Tiffany A. Greenwood

The Consortium on the Genetics of Endophenotypes in Schizophrenia: Model Recruitment, Assessment, and Endophenotyping Methods for a Multisite Collaboration (2007)

Calkins, Monica E., Dobie, Dorcas J., Cadenhead, Kristin S., Olincy, Ann, Freedman, Robert, Green, Michael F., ...

Background: The Consortium on the Genetics of Schizophrenia (COGS) is an ongoing, National Institute of Mental Health–funded, 7-site collaboration investigating the occurrence and genetic...

Statistical Genetics Concepts and Approaches in Schizophrenia and Related Neuropsychiatric Research (2007)

Schork, Nicholas J., Greenwood, Tiffany A., Braff, David L.

Statistical genetics is a research field that focuses on mathematical models and statistical inference methodologies that relate genetic variations (ie, naturally occurring human DNA sequence...

The Consortium on the Genetics of Endophenotypes in Schizophrenia: Model Recruitment, Assessment, and Endophenotyping Methods for a Multisite Collaboration (2006)

Calkins, Monica E., Dobie, Dorcas J., Cadenhead, Kristin S., Olincy, Ann, Freedman, Robert, Green, Michael F., ...

Background: The Consortium on the Genetics of Schizophrenia (COGS) is an ongoing, National Institute of Mental Health-funded, 7-site collaboration investigating the occurrence and genetic...

Statistical Genetics Concepts and Approaches in Schizophrenia and Related Neuropsychiatric Research (2006)

Schork, Nicholas J., Greenwood, Tiffany A., Braff, David L.

Statistical genetics is a research field that focuses on mathematical models and statistical inference methodologies that relate genetic variations (ie, naturally occurring human DNA sequence...

Human Haplotype Block Sizes Are Negatively Correlated With Recombination Rates (2004)

Greenwood, Tiffany A., Rana, Brinda K., Schork, Nicholas J.

The International Haplotype Map (“HapMap”) Project is motivated, in part, by the belief that the organization of the human genome, the mechanics of recombination, and the population-level...

Human Haplotype Block Sizes Are Negatively Correlated With Recombination Rates

Greenwood, Tiffany A., Rana, Brinda K., Schork, Nicholas J.

The International Haplotype Map (“HapMap”) Project is motivated, in part, by the belief that the organization of the human genome, the mechanics of recombination, and the population-level...

Human Haplotype Block Sizes Are Negatively Correlated With Recombination Rates

Greenwood, Tiffany A., Rana, Brinda K., Schork, Nicholas J.

The International Haplotype Map (“HapMap”) Project is motivated, in part, by the belief that the organization of the human genome, the mechanics of recombination, and the population-level...

Inherent Bias toward the Null Hypothesis in Conventional Multipoint Nonparametric Linkage Analysis

Schork, Nicholas J., Greenwood, Tiffany A.

Traditional nonparametric “multipoint” statistical procedures have been developed for assigning allele-sharing values at a locus of interest to pairs of relatives for linkage studies. These...

Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure Program

Greenwood, Tiffany A., Libiger, Ondrej, Kardia, Sharon, Hanis, Craig, Morrison, Alanna C., Gu, C. Charles, ...

Linkage analyses of complex, multifactorial traits and diseases, such as essential hypertension, have been difficult to interpret and reconcile. Many published studies provide evidence suggesting...

Advances in endophenotyping schizophrenia

BRAFF, DAVID L., GREENWOOD, TIFFANY A., SWERDLOW, NEAL R., LIGHT, GREGORY A., SCHORK, NICHOLAS J.

The search for the genetic architecture of schizophrenia has employed multiple, often converging strategies. One such strategy entails the use of tracing the heritability and neurobiology of...

Statistical Genetics Concepts and Approaches in Schizophrenia and Related Neuropsychiatric Research

Schork, Nicholas J., Greenwood, Tiffany A., Braff, David L.

Statistical genetics is a research field that focuses on mathematical models and statistical inference methodologies that relate genetic variations (ie, naturally occurring human DNA sequence...

The Consortium on the Genetics of Endophenotypes in Schizophrenia: Model Recruitment, Assessment, and Endophenotyping Methods for a Multisite Collaboration

Calkins, Monica E., Dobie, Dorcas J., Cadenhead, Kristin S., Olincy, Ann, Freedman, Robert, Green, Michael F., ...

Background: The Consortium on the Genetics of Schizophrenia (COGS) is an ongoing, National Institute of Mental Health–funded, 7-site collaboration investigating the occurrence and genetic...

Transcription Factor SP4 Is a Susceptibility Gene for Bipolar Disorder

Zhou, Xianjin, Tang, Wei, Greenwood, Tiffany A., Guo, Shengzhen, He, Lin, Geyer, Mark A., ...

The Sp4 transcription factor plays a critical role for both development and function of mouse hippocampus. Reduced expression of the mouse Sp4 gene results in a variety of behavioral abnormalities...