Changes in microRNA expression profiles in HIV-1-transfected human cells (2005)
Yeung, Man Lung, Bennasser, Yamina, Myers, Timothy G, Jiang, Guojian, Benkirane, Monsef, Jeang, Kuan-Teh
Abstract MicroRNAs (miRNAs) are small RNAs of 18–25 nucleotides (nt) in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs...
Kelland, Lloyd R., Sharp, Swee Y., Rogers, Paul M., Myers, Timothy G., Workman, Paul
BACKGROUND: To our knowledge, 17-allylamino,17-demethoxygeldanamycin (17AAG) is the first inhibitor of heat shock protein 90 (Hsp90) to enter a phase I clinical trial in cancer. Inhibition of Hsp90,...
Leming M. Shi, Timothy G. Myers, Yi Fan, Patrick M. O’connor, Kenneth D. Paull, Stephen H. Friend, ...
The United States National Cancer Institute conducts an anticancer drug discovery program in which �10,000 compounds are screened every year in vitro against a panel of 60 human cancer cell lines...
Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin
Carrier, France, Georgel, Philippe T., Pourquier, Philippe, Blake, Mellissa, Kontny, H. Udo, Antinore, Michael J., ...
This report demonstrates that Gadd45, a p53-responsive stress protein, can facilitate topoisomerase relaxing and cleavage activity in the presence of core histones. A correlation between reduced...
Carbonic Anhydrase III Is Not Required in the Mouse for Normal Growth, Development, and Life Span
Kim, Geumsoo, Lee, Tae-Hoon, Wetzel, Petra, Geers, Cornelia, Robinson, Mary Ann, Myers, Timothy G., ...
Carbonic anhydrase III is a cytosolic protein which is particularly abundant in skeletal muscle, adipocytes, and liver. The specific activity of this isozyme is quite low, suggesting that its...
Changes in microRNA expression profiles in HIV-1-transfected human cells
Yeung, Man Lung, Bennasser, Yamina, Myers, Timothy G, Jiang, Guojian, Benkirane, Monsef, Jeang, Kuan-Teh
MicroRNAs (miRNAs) are small RNAs of 18–25 nucleotides (nt) in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs may...
Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin
Carrier, France, Georgel, Philippe T., Pourquier, Philippe, Blake, Mellissa, Kontny, H. Udo, Antinore, Michael J., ...
This report demonstrates that Gadd45, a p53-responsive stress protein, can facilitate topoisomerase relaxing and cleavage activity in the presence of core histones. A correlation between reduced...
Carbonic Anhydrase III Is Not Required in the Mouse for Normal Growth, Development, and Life Span
Kim, Geumsoo, Lee, Tae-Hoon, Wetzel, Petra, Geers, Cornelia, Robinson, Mary Ann, Myers, Timothy G., ...
Carbonic anhydrase III is a cytosolic protein which is particularly abundant in skeletal muscle, adipocytes, and liver. The specific activity of this isozyme is quite low, suggesting that its...
Changes in microRNA expression profiles in HIV-1-transfected human cells
Yeung, Man Lung, Bennasser, Yamina, Myers, Timothy G, Jiang, Guojian, Benkirane, Monsef, Jeang, Kuan-Teh
MicroRNAs (miRNAs) are small RNAs of 18–25 nucleotides (nt) in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs may...