Expression analysis of G Protein-Coupled Receptors in mouse macrophages (2008)
Lattin, Jane E, Schroder, Kate, Su, Andrew I, Walker, John R, Zhang, Jie, Wiltshire, Tim, ...
Abstract Background Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic...
Genetical Genomics: Spotlight on QTL Hotspots (2008)
Breitling, Rainer, Li, Yang, Tesson, Bruno M., Fu, Jingyuan, Wu, Chunlei, Wiltshire, Tim, ...
Labialle, Stéphane, Yang, Lanjian, Ruan, Xuan, Villemain, Aude, Schmidt, Jennifer V., Hernandez, Arturo, ...
The functioning of the genome is tightly related to its architecture. Therefore, understanding the relationship between different regulatory mechanisms and the organization of chromosomal domains is...
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse (2006)
Moran, Jennifer L., Bolton, Andrew D., Tran, Pamela V., Brown, Alison, Dwyer, Noelle D., Manning, Danielle K., ...
Phenotype-driven genetics can be used to create mouse models of human disease and birth defects. However, the utility of these mutant models is limited without identification of the causal gene. To...
Reijmers, Leon G., Coats, Jennifer K., Pletcher, Mathew T., Wiltshire, Tim, Tarantino, Lisa M., Mayford, Mark
Targeted mutagenesis in mice has shown that genes from a wide variety of gene families are involved in memory formation. The efficient identification of genes involved in learning and memory could be...
Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse (2006)
Moran, Jennifer L., Bolton, Andrew D., Tran, Pamela V., Brown, Alison, Dwyer, Noelle D., Manning, Danielle K., ...
Phenotype-driven genetics can be used to create mouse models of human disease and birth defects. However, the utility of these mutant models is limited without identification of the causal gene. To...
Bystrykh, Leonid, Weersing, Ellen, Dontje, Bert, Sutton, Sue, Pletcher, Mathew T., Wiltshire, Tim, ...
We combined large-scale mRNA expression analysis and gene mapping to identify genes and loci that control hematopoietic stem cell (HSC) function. We measured mRNA expression levels in purified HSCs...
Phillip Mcclurg, Mathew T Pletcher, Tim Wiltshire, Andrew I Su, Andrew I Su
© 2006McClurg et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Owens, Sarah E., Broman, Karl W., Wiltshire, Tim, Elmore, J. Bradford, Bradley, Kevin M., Smith, Jeffrey R., ...
Hirschsprung disease (HSCR) is a complex disorder that exhibits incomplete penetrance and variable expressivity due to interactions among multiple susceptibility genes. Studies in HSCR families have...
Owens, Sarah E., Broman, Karl W., Wiltshire, Tim, Elmore, J. Bradford, Bradley, Kevin M., Smith, Jeffrey R., ...
Hirschsprung disease (HSCR) is a complex disorder that exhibits incomplete penetrance and variable expressivity due to interactions among multiple susceptibility genes. Studies in HSCR families have...
Use of a Dense Single Nucleotide Polymorphism Map for In Silico Mapping in the Mouse (2004)
Mathew T. Pletcher, Philip McClurg, Serge Batalov, Andrew I. Su, S. Whitney Barnes, Erica Lagler, ...
Rapid expansion of available data, both phenotypic and genotypic, for multiple strains of mice has enabled the development of new methods to interrogate the mouse genome for functional genetic...
High-Resolution BAC-Based Map of the Central Portion of Mouse Chromosome 5 (2001)
Crabtree, Jonathan, Wiltshire, Tim, Brunk, Brian, Zhao, Shaying, Schug, Jonathan, Stoeckert, Christian J., ...
Wiltshire, Tim, Pletcher, Mathew, Cole, Susan E., Villanueva, Melissa, Birren, Bruce, Lehoczky, Jessica, ...
Gene Set Enrichment in eQTL Data Identifies Novel Annotations and Pathway Regulators
Wu, Chunlei, Delano, David L., Mitro, Nico, Su, Stephen V., Janes, Jeff, McClurg, Phillip, ...
Genome-wide gene expression profiling has been extensively used to generate biological hypotheses based on differential expression. Recently, many studies have used microarrays to measure gene...
Expression analysis of G Protein-Coupled Receptors in mouse macrophages
Lattin, Jane E, Schroder, Kate, Su, Andrew I, Walker, John R, Zhang, Jie, Wiltshire, Tim, ...
Genetical Genomics: Spotlight on QTL Hotspots
Breitling, Rainer, Li, Yang, Tesson, Bruno M., Fu, Jingyuan, Wu, Chunlei, Wiltshire, Tim, ...
The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6−/− mice
Cheli, Yann, Jensen, Deborah, Marchese, Patrizia, Habart, David, Wiltshire, Tim, Cooke, Michael, ...
Platelet glycoprotein VI (GPVI) is a key receptor for collagens that mediates the propagation of platelet attachment and activation. Targeted disruption of the murine gene Gp6 on a mixed 129 × 1/SvJ...
Williams, Richard, Lim, Jackie E., Harr, Bettina, Wing, Claudia, Walters, Ryan, Distler, Margaret G., ...
Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV)...
The genetic contribution to heart rate and heart rate variability in quiescent mice
Howden, Reuben, Liu, Eric, Miller-DeGraff, Laura, Keener, Heather L., Walker, Christopher, Clark, James A., ...
Recent studies have suggested a genetic component to heart rate (HR) and HR variability (HRV). However, a systematic examination of the genetic contribution to the variation in HR and HRV has not...
Schwander, Martin, Xiong, Wei, Tokita, Joshua, Lelli, Andrea, Elledge, Heather M., Kazmierczak, Piotr, ...
Deafness is the most common form of sensory impairment in humans and is frequently caused by single gene mutations. Interestingly, different mutations in a gene can cause syndromic and nonsyndromic...