Song, Yiqing, Hsu, Yi-Hsiang, Niu, Tianhua, Manson, JoAnn E, Buring, Julie E, Liu, Simin
Abstract Background Ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7) play a central role in magnesium homeostasis, which is critical for maintaining glucose and...
Wang, Lin, Liu, Simin, Niu, Tianhua, Xu, Xin
Abstract Background Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. Selection and...
Running Title: SNPicker: A Graphical Tool for Primer Picking (2004)
Tianhua Niu, Zhenjun Hu, Address For Correspondence
Summary: Simple, low-cost, and accurate genotyping methods for single nucleotide polymorphisms (SNPs) are in high demand in the post-genome-sequencing era. We present a graphical tool called...
Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...
Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...
Summary: Simple, low-cost, and accurate genotyping methods for single nucleotide polymorphisms (SNPs) are in high demand in the post-genome-sequencing era. We present a graphical tool called...
Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...
Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...
Summary: Simple, low-cost and accurate genotyping methods for single nucleotide polymorphisms (SNPs) are in high demand in the post-genome-sequencing era. We present a graphical tool called SNPicker,...
Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...
Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...
Summary: Simple, low-cost, and accurate genotyping methods for single nucleotide polymorphisms (SNPs) are in high demand in the post-genome-sequencing era. We present a graphical tool called...
SeqVISTA: a graphical tool for sequence feature visualization and comparison (2003)
Hu, Zhenjun, Frith, Martin, Niu, Tianhua, Weng, Zhiping
Abstract Background Many readers will sympathize with the following story. You are viewing a gene sequence in Entrez, and you want to find whether it contains a particular sequence motif. You reach...
Zhenjun Hu, Martin Frith, Tianhua Niu, Zhiping Weng, Zhiping Weng
comparison
Haplotype Information and Linkage Disequilibrium Mapping for Single Nucleotide Polymorphisms (2003)
Lu, Xin, Niu, Tianhua, Liu, Jun S.
Single nucleotide polymorphisms in the human genome have become an increasingly popular topic in that their analyses promise to be a key step toward personalized medicine. We investigate two related...
Niu, Tianhua., Seielstad, Mark., Zeng, Xuan., Li, Guang., Apffel, Alex., Hahnenberger, Karen., ...
Human Biology - Volume 73, Number 3, June 2001
Nicotine dependence and its familial aggregation in Chinese (2000)
Niu, Tianhua, Chen, Changzhong, Ni, Jiatong, Wang, Binyan, Fang, Zhian, Shao, Hong, ...
Background Nicotine dependence is a significant public health problem. This study attempted to characterize the prevalence and familial aggregation of nicotine dependence in China. Methods In 1998,...
Wang, Xiaobin, Chen, Dafang, Niu, Tianhua, Wang, Zhaoxi, Wang, Lihua, Ryan, Louise, ...
This study investigated whether the association between low level benzene exposure and shortened gestation is modified by two susceptibility genes, CYP1A1 and GSTT1. This report includes 542 (302...
Genetic epidemiology of hypertension in Chinese / (1998)
Thesis (Doctor of Science)--Harvard School of Public Health, 1998.
Wulf, Gerburg M., Ryo, Akihide, Wulf, Gerald G., Lee, Sam W., Niu, Tianhua, Petkova, Victoria, ...
Phosphorylation on serines or threonines preceding proline (Ser/Thr-Pro) is a major signaling mechanism. The conformation of a subset of phosphorylated Ser/Thr-Pro motifs is regulated by the prolyl...
Haplotype Information and Linkage Disequilibrium Mapping for Single Nucleotide Polymorphisms
Lu, Xin, Niu, Tianhua, Liu, Jun S.
Single nucleotide polymorphisms in the human genome have become an increasingly popular topic in that their analyses promise to be a key step toward personalized medicine. We investigate two related...
Niu, Tianhua, Ding, Adam A., Kreutz, Reinhold, Lindpaintner, Klaus
The mapping of quantitative trait loci (QTL) is an important research question in animal and human studies. Missing data are common in such study settings, and ignoring such missing data may result...
Wulf, Gerburg M., Ryo, Akihide, Wulf, Gerald G., Lee, Sam W., Niu, Tianhua, Petkova, Victoria, ...
Phosphorylation on serines or threonines preceding proline (Ser/Thr-Pro) is a major signaling mechanism. The conformation of a subset of phosphorylated Ser/Thr-Pro motifs is regulated by the prolyl...
Haplotype Information and Linkage Disequilibrium Mapping for Single Nucleotide Polymorphisms
Lu, Xin, Niu, Tianhua, Liu, Jun S.
Single nucleotide polymorphisms in the human genome have become an increasingly popular topic in that their analyses promise to be a key step toward personalized medicine. We investigate two related...
Bayesian Haplotype Inference for Multiple Linked Single-Nucleotide Polymorphisms
Niu, Tianhua, Qin, Zhaohui S., Xu, Xiping, Liu, Jun S.
Haplotypes have gained increasing attention in the mapping of complex-disease genes, because of the abundance of single-nucleotide polymorphisms (SNPs) and the limited power of conventional...
Song, Yiqing, Niu, Tianhua, Manson, JoAnn E., Kwiatkowski, David J., Liu, Simin
The calpain-10 gene (CAPN10) on chromosome 2q37.3 was the first candidate gene for type 2 diabetes (T2D) identified through a genomewide screen and positional cloning. One polymorphism (UCSNP-43:...
Feng, Yan, Niu, Tianhua, Xing, Houxun, Xu, Xin, Chen, Changzhong, Peng, Shaojie, ...
Nicotine is the major addictive substance in cigarettes, and genes involved in sensing nicotine are logical candidates for vulnerability to nicotine addiction. We studied six single-nucleotide...
Incorporating Genotyping Uncertainty in Haplotype Inference for Single-Nucleotide Polymorphisms
Kang, Hosung, Qin, Zhaohui S., Niu, Tianhua, Liu, Jun S.
The accuracy of the vast amount of genotypic information generated by high-throughput genotyping technologies is crucial in haplotype analyses and linkage-disequilibrium mapping for complex diseases....
Niu, Tianhua, Ding, Adam A., Kreutz, Reinhold, Lindpaintner, Klaus
The mapping of quantitative trait loci (QTL) is an important research question in animal and human studies. Missing data are common in such study settings, and ignoring such missing data may result...
A Coalescence-Guided Hierarchical Bayesian Method for Haplotype Inference
Zhang, Yu, Niu, Tianhua, Liu, Jun S.
Haplotype inference from phase-ambiguous multilocus genotype data is an important task for both disease-gene mapping and studies of human evolution. We report a novel haplotype-inference method based...