyella are characterized by very small schizonts,...
Description of a possible clonal expansion of Plasmodium vivax in Manaus - Amazonas - Brazil (1999)
Alecrim,Wilson Duarte, Macêdo,Vanize, Korves,Caroline T., Roberts,Donald R., Li,Jun, ...
Atypical P. vivax cases reported in Manaus municipality led us to detect a genetic isolate of P. vivax. Variable regions of SSUrRNA were examined from the initial time of infection and in the two...
McCutchan, Thomas F., Dame, John B., Gwadz, Robert W., Vernick, Kenneth D.
The genome of Plasmodium cynomolgi is partitioned into at least 7 distinct genetic domains. Each domain is apparently uniform in DNA density and is separable from the others by CsCl density...
Vernick, Kenneth D., Imberski, Richard B., McCutchan, Thomas F.
A novel set of reaction conditions for mung bean nuclease has been described in which Plasmodium genes were specifically excised as intact fragments from purified DNA. We have now determined that...
Vernick, Kenneth D., Walliker, David, McCutchan, Thomas F.
Sequences related to those near chromosome telomeres in the human malaria parasite, Plasmodium falciparum were extremely unstable during a genetic cross between two different clonal genotypes. Many...
Two major sequence classes of ribosomal RNA genes in Plasmodium berghei (1984)
Dame, John B., Sullivan, Margery, McCutchan, Thomas F.
Primary sequence differences have been found between two different ribosomal DNA (rDNA) units of the rodent malaria parasite, Plasmodium berghei within the coding areas of both the small and large...
Thayer, Ronald E., Singer, Maxine F., McCutchan, Thomas F.
Individual monomer and dimer units of the highly repeated α-component DNA of African Green monkeys were isolated and amplified by molecular cloning in pBR322. The purified sequences were...
Rathore, Dharmendar, McCutchan, Thomas F.
Various pathogenic bacteria, viruses, and protozoan bind to glycosaminoglycan-based receptors on host cells and initiate an infection. Sporozoites of Plasmodium predominantly express circumsporozoite...
Rathore, Dharmendar, McCutchan, Thomas F.
Malaria sporozoites are transmitted from the mosquito salivary gland to host hepatocytes within minutes of an infectious bite. The circumsporozoite protein (CS), which covers the surface of...
Rogers, M. John, Cundliffe, Eric, McCutchan, Thomas F.
The antibiotic micrococcin is a potent growth inhibitor of the human malaria parasite Plasmodium falciparum, with a 50% inhibitory concentration of 35 nM. This is comparable to or less than the...
Measuring the Effects of an Ever-Changing Environment on Malaria Control
McCutchan, Thomas F., Grim, K. Christiana, Li, Jun, Weiss, Walter, Rathore, Darmendar, Sullivan, Margery, ...
The effectiveness of malaria control measures depends not only on the potency of the control measures themselves but also upon the influence of variables associated with the environment....
Compensatory evolution in the human malaria parasite Plasmodium ovale.
McCutchan, Thomas F, Rathore, Dharmendar, Li, Jun
The fixation of neutral compensatory mutations in a population depends on the effective population size of the species, which can fluctuate dramatically within a few generations, the mutation rate,...
Rathore, Dharmendar, McCutchan, Thomas F.
Various pathogenic bacteria, viruses, and protozoan bind to glycosaminoglycan-based receptors on host cells and initiate an infection. Sporozoites of Plasmodium predominantly express circumsporozoite...
Rathore, Dharmendar, McCutchan, Thomas F.
Malaria sporozoites are transmitted from the mosquito salivary gland to host hepatocytes within minutes of an infectious bite. The circumsporozoite protein (CS), which covers the surface of...
Rogers, M. John, Cundliffe, Eric, McCutchan, Thomas F.
The antibiotic micrococcin is a potent growth inhibitor of the human malaria parasite Plasmodium falciparum, with a 50% inhibitory concentration of 35 nM. This is comparable to or less than the...
Measuring the Effects of an Ever-Changing Environment on Malaria Control
McCutchan, Thomas F., Grim, K. Christiana, Li, Jun, Weiss, Walter, Rathore, Darmendar, Sullivan, Margery, ...
The effectiveness of malaria control measures depends not only on the potency of the control measures themselves but also upon the influence of variables associated with the environment....
Compensatory evolution in the human malaria parasite Plasmodium ovale.
McCutchan, Thomas F, Rathore, Dharmendar, Li, Jun
The fixation of neutral compensatory mutations in a population depends on the effective population size of the species, which can fluctuate dramatically within a few generations, the mutation rate,...
Oakley, Miranda S. M., Kumar, Sanjai, Anantharaman, Vivek, Zheng, Hong, Mahajan, Babita, Haynes, J. David, ...
Intermittent episodes of febrile illness are the most benign and recognized symptom of infection with malaria parasites, although the effects on parasite survival and virulence remain unclear. In...
Local Adaptation and Vector-Mediated Population Structure in Plasmodium vivax Malaria
Joy, Deirdre A., Gonzalez-Ceron, Lilia, Carlton, Jane M., Gueye, Amy, Fay, Michael, McCutchan, Thomas F., ...
Plasmodium vivax in southern Mexico exhibits different infectivities to 2 local mosquito vectors, Anopheles pseudopunctipennis and Anopheles albimanus. Previous work has tied these differences in...
Use of Malaria Rapid Diagnostic Test to Identify Plasmodium knowlesi Infection
McCutchan, Thomas F., Piper, Robert C., Makler, Michael T.
Reports of human infection with Plasmodium knowlesi, a monkey malaria, suggest that it and other nonhuman malaria species may be an emerging health problem. We report the use of a rapid test to...
Raj, Dipak Kumar, Mu, Jianbing, Jiang, Hongying, Kabat, Juraj, Singh, Subash, Sullivan, Margery, ...
ATP-binding cassette transporters play an important role in drug resistance and nutrient transport. In the human malaria parasite Plasmodium falciparum, a homolog of the human p-glycoprotein...
Oakley, Miranda S., McCutchan, Thomas F., Anantharaman, Vivek, Ward, Jerrold M., Faucette, Laurence, Erexson, Cindy, ...
Cerebral malaria (CM) is a primary cause of malaria-associated deaths among young African children. Yet no diagnostic tools are available that could be used to predict which of the children infected...
Pathogenic Roles of CD14, Galectin-3, and OX40 during Experimental Cerebral Malaria in Mice
Oakley, Miranda S., Majam, Victoria, Mahajan, Babita, Gerald, Noel, Anantharaman, Vivek, Ward, Jerrold M., ...
An in-depth knowledge of the host molecules and biological pathways that contribute towards the pathogenesis of cerebral malaria would help guide the development of novel prognostics and...