Tim Becker

GENESTAT: an information portal for design and analysis of genetic association studies (2009)

Ripatti, Samuli, Becker, Tim, Bickeböller, Heike, Dominicus, Annica, Fischer, Christine, Humphreys, Keith, ...

This is the author's final draft of the paper published as European Journal of Human Genetics, 2009, 17 (4), pp. 533-536. The final version is available from...

A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation (2009)

El-Maarri, Osman, Kareta, Michael S., Mikeska, Thomas, Becker, Tim, Diaz-Lacava, Amalia, Junen, Judith, ...

Causes underlying inter-individual variations in DNA methylation profiles among normal healthy populations are not thoroughly understood. To investigate the contribution of genetic variation in DNA...

Genetic association analysis with FAMHAP: a major program update (2009)

Herold, Christine, Becker, Tim

Summary: FAMHAP is an established software for haplotype association analysis of nuclear families. We have released a major update that comprises various new features for case-control data....

The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations (2009)

Schumacher, Johannes, Laje, Gonzalo, Jamra, Rami Abou, Becker, Tim, Mühleisen, Thomas W., Vasilescu, Catalina, ...

Association studies, as well as the initial translocation family study, identified the gene Disrupted-In-Schizophrenia-1 (DISC1) as a risk factor for schizophrenia. DISC1 encodes a multifunctional...

Analysis and specification of an open platform for outpatient care in consideration of actual standard solutions (2008)

Rosales Saurer, Bruno, Müller-Gorchs, Mercè, Lindner, Thomas, Becker, Tim

The field of ambulatory nursing is rapidly growing due to rising health care costs and the demographic development. Today there are approximately 2 million persons in Germany who need outpatient...

The TNFalpha receptor TNFRSF1A and genes encoding the amiloride-sensitive sodium channel ENaC as modulators in cystic fibrosis (2006)

Becker, Tim, Kumar, Vinod, Jansen, Silke, ...

The CFTR mutations in cystic fibrosis (CF) lead to ion transport anomalities which predispose to chronic infection and inflammation of CF airways as the major determinants for morbidity and mortality...

Formal concept analysis and algebraic geometry /--Tim Becker. (1999)

Becker, Tim.

Thesis (doctoral) - Technische Universität, Darmstadt, 1999.

Mobile Robotics 1994 (1995)

Graduate Students, O. Fuentes, J. Karlsson, W. Meira, R. Rao, T. Riopka, ...

On 7 December 1994, four student-built autonomous robots demonstrated various strategic, tactical, and mechanical approaches to a delivery task. That event was preceded by approximately two years of...

The rochester checkers player: multimodel parallel programming for animate vision (1992)

Brian Marsh, Chris Brown, Thomas Leblanc, Michael Scott, Tim Becker, Cesar Quiroz, ...

Checkers, a complex real-time application, demonstrates the advantages of decomposing animate vision systems by function and independently selecting an appropriate ' parallel-programming model...

The DTNBP1 (Dysbindin) Gene Contributes to Schizophrenia, Depending on Family History of the Disease

Van Den Bogaert, Ann, Schumacher, Johannes, Schulze, Thomas G., Otte, Andreas C., Ohlraun, Stephanie, Kovalenko, Svetlana, ...

We have investigated the gene for dystrobrevin-binding protein 1 (DTNBP1), or dysbindin, which has been strongly suggested as a positional candidate gene for schizophrenia, in three samples of...

A Powerful Strategy to Account for Multiple Testing in the Context of Haplotype Analysis

Becker, Tim, Knapp, Michael

Haplotypes—that is, linear arrangements of alleles on the same chromosome that were inherited as a unit—are expected to carry important information in the context of association fine mapping of...

Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia

Hillmer, Axel M., Hanneken, Sandra, Ritzmann, Sibylle, Becker, Tim, Freudenberg, Jan, Brockschmidt, Felix F., ...

Androgenetic alopecia (AGA), or male-pattern baldness, is the most common form of hair loss. Its pathogenesis is androgen dependent, and genetic predisposition is the major requirement for the...