Hoffmann, Karl, McCarty, Thomas, Segal, David, Chiaramonte, Monica, Hesse, Matthias, Davis, Eric
Development of polarized immune responses controls resistance and susceptibility to many microorganisms. However, studies of several infectious, allergic, and autoimmune diseases have shown that...
Hoffmann, Karl, McCarty, Thomas, Segal, David, Chiaramonte, Monica, Hesse, Matthias, Davis, Eric
Development of polarized immune responses controls resistance and susceptibility to many microorganisms. However, studies of several infectious, allergic, and autoimmune diseases have shown that...
Morse, Herbert C., McCarty, Thomas, Giese, Nathalia A., Taddesse-Heath, Lekidelu, Grusby, Michael J.
The unique Gag polyprotein of the replication-defective virus responsible for murine AIDS (MAIDS) induces B-cell activation, proliferation, and differentiation, including immunoglobulin class...
Reductions in IκBε and Changes in NF-κB Activity during B Lymphocyte Differentiation1
Doerre, Stefan, Mesires, Kristin Perkins, Daley, Kylle M., McCarty, Thomas, Knoetig, Sonja, Corley, Ronald B.
The levels and stability of IκBε have been examined in unstimulated and stimulated splenic B cells and compared with that of IκBα and IκBβ. Primary murine splenic B cells but not T cells were...
Morse, Herbert C., McCarty, Thomas, Giese, Nathalia A., Taddesse-Heath, Lekidelu, Grusby, Michael J.
The unique Gag polyprotein of the replication-defective virus responsible for murine AIDS (MAIDS) induces B-cell activation, proliferation, and differentiation, including immunoglobulin class...
Immunoglobulin Class Switch Recombination Is Impaired in Atm-deficient Mice
Lumsden, Joanne M., McCarty, Thomas, Petiniot, Lisa K., Shen, Rhuna, Barlow, Carrolee, Wynn, Thomas A., ...
Immunoglobulin class switch recombination (Ig CSR) involves DNA double strand breaks (DSBs) at recombining switch regions and repair of these breaks by nonhomologous end-joining. Because the protein...
Zhang, Jian Qiao, Okumura, Cheryl, McCarty, Thomas, Shin, Min Sun, Mukhopadhyay, Partha, Hori, Mitsuo, ...
Germline mutations in Fas and Fasl induce nonmalignant T cell hyperplasia and systemic autoimmunity and also greatly increase the risk of B cell neoplasms. B lymphomas occurring in Fasl mutant (gld)...