Taylor, Walter RJ, Widjaja, Hendra, Basri, Hasan, Ohrt, Colin, Tjitra, Emiliana, ...
Abstract Background There are limited data on the evolution of the leukocyte and platelet counts in malaria patients. Methods In a clinical trial of chloroquine vs. chloroquine plus doxycycline vs....
Malaria Vaccines for Travelers (2006)
An effective malaria vaccine would eliminate most of the obstacles to malaria prevention, excepting only the pre-travel visit(s) to receive the vaccine from a health care professional. As with...
Topolska, Agnieszka E., Richie, Thomas L., Nhan, Doan H., Coppel, Ross L.
Rhoptry proteins participate in the invasion of red blood cells by merozoites during the malaria parasite's asexual-stage cycle. Interference with the rhoptry protein function has been shown to...
Update on the Clinical Development of Candidate Malaria Vaccines (2006)
Ballou, W. R., Arevalo-Herrera, Myriam, Carucci, Daniel, Richie, Thomas L., Corradin, Giampietro, Diggs, Carter, ...
The recent availability of significantly increased levels of funding for unmet medical needs in the developing world, made available by newly created public-private partnerships, has proven to be a...
Wang, Ruobing, Epstein, Judith, Charoenvit, Yupin, Baraceros, Fe Maria, Rahardjo, Nancy, Gay, Tanya, ...
Vaccine-induced protection against diseases like malaria, AIDS, and cancer may require induction of Ag-specific CD8 and CD4 T cell and Ab responses in the same individual. In humans, a recombinant...
Epstein, Judith E., Charoenvit, Yupin, Kester, Kent E., Wang, Ruobing, Newcomer, Rhonda, Fitzpatrick, Steve, ...
Optimal protection against malaria may require induction of high levels of protective antibody and CD8+ and CD4+ T cell responses. In humans, malaria DNA vaccines elicit CD8+ cytotoxic T cells (CTL)...
Sedegah, Martha, Rogers, William O., Belmonte, Arnel, Belmonte, Maria, Banania, Glenna, Patterson, Noelle, ...
We evaluated the capacity of the cationic lipid based formulation, Vaxfectin™, to enhance the immunogenicity and protective efficacy of DNA-based vaccine regimens in the Plasmodium yoelii murine...
Wang, Ruobing, Epstein, Judith, Charoenvit, Yupin, Baraceros, Fe Maria, Rahardjo, Nancy, Gay, Tanya, ...
Vaccine-induced protection against diseases like malaria, AIDS, and cancer may require induction of Ag-specific CD8+ and CD4+ T cell and Ab responses in the same individual. In humans, a recombinant...
Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine
Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., ...
We assessed immunogenicity of a malaria DNA vaccine administered by needle i.m. or needleless jet injection [i.m. or i.m./intradermally (i.d.)] in 14 volunteers. Antigen-specific IFN-γ responses...
Weisman, Simon, Wang, Lina, Billman-Jacobe, Helen, Nhan, Doan Hanh, Richie, Thomas L., Coppel, Ross L.
Individuals living in areas where Plasmodium falciparum is endemic experience numerous episodes of infection. These episodes may or may not be symptomatic, with the outcome depending on a combination...
Wang, Lina, Richie, Thomas L., Stowers, Anthony, Nhan, Doan Hanh, Coppel, Ross L.
Merozoite surface protein 4 (MSP4) of Plasmodium falciparum is a glycosylphosphatidylinositol-anchored integral membrane protein that is being developed as a component of a subunit vaccine against...
Tolerability of Azithromycin as Malaria Prophylaxis in Adults in Northeast Papua, Indonesia
Taylor, Walter R., Richie, Thomas L., Fryauff, David J., Ohrt, Colin, Picarima, Helena, Tang, Douglas, ...
Drug tolerability affects compliance. We evaluated the tolerability levels of azithromycin (750-mg loading dose plus 250 mg/day; n = 148 subjects), doxycycline (100 mg/day; n = 75), and placebo (n =...
Topolska, Agnieszka E., Richie, Thomas L., Nhan, Doan Hanh, Coppel, Ross L.
Rhoptry proteins participate in the invasion of red blood cells by merozoites during the malaria parasite's asexual-stage cycle. Interference with the rhoptry protein function has been shown to...
Wang, Ruobing, Richie, Thomas L., Baraceros, Maria Fe, Rahardjo, Nancy, Gay, Tanya, Banania, Jo-Glenna, ...
A mixture of DNA plasmids expressing five Plasmodium falciparum pre-erythrocyte-stage antigens was administered with or without a DNA plasmid encoding human granulocyte-macrophage colony-stimulating...
Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine
Wang, Ruobing, Epstein, Judith, Baraceros, Fe Maria, Gorak, Edward J., Charoenvit, Yupin, Carucci, Daniel J., ...
We assessed immunogenicity of a malaria DNA vaccine administered by needle i.m. or needleless jet injection [i.m. or i.m./intradermally (i.d.)] in 14 volunteers. Antigen-specific IFN-γ responses...
Weisman, Simon, Wang, Lina, Billman-Jacobe, Helen, Nhan, Doan Hanh, Richie, Thomas L., Coppel, Ross L.
Individuals living in areas where Plasmodium falciparum is endemic experience numerous episodes of infection. These episodes may or may not be symptomatic, with the outcome depending on a combination...
Wang, Lina, Richie, Thomas L., Stowers, Anthony, Nhan, Doan Hanh, Coppel, Ross L.
Merozoite surface protein 4 (MSP4) of Plasmodium falciparum is a glycosylphosphatidylinositol-anchored integral membrane protein that is being developed as a component of a subunit vaccine against...
Tolerability of Azithromycin as Malaria Prophylaxis in Adults in Northeast Papua, Indonesia
Taylor, Walter R., Richie, Thomas L., Fryauff, David J., Ohrt, Colin, Picarima, Helena, Tang, Douglas, ...
Drug tolerability affects compliance. We evaluated the tolerability levels of azithromycin (750-mg loading dose plus 250 mg/day; n = 148 subjects), doxycycline (100 mg/day; n = 75), and placebo (n =...
Topolska, Agnieszka E., Richie, Thomas L., Nhan, Doan Hanh, Coppel, Ross L.
Rhoptry proteins participate in the invasion of red blood cells by merozoites during the malaria parasite's asexual-stage cycle. Interference with the rhoptry protein function has been shown to...
Wang, Ruobing, Richie, Thomas L., Baraceros, Maria Fe, Rahardjo, Nancy, Gay, Tanya, Banania, Jo-Glenna, ...
A mixture of DNA plasmids expressing five Plasmodium falciparum pre-erythrocyte-stage antigens was administered with or without a DNA plasmid encoding human granulocyte-macrophage colony-stimulating...
Weiss, Walter R., Kumar, Anita, Jiang, George, Williams, Jackie, Bostick, Anthony, Conteh, Solomon, ...
Jiang, George, Shi, Meng, Conteh, Solomon, Richie, Nancy, Banania, Glenna, Geneshan, Harini, ...
Using newer vaccine platforms which have been effective against malaria in rodent models, we tested five immunization regimens against Plasmodium knowlesi in rhesus monkeys. All vaccines included the...