Tim Rostron

Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes (2000)

Tan, Linda C, Mowat, Alastair G, Fazou, Chrysoula, Rostron, Tim, Roskell, Helen, Dunbar, P Rod, ...

Statement of findings CD8 + T cells dominate the lymphocyte population insynovial fluid in chronic inflammatory arthritis. It is known that theseCD8 + T cells are often clonally or oligoclonally...

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes. (2000)

Tan, Linda, Mowat, Alastair, Fazou, Chrysoula, Rostron, Tim, Roskell, Helen, Dunbar, P Rod, ...

INTRODUCTION: Epstein-Barr virus (EBV) is transmitted orally, replicates in the oropharynx and establishes life-long latency in human B lymphocytes. T-cell responses to latent and lytic/replicative...

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes. (2000)

Tan, Linda, Mowat, Alastair, Fazou, Chrysoula, Rostron, Tim, Roskell, Helen, Dunbar, P Rod, ...

INTRODUCTION: Epstein-Barr virus (EBV) is transmitted orally, replicates in the oropharynx and establishes life-long latency in human B lymphocytes. T-cell responses to latent and lytic/replicative...

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes. (2000)

Tan, Linda, Mowat, Alastair, Fazou, Chrysoula, Rostron, Tim, Roskell, Helen, Dunbar, P Rod, ...

INTRODUCTION: Epstein-Barr virus (EBV) is transmitted orally, replicates in the oropharynx and establishes life-long latency in human B lymphocytes. T-cell responses to latent and lytic/replicative...

Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes. (2000)

Tan, Linda, Mowat, Alastair, Fazou, Chrysoula, Rostron, Tim, Roskell, Helen, Dunbar, P Rod, ...

INTRODUCTION: Epstein-Barr virus (EBV) is transmitted orally, replicates in the oropharynx and establishes life-long latency in human B lymphocytes. T-cell responses to latent and lytic/replicative...

Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes

Tan, Linda C, Mowat, Alastair G, Fazou , Chrysoula, Rostron , Tim, Roskell, Helen, Dunbar , P Rod, ...

CD8+ T cells dominate the lymphocyte population in synovial fluid in chronic inflammatory arthritis. It is known that these CD8+ T cells are often clonally or oligoclonally expanded, but their...

Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa

Dorrell, Lucy, Dong, Tao, Ogg, Graham S., Lister, Simon, McAdam, Steve, Rostron, Tim, ...

We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several...

Cytotoxic T Cells from Human Immunodeficiency Virus Type 2-Infected Patients Frequently Cross-React with Different Human Immunodeficiency Virus Type 1 Clades

Bertoletti, Antonio, Cham, Fatim, McAdam, Stephen, Rostron, Tim, Rowland-Jones, Sarah, Sabally, Sehu, ...

Knowledge of immune mechanisms responsible for the cross-protection between highly divergent viruses such as human immunodeficiency virus type 1 (HIV-1) and HIV-2 may contribute to an understanding...

Maternal SDF1 3′A Polymorphism Is Associated with Increased Perinatal Human Immunodeficiency Virus Type 1 Transmission

John, Grace C., Rousseau, Christine, Dong, Tao, Rowland-Jones, Sarah, Nduati, Ruth, Mbori-Ngacha, Dorothy, ...

Genetic polymorphisms in chemokine and chemokine receptor genes influence susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and disease progression, but little is known...

CD8+ T-cell selection, function, and death in the primary immune response in vivo

Callan, Margaret F.C., Fazou, Chrysoula, Yang, Hongbing, Rostron, Tim, Poon, Kathryn, Hatton, Chris, ...

The primary immune response to Epstein Barr virus (EBV) is characterized by striking proliferation of EBV-specific CD8+ T cells. In this study we have investigated the clonal composition and...

Expansion and Diversification of Virus-Specific T Cells following Immunization of Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals with a Recombinant Modified Vaccinia Virus Ankara/HIV-1 Gag Vaccine

Dorrell, Lucy, Yang, Hongbing, Ondondo, Beatrice, Dong, Tao, Di Gleria, Kati, Suttill, Annie, ...

Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. Since CD8+ and...

Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes

Tan, Linda C, Mowat, Alastair G, Fazou , Chrysoula, Rostron , Tim, Roskell, Helen, Dunbar , P Rod, ...

CD8+ T cells dominate the lymphocyte population in synovial fluid in chronic inflammatory arthritis. It is known that these CD8+ T cells are often clonally or oligoclonally expanded, but their...

Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa

Dorrell, Lucy, Dong, Tao, Ogg, Graham S., Lister, Simon, McAdam, Steve, Rostron, Tim, ...

We present detailed studies of human immunodeficiency virus (HIV)-specific cytotoxic T-lymphocyte (CTL) responses to clade A or C HIV type 1 in three donors infected in East Africa. We define several...

Cytotoxic T Cells from Human Immunodeficiency Virus Type 2-Infected Patients Frequently Cross-React with Different Human Immunodeficiency Virus Type 1 Clades

Bertoletti, Antonio, Cham, Fatim, McAdam, Stephen, Rostron, Tim, Rowland-Jones, Sarah, Sabally, Sehu, ...

Knowledge of immune mechanisms responsible for the cross-protection between highly divergent viruses such as human immunodeficiency virus type 1 (HIV-1) and HIV-2 may contribute to an understanding...

Maternal SDF1 3′A Polymorphism Is Associated with Increased Perinatal Human Immunodeficiency Virus Type 1 Transmission

John, Grace C., Rousseau, Christine, Dong, Tao, Rowland-Jones, Sarah, Nduati, Ruth, Mbori-Ngacha, Dorothy, ...

Genetic polymorphisms in chemokine and chemokine receptor genes influence susceptibility to human immunodeficiency virus type 1 (HIV-1) infection and disease progression, but little is known...

CD8+ T-cell selection, function, and death in the primary immune response in vivo

Callan, Margaret F.C., Fazou, Chrysoula, Yang, Hongbing, Rostron, Tim, Poon, Kathryn, Hatton, Chris, ...

The primary immune response to Epstein Barr virus (EBV) is characterized by striking proliferation of EBV-specific CD8+ T cells. In this study we have investigated the clonal composition and...

Expansion and Diversification of Virus-Specific T Cells following Immunization of Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals with a Recombinant Modified Vaccinia Virus Ankara/HIV-1 Gag Vaccine

Dorrell, Lucy, Yang, Hongbing, Ondondo, Beatrice, Dong, Tao, Di Gleria, Kati, Suttill, Annie, ...

Affordable therapeutic strategies that induce sustained control of human immunodeficiency virus type 1 (HIV-1) replication and are tailored to the developing world are urgently needed. Since CD8+ and...