Menolascina, Filippo, Bellomo, Domenico, Maiwald, Thomas, Bevilacqua, Vitoantonio, Ciminelli, Caterina, Paradiso, Angelo, ...
Abstract Background Mechanistic models are becoming more and more popular in Systems Biology; identification and control of models underlying biochemical pathways of interest in oncology is a primary...
Dynamical modeling and multi-experiment fitting with
Pages 1–7 Dynamical Modeling and Multi-Experiment Fitting with (2009)
Received on; revised on; accepted on
Host Cell Responses Induced by Hepatitis C Virus Binding (2009)
Xinhua Fang, Mirjam B. Zeisel, Jochen Wilpert, Bettina Gissler, Robert Thimme, Clemens Kreutz, ...
Initiation of hepatitis C virus (HCV) infection is mediated by docking of the viral envelope to the hepatocyte cell surface membrane followed by entry of the virus into the host cell. Aiming to...
Dynamical Modeling and Multi-Experiment Fitting with PottersWheel – Supplement (2008)
This supplement provides detailed information about the functionalities of the Potters-Wheel toolbox as described in the main text. For further information please use the
Dynamical modeling and multi-experiment fitting with PottersWheel (2008)
Motivation: Modelers in Systems Biology need a flexible framework that allows them to easily create new dynamic models, investigate their properties and fit several experimental datasets...
Dynamic pathway modeling: feasibility analysis and optimal experimental design (2007)
Thomas Maiwald, A Clemens Kreutz
ABSTRACT: A major challenge in systems biology is to evaluate the feasibility of a biological research project prior to its realization. Since experiments are animals-, cost- and time-consuming,...
Björn Schelter, Matthias Winterhalder, Thomas Maiwald, Armin Br, Ariane Schad, Jens Timmer, ...
are accompanied by high numbers of false predictions to achieve high sensitivity. Little is known about the extent to which changes in EEG dynamics contribute to false predictions. This study...
Host cell responses induced by hepatitis C virus binding. (2006)
Fang, Xinhua, Zeisel, Mirjam B, Wilpert, Jochen, Gissler, Bettina, Thimme, Robert, Kreutz, Clemens, ...
Initiation of hepatitis C virus (HCV) infection is mediated by docking of the viral envelope to the hepatocyte cell surface membrane followed by entry of the virus into the host cell. Aiming to...
Host cell responses induced by hepatitis C virus binding. (2006)
Fang, Xinhua, Zeisel, Mirjam B, Wilpert, Jochen, Gissler, Bettina, Thimme, Robert, Kreutz, Clemens, ...
Initiation of hepatitis C virus (HCV) infection is mediated by docking of the viral envelope to the hepatocyte cell surface membrane followed by entry of the virus into the host cell. Aiming to...
Host cell responses induced by hepatitis C virus binding. (2006)
Fang, Xinhua, Zeisel, Mirjam B, Wilpert, Jochen, Gissler, Bettina, Thimme, Robert, Kreutz, Clemens, ...
Initiation of hepatitis C virus (HCV) infection is mediated by docking of the viral envelope to the hepatocyte cell surface membrane followed by entry of the virus into the host cell. Aiming to...
Clemens Kreutz, Johannes Donauer, Daniel Faller, Thomas Maiwald, Edith März, Titus Sparna, ...
Polycythaemia vera (PV) is one of four diseases termed the myeloproliferative disorders (MPDs) (Dameshek, 1951). Besides PV this group includes essential thrombocythaemia (ET), idiopathic...
Marcel Schilling, Thomas Maiwald, Sebastian Bohl, Markus Kollmann, Clemens Kreutz, Jens Timmer, ...
processing and error reduction strategies
Dynamical modeling and multi-experiment fitting with PottersWheel
Motivation: Modelers in Systems Biology need a flexible framework that allows them to easily create new dynamic models, investigate their properties and fit several experimental datasets...
Systems-level interactions between insulin–EGF networks amplify mitogenic signaling
Borisov, Nikolay, Aksamitiene, Edita, Kiyatkin, Anatoly, Legewie, Stefan, Berkhout, Jan, Maiwald, Thomas, ...
Crosstalk mechanisms have not been studied as thoroughly as individual signaling pathways. We exploit experimental and computational approaches to reveal how a concordant interplay between the...