Tiina Paunio

Common variants conferring risk of schizophrenia (2009)

Stefansson, Hreinn, Ophoff, Roel A, Steinberg, Stacy, Andreassen, Ole A, Cichon, Sven, Rujescu, Dan, ...

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Longitudinal Study on Poor Sleep and Life Dissatisfaction in a Nationwide Cohort of Twins (2009)

Paunio, Tiina, Korhonen, Tellervo, Hublin, Christer, Partinen, Markku, Kivimäki, Mika, Koskenvuo, Markku, ...

Life satisfaction and quality of sleep are important, related components of subjective well-being and general health. However, no earlier investigation is known to have tested the direction of the...

Large recurrent microdeletions associated with schizophrenia (2008)

Stefansson, Hreinn, Rujescu, Dan, Cichon, Sven, Pietiläinen, Olli P H, Ingason, Andres, Steinberg, Stacy, ...

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Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments (2007)

Palo, Outi M., Antila, Mervi, Silander, Kaisa, Hennah, William, Kilpinen, Helena, Soronen, Pia, ...

Bipolar disorder (BPD) and schizophrenia (SCZ) have at least a partially convergent aetiology and thus may share genetic susceptibility loci. Multiple lines of evidence emphasize the role of...

Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1 (2007)

Hennah, William, Tomppo, Liisa, Hiekkalinna, Tero, Palo, Outi M., Kilpinen, Helena, Ekelund, Jesper, ...

We have previously reported a robust association between an allelic haplotype of ‘Disrupted in Schizophrenia 1’ (DISC1) and schizophrenia in a nationwide collection of Finnish schizophrenia...

Families with the Risk Allele of DISC1 Reveal a Link Between Schizophrenia and Another Component of the Same Molecular Pathway, NDE1. (2006)

Hennah, William, Tomppo, Liisa, Hiekkalinna, Tero, Palo, Outi M, Kilpinen, Helena, Ekelund, Jesper, ...

We have previously reported a robust association between an allelic haplotype of DISC1 and schizophrenia in a nationwide collection of Finnish schizophrenia families. This specific DISC1 allele was...

Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q (2004)

Paunio, Tiina, Tuulio-Henriksson, Annamari, Hiekkalinna, Tero, Perola, Markus, Varilo, Teppo, Partonen, Timo, ...

Research to identify predisposing genes for complex diseases relying solely on clinical diagnosis is probably not ideal. Here, we analysed genomewide data for 168 schizophrenia families using...

Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q (2004)

Paunio, Tiina, Tuulio-Henriksson, Annamari, Hiekkalinna, Tero, Perola, Markus, Varilo, Teppo, Partonen, Timo, ...

Research to identify predisposing genes for complex diseases relying solely on clinical diagnosis is probably not ideal. Here, we analyzed genome-wide data for 168 schizophrenia families using...

Search for cognitive trait components of schizophrenia reveals a locus for verbal learning and memory on 4q and for visual working memory on 2q (2004)

Paunio, Tiina, Tuulio-Henriksson, Annamari, Hiekkalinna, Tero, Perola, Markus, Varilo, Teppo, Partonen, Timo, ...

Research to identify predisposing genes for complex diseases relying solely on clinical diagnosis is probably not ideal. Here, we analysed genomewide data for 168 schizophrenia families using...

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia (2003)

Lewis, Cathryn M, Levinson, Douglas F, Wise, Lesley H, DeLisi, Lynn E, Straub, Richard E, Hovatta, Iiris, ...

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Evidence of susceptibility loci on 4q32 and 16p12 for bipolar disorder (2003)

Ekholm, Jenny M., Kieseppä, Tuula, Hiekkalinna, Tero, Partonen, Timo, Paunio, Tiina, Perola, Markus, ...

We performed a genome-wide scan for susceptibility loci in bipolar disorder in a study sample colleted from the isolated Finnish population, consisting of 41 families with at least two affected...

Haplotype Transmission Analysis Provides Evidence of Association for DISC1 to Schizophrenia and Suggests Sex-Dependent Effects (2003)

Hennah, William, Varilo, Teppo, Kestilä, Marjo, Paunio, Tiina, Arajärvi, Ritva, Haukka, Jari, ...

We have previously reported a linkage peak on 1q42 in a Finnish schizophrenia sample. In this study we genotyped 28 single nucleotide polymorphisms (SNPs) from 1q42 covering the three candidate genes...

Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects (2003)

Hennah, William, Varilo, Teppo, Kestilä, Marjo, Paunio, Tiina, Arajärvi, Ritva, Haukka, Jari, ...

We have previously reported a linkage peak on 1q42 in a Finnish schizophrenia sample. In this study we genotyped 28 single nucleotide polymorphisms (SNPs) from 1q42 covering the three candidate genes...

Haplotype Transmission Analysis Provides Evidence of Association for DISC1 to Schizophrenia and Suggests Sex-Dependent Effects (2003)

Hennah, William, Varilo, Teppo, Kestilä, Marjo, Paunio, Tiina, Arajärvi, Ritva, Haukka, Jari, ...

We have previously reported a linkage peak on 1q42 in a Finnish schizophrenia sample. In this study we genotyped 28 single nucleotide polymorphisms (SNPs) from 1q42 covering the three candidate genes...

Chromosome 1 loci in Finnish schizophrenia families (2001)

Ekelund, Jesper, Hovatta, Iiris, Parker, Alex, Paunio, Tiina, Varilo, Teppo, Martin, Rory, ...

We have earlier reported evidence for linkage to two regions on chromosome 1q32–q42 in schizophrenia families collected for two separate studies in Finland. Here we report the results of a fine...

RHD Maternal-Fetal Genotype Incompatibility Increases Schizophrenia Susceptibility

Palmer, Christina G. S., Turunen, Joni A., Sinsheimer, Janet S., Minassian, Sonia, Paunio, Tiina, Lönnqvist, Jouko, ...

Fetal events and obstetric complications are associated with schizophrenia. Here we report the results of a family-based candidate-gene study that assesses the role of maternal-fetal genotype...

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part II: Schizophrenia

Lewis, Cathryn M., Levinson, Douglas F., Wise, Lesley H., DeLisi, Lynn E., Straub, Richard E., Hovatta, Iiris, ...

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to siblings of probands. Replication has been inconsistent for reports of significant genetic linkage. To...

The Genome-wide Patterns of Variation Expose Significant Substructure in a Founder Population

Jakkula, Eveliina, Rehnström, Karola, Varilo, Teppo, Pietiläinen, Olli P.H., Paunio, Tiina, Pedersen, Nancy L., ...

Although high-density SNP genotyping platforms generate a momentum for detailed genome-wide association (GWA) studies, an offshoot is a new insight into population genetics. Here, we present an...