identified by gene profiling (2008)
Anna L. Brown, Christopher R. Wilkinson, Scott R. Waterman, Chung H. Kok, Diana G. Salerno, Sonya M. Diakiw, ...
regulators of myelopoiesis and leukemic signaling
Subcellular localization of the Schlafen protein family (2008)
Brent Neumann, Zhao, Liang, Kathleen MURPHY, Gonda, Thomas J.
Lack of reproducible growth inhibition by Schlafen1 and Schlafen2 in vitro (2008)
Zhao, Liang, Neumann, Brent, Murphy, Kathleen, Silke, John, Gonda, Thomas J.
The Schlafen gene family has been implicated in lymphoid and myeloid maturation and differentiation as well as inflammation. However, little is known about the functions of this gene family except...
Drabsch, Yvette, Hugo, Honor, Zhang, Rui, Dowhan, Dennis H., Miao, Yu Rebecca, Gewirtz, Alan M., ...
MYB (the human ortholog of c-myb) is expressed in a high proportion of human breast tumors, and that expression correlates strongly with estrogen receptor (ER) positivity. This may reflect the fact...
Drabsch, Yvette, Hugo, Honor, Zhang, Rui, Dowhan, Dennis H., Miao, Yu Rebecca, Gewirtz, Alan M., ...
MYB (the human ortholog of c-myb) is expressed in a high proportion of human breast tumors, and that expression correlates strongly with estrogen receptor (ER) positivity. This may reflect the fact...
Tanikawa, Jun, Nomura, Teruaki, Macmillan, Elizabeth M., Shinagawa, Toshie, Jin, Wanzhu, Kokura, Kenji, ...
p53 is known to repress transcription of a number of genes, but the mechanism of p53 recruitment to these target genes is unknown. The c-myb proto-oncogene product (c-Myb) positively regulates...
Tanikawa, Jun, Nomura, Teruaki, Macmillan, Elizabeth M., Shinagawa, Toshie, Jin, Wanzhu, Kokura, Kenji, ...
Comment: This paper illustrates another major theme – transformation by MYB - and describes an interaction between MYB and the tumour suppressor, p53 which is clearly one of the most important in...
Tanikawa, Jun, Nomura, Teruaki, Macmillan, Elizabeth M., Shinagawa, Toshie, Jin, Wanzhu, Kokura, Kenji, ...
p53 is known to repress transcription of a number of genes, but the mechanism of p53 recruitment to these target genes is unknown. The c-myb proto-oncogene product (c-Myb) positively regulates...
Regulation of the gene encoding glutathione S-transferase M1 (GSTM1) by the Myb oncoprotein (2003)
Bartley, Paul A., Keough, Rebecca A., Lutwyche, Jodie .K, Gonda, Thomas .J
The identification of Myb 'target' genes will not only aid in the understanding of how overexpression of Myb, or expression of activated forms of Myb, leads to cellular transformation but will also...
Phan, Vernon T., Shultz, David B., Truong, Bao-Tran H., Blake, Timothy J., Brown, Anna L., Gonda, Thomas J., ...
We utilized a mouse model of acute promyelocytic leukemia (APL) to investigate how aberrant activation of cytokine signaling pathways interacts with chimeric transcription factors to generate acute...
Phan, Vernon T., Shultz, David B., Truong, Bao-Tran H., Blake, Timothy J., Brown, Anna L., Gonda, Thomas J., ...
We utilized a mouse model of acute promyelocytic leukemia (APL) to investigate how aberrant activation of cytokine signaling pathways interacts with chimeric transcription factors to generate acute...
Regulation of the gene encoding glutathione S-transferase M1 (GSTM1) by the Myb oncoprotein (2003)
Bartley, Paul A., Keough, Rebecca A., Lutwyche, Jodie .K, Gonda, Thomas .J
The identification of Myb 'target' genes will not only aid in the understanding of how overexpression of Myb, or expression of activated forms of Myb, leads to cellular transformation but will also...
Sobieszczuk, Peter W., Gonda, Thomas J., Dunn, Ashley R.
To study the control mechanism(s) that govern the transcription of c-myb, genomic clones corresponding to the 5′ region of the murine c-myb gene have been isolated and characterized structurally...
Trans-activation by the c-myb proto-oncogene (1989)
Nishina, Yukio, Nakagoshi, Hideki, Imamoto, Fumio, Gonda, Thomas J., Ishii, Shunsuke
We present evidence that the mouse c-myb proto-oncogene encodes a transcriptional trans-activator. Trans-activation was assayed by cotransfection into CV1 monkey kidney cells of a c-myb cDNA...