Tillmann Cyrus

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice

Cyrus, Tillmann, Witztum, Joseph L., Rader, Daniel J., Tangirala, Rajendra, Fazio, Sergio, Linton, MacRae F., ...

Atherosclerosis may be viewed as an inflammatory disease process that includes early oxidative modification of LDLs, leading to foam cell formation. This “oxidation hypothesis” has gained general...

Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E–deficient mice

Cyrus, Tillmann, Witztum, Joseph L., Rader, Daniel J., Tangirala, Rajendra, Fazio, Sergio, Linton, MacRae F., ...

Atherosclerosis may be viewed as an inflammatory disease process that includes early oxidative modification of LDLs, leading to foam cell formation. This “oxidation hypothesis” has gained general...

Thromboxane receptor blockade improves the antiatherogenic effect of thromboxane A2 suppression in LDLR KO mice

Cyrus, Tillmann, Yao, Yuemang, Ding, Tao, Dogné, Jean Michel, Praticò, Domenico

Suppression of thromboxane (Tx) A2 biosynthesis retards atherogenesis. In this setting, the coincidental presence of nonconventional ligands for the TxA2 receptor (TP), such as isoprostanes, could...

Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics

Tran, Trung D, Caruthers, Shelton D, Hughes, Michael, Marsh, John N, Cyrus, Tillmann, Winter, Patrick M, ...

Molecular imaging is a novel tool that has allowed non-invasive diagnostic imaging to transition from gross anatomical description to identification of specific tissue epitopes and observation of...