Till T. Bachmann

Fluorescence Lifetime Imaging of Quantum Dot Labeled DNA Microarrays (2009)

Gerard Giraud, Holger Schulze, Till T. Bachmann, Colin J. Campbell, Andrew R. Mount, Peter Ghazal, ...

Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a powerful transduction technique for the detection of DNA hybridization events. Fluorescence lifetime...

Screen-printed bienzymatic sensor based on sol-gel immobilized Nippostrongylus brasiliensis acetylcholinesterase and a cytochrome P450 BM-3 (CYP102-A1) mutant (2006)

Waibel, Michael, Schulze, Holger, Huber, Norbert, Bachmann, Till T.

Here we describe the development of a bienzymatic biosensor that simplifies the sample pretreatment steps for insecticide detection, and enables the highly sensitive detection of phosphorothionates...

GenoMik - Kompetenzzentrum Genomforschung an pathogenen Bakterien, Teilvorhaben: Schnelldiagnose von Antibiotikaresistenzen in der Medizin (2005)

Bachmann,Till T., Schmid, Rolf D.

Entwicklung und Herstellung von DNA-Microarrays zur Schnelldiagnose Antibiotikaresistenter Bakterien in der Medizin. Die Testergebnisse sollen in kürzester Zeit (< 4 h) vorliegen, eine...

GenoMik - Kompetenzzentrum Genomforschung an pathogenen Bakterien - Teilvorhaben: Schnelldiagnose von Antibiotikaresistenzen in der Medizin (2005)

Bachmann,Till T., Schmid, Rolf D.

Entwicklung und Herstellung von DNA-Microarrays zur Schnelldiagnose Antibiotikaresistenter Bakterien in der Medizin. Die Testergebnisse sollen in kürzester Zeit (< 4 h) vorliegen, eine...

Design of acetylcholinesterases for biosensor applications (2003)

Schulze, Holger, Vorlová, Sandra, Villatte, Francois, Bachmann, Till T., Schmid, Rolf D.

In recent years, the use of acetylcholinesterases (AChEs) in biosensor technology has gained enormous attention, in particular with respect to insecticide detection. The principle of biosensors using...

A disposable acetylcholinesterase-based electrode biosensor to detect anatoxin-a(s) in water (2002)

Villatte, Francois, Schulze, Holger, Schmid, Rolf D., Bachmann, Till T.

Anatoxin-a(s) is a hazardous toxin released by cyanobacteria during bacterial blooms. A simple and fast method to detect this hazardous compound using a biosensor based on the electrochemical...

A disposable acetylcholinesterase-based electrode biosensor to detect anatoxin-a(s) in water (2002)

Villatte, Francois, Schulze, Holger, Schmid, Rolf D., Bachmann, Till T.

Anatoxin-a(s) is a hazardous toxin released by cyanobacteria during bacterial blooms. A simple and fast method to detect this hazardous compound using a biosensor based on the electrochemical...

Development, validation, and application of an acetylcholinesterase-biosensor test for the direct detection of insecticide residues in infant food (2002)

Schulze, Holger, Scherbaum, Ellen, Anastassiades, Michelangelo, Vorlová, Sandra, Schmid, Rolf D., Bachmann, Till T.

A highly sensitive and rapid food-screening test based on disposable screen-printed biosensors was developed, which is suitable for monitoring infant food. The exposure of infants and children to...

Rapid detection of neurotoxic insecticides in food using disposable acetylcholinesterase-biosensors and simple solvent extraction (2002)

Schulze, Holger, Schmid, Rolf D., Bachmann, Till T.

The extensive use of pesticides to protect agricultural crops necessitates reliable tools for the detection of residues in food and water, thus ensuring environmental protection and consumer safety....

Mapping of a hapten-binding site: molecular modeling and site-directed mutagenesis study of an anti-atrazine antibody (2002)

Kusharyoto, Wien, Pleiss, Jürgen, Bachmann, Till T., Schmid, Rolf D.

A three-dimensional model of the variable domain of the atrazine-specific Fab fragment K411B was constructed by molecular modeling using known structures of highly homologous immunoglobulins as...

Ein mehrkanaliges Biosensormesssystem zur Überwachung der Nitrifikation in Abwasserreinigungsanlagen (2001)

Bachmann, Till T., Metzger, J. W., Baumeister, F., König, A., Kunzmann, K., Riechert, F., ...

Bei der biologischen Abwasserreinigung treten häufig Störungen der Nitrifikationsstufe (biochemische Oxidation von Ammonium über Nitrit zu Nitrat) auf, die durch Hemmstoffe sowie durch...

Neurotoxin detection in food using disposable AChE-biosensors (2001)

Bachmann, Till T., Schmid, Rolf D., Villatte, Francois, Schulze, Holger

The extensive use of pesticides to protect agricultural crops necessitates reliable tools for the detection of residues in food and water, thus ensuring environmental protection and consumer safety....

Monitoring of Nutrient Bioavailability Using Recombinant Cyanobacterial Reporter Strains (2001)

Mbeunkui, Flaubert, Schreiter, Pat, Gillor, Osnat, Richaud, Catherine, Belkin, Shimshon, Etienne, Anne-Lise, ...

Massive growth of cyanobacteria, known as 'algal blooms', have become a major concern for water monitoring. Besides their negative effect on turbidity, taste and smell, cyanobacteria are associated...

Development of Disposable Sensors for Rapid Multianalyte Detection: Acetylcholinesterase and Microbial Biosensors (1999)

Bachmann, Till T.

Der Gegenstand dieser Arbeit war die Entwicklung von neuen Biosensoren zum simultanen Nachweis und der Klassifizierung von Stoffgemischen in der Umweltanalytik. Diese neuartigen Systeme sollten zur...

Development of Disposable Sensors for Rapid Multianalyte Detection: Acetylcholinesterase and Microbial Biosensors (1999)

Bachmann, Till T.

Der Gegenstand dieser Arbeit war die Entwicklung von neuen Biosensoren zum simultanen Nachweis und der Klassifizierung von Stoffgemischen in der Umweltanalytik. Diese neuartigen Systeme sollten zur...

Use of DNA Microarrays for Rapid Genotyping of TEM Beta-Lactamases That Confer Resistance

Grimm, Verena, Ezaki, Satoshi, Susa, Milorad, Knabbe, Cornelius, Schmid, Rolf. D., Bachmann, Till T.

Standard clinical procedures for pathogen resistance identification are laborious and usually require 2 days of cultivation before the resistance can be determined unequivocally. In contrast,...

Development and Validation of a Diagnostic DNA Microarray To Detect Quinolone-Resistant Escherichia coli among Clinical Isolates

Yu, Xiaolei, Susa, Milorad, Knabbe, Cornelius, Schmid, Rolf D., Bachmann, Till T.

The incidence of resistance against fluoroquinolones among pathogenic bacteria has been increasing in accordance with the worldwide use of this drug. Escherichia coli is one of the most relevant...

Development of a DNA Microarray for Detection and Identification of Fungal Pathogens Involved in Invasive Mycoses

Leinberger, Dirk M., Schumacher, Ulrike, Autenrieth, Ingo B., Bachmann, Till T.

Invasive fungal infections have emerged as a major cause of morbidity and mortality in immunocompromised patients. Conventional identification of pathogenic fungi in clinical microbiology...

Use of DNA Microarrays for Rapid Genotyping of TEM Beta-Lactamases That Confer Resistance

Grimm, Verena, Ezaki, Satoshi, Susa, Milorad, Knabbe, Cornelius, Schmid, Rolf. D., Bachmann, Till T.

Standard clinical procedures for pathogen resistance identification are laborious and usually require 2 days of cultivation before the resistance can be determined unequivocally. In contrast,...

Development and Validation of a Diagnostic DNA Microarray To Detect Quinolone-Resistant Escherichia coli among Clinical Isolates

Yu, Xiaolei, Susa, Milorad, Knabbe, Cornelius, Schmid, Rolf D., Bachmann, Till T.

The incidence of resistance against fluoroquinolones among pathogenic bacteria has been increasing in accordance with the worldwide use of this drug. Escherichia coli is one of the most relevant...

Development of a DNA Microarray for Detection and Identification of Fungal Pathogens Involved in Invasive Mycoses

Leinberger, Dirk M., Schumacher, Ulrike, Autenrieth, Ingo B., Bachmann, Till T.

Invasive fungal infections have emerged as a major cause of morbidity and mortality in immunocompromised patients. Conventional identification of pathogenic fungi in clinical microbiology...

Fluorescence Lifetime Imaging of Quantum Dot Labeled DNA Microarrays

Giraud, Gerard, Schulze, Holger, Bachmann, Till T., Campbell, Colin J., R., Andrew, ...

Quantum dot (QD) labeling combined with fluorescence lifetime imaging microscopy is proposed as a powerful transduction technique for the detection of DNA hybridization events. Fluorescence lifetime...