Thomas P. J. Garrett

Mutant barley (1{->}3,1{->}4)-{beta}-glucan endohydrolases with enhanced thermostability (2001)

Stewart, Richard J., Varghese, Jose N., Garrett, Thomas P.J., Høj, Peter B., Fincher, Geoffrey B.

The similar three-dimensional structures of barley (1→3)-β-glucan endohydrolases and (1→3,1→4)-β-glucan endohydrolases indicate that the enzymes are closely related in evolutionary terms....

Polysaccharide hydrolases in germinated barley and their role in the depolymerization of plant and fungal cell walls (1997)

Hrmova, Maria, Banik, M., Harvey, Andrew J., Garrett, Thomas P. J., Varghese, Jose N., Hoj, Peter B., ...

Polysaccharide hydrolases in germinated barley and their role in the depolymerization of plant and fungal cell walls (1997)

Hrmova, Maria, Banik, M., Harvey, Andrew J., Garrett, Thomas P. J., Varghese, Jose N., Hoj, Peter B., ...

The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity

Lou, Meizhen, Garrett, Thomas P. J., McKern, Neil M., Hoyne, Peter A., Epa, V. Chandana, Bentley, John D., ...

The insulin receptor (IR) and the type-1 insulin-like growth factor receptor (IGF1R) are homologous multidomain proteins that bind insulin and IGF with differing specificity. Here we report the...

An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor

Huyton, Trevor, Zhang, Jian-Guo, Luo, Cindy S., Lou, Mei-Zhen, Hilton, Douglas J., Nicola, Nicos A., ...

Leukemia inhibitory factor (LIF) receptor is a cell surface receptor that mediates the actions of LIF and other IL-6 type cytokines through the formation of high-affinity signaling complexes with...

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR

Garrett, Thomas P. J., Burgess, Antony W., Gan, Hui K., Luwor, Rod B., Cartwright, Glenn, Walker, Francesca, ...

Epidermal Growth Factor Receptor (EGFR) is involved in stimulating the growth of many human tumors, but the success of therapeutic agents has been limited in part by interference from the EGFR on...