Tina Graves

Sequencing human-gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites (2009)

Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, ...

The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of...

Higher-order genome organization in platypus and chicken sperm and repositioning of sex chromosomes during mammalian evolution (2009)

Tsend-Ayush, Enkhjargal, Dodge, Natasha Chantelle Louise, Mohr, Julia, Casey, Aaron Edward, Himmelbauer, Heinz, Kremitzki, Colin L., ...

Enkhjargal Tsend-Ayush, Natasha Dodge, Julia Mohr, Aaron Casey, Heinz Himmelbauer, Colin L. Kremitzki, Kyriena Schatzkamer, Tina Graves, Wesley C. Warren and Frank Grützner

Higher-order genome organization in platypus and chicken sperm and repositioning of sex chromosomes during mammalian evolution (2009)

Tsend-Ayush, Enkhjargal, Dodge, Natasha Chantelle Louise, Mohr, Julia, Casey, Aaron Edward, Himmelbauer, Heinz, Kremitzki, Colin L., ...

Enkhjargal Tsend-Ayush, Natasha Dodge, Julia Mohr, Aaron Casey, Heinz Himmelbauer, Colin L. Kremitzki, Kyriena Schatzkamer, Tina Graves, Wesley C. Warren and Frank Grützner

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals (2008)

Patel, Vidushi S, Cooper, Steven JB, Deakin, Janine E, Fulton, Bob, Graves, Tina, Warren, Wesley C, ...

Abstract Background Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin...

Genome analysis of the platypus reveals unique signatures of evolution (2008)

Warren, Wesley C., Hillier, LaDeana W., Marshall Graves, Jennifer A., Birney, Ewan, Ponting, Chris P., Grützner, Frank, ...

We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a...

Haplotype sorting using human fosmid clone end-sequence pairs (2008)

Kidd, Jeffrey M., Cheng, Ze, Graves, Tina, Fulton, Bob, Wilson, Richard K., Eichler, Evan E.

An important goal of human genetics and genomics is to understand the complete spectrum of genetic variation across a specific human haplotype. By combining information from a dense SNP map with...

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals (2008)

Patel, Vidushi S., Cooper, Steven John Baynard, Deakin, Janine E., Fulton, Bob, Graves, Tina, Warren, Wesley, ...

Background: Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the...

Platypus globin genes and flanking loci suggest a new insertional model for beta-globin evolution in birds and mammals (2008)

Patel, Vidushi S., Cooper, Steven John Baynard, Deakin, Janine E., Fulton, Bob, Graves, Tina, Warren, Wesley, ...

Background: Vertebrate alpha (α)- and beta (β)-globin gene families exemplify the way in which genomes evolve to produce functional complexity. From tandem duplication of a single globin locus, the...

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome (2007)

Margulies, Elliott H., Cooper, Gregory M., Asimenos, George, Thomas, Daryl J., Dewey, Colin N., Siepel, Adam, ...

A key component of the ongoing ENCODE project involves rigorous comparative sequence analyses for the initially targeted 1% of the human genome. Here, we present orthologous sequence generation,...

Integrated and sequence-ordered BAC and YAC-based physical maps for the rat genome (2004)

Krzywinski,Martin, Wallis,John, Goesele,Claudia, Bosdet,Ian, Chiu,Readman, Graves,Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Integrated and sequence-ordered BAC and YAC-based physical maps for the rat genome (2004)

Krzywinski,Martin, Wallis,John, Goesele,Claaudia, Bosdet,Ian, Chiu,Readman, Graves,Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Integrated and sequence-ordered BAC and YAC-based physical maps for the rat genome (2004)

Krzywinski, Martin, Wallis, John, Goesele, Claaudia, Bosdet, Ian, Chiu, Readman, Graves, Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Integrated and sequence-ordered BAC and YAC-based physical maps for the rat genome (2004)

Krzywinski, Martin, Wallis, John, Goesele, Claudia, Bosdet, Ian, Chiu, Readman, Graves, Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Integrated and Sequence-Ordered BAC- and YAC-Based Physical Maps for the Rat Genome (2004)

Krzywinski, Martin, Wallis, John, Gösele, Claudia, Bosdet, Ian, Chiu, Readman, Graves, Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Integrated and Sequence-Ordered BAC- and YAC-Based Physical Maps for the Rat Genome

Krzywinski, Martin, Wallis, John, Gösele, Claudia, Bosdet, Ian, Chiu, Readman, Graves, Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Integrated and Sequence-Ordered BAC- and YAC-Based Physical Maps for the Rat Genome

Krzywinski, Martin, Wallis, John, Gösele, Claudia, Bosdet, Ian, Chiu, Readman, Graves, Tina, ...

As part of the effort to sequence the genome of Rattus norvegicus, we constructed a physical map comprised of fingerprinted bacterial artificial chromosome (BAC) clones from the CHORI-230 BAC...

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

Margulies, Elliott H., Cooper, Gregory M., Asimenos, George, Thomas, Daryl J., Dewey, Colin N., Siepel, Adam, ...

A key component of the ongoing ENCODE project involves rigorous comparative sequence analyses for the initially targeted 1% of the human genome. Here, we present orthologous sequence generation,...

Defensins and the convergent evolution of platypus and reptile venom genes

Whittington, Camilla M., Papenfuss, Anthony T., Bansal, Paramjit, Torres, Allan M., Wong, Emily S.W., Deakin, Janine E., ...

When the platypus (Ornithorhynchus anatinus) was first discovered, it was thought to be a taxidermist’s hoax, as it has a blend of mammalian and reptilian features. It is a most remarkable mammal,...

Lineage-Specific Biology Revealed by a Finished Genome Assembly of the Mouse

Church, Deanna M., Goodstadt, Leo, Hillier, LaDeana W., Zody, Michael C., Goldstein, Steve, She, Xinwe, ...

A finished clone-based assembly of the mouse genome reveals extensive recent sequence duplication during recent evolution and rodent-specific expansion of certain gene families. Newly assembled...

Haplotype sorting using human fosmid clone end-sequence pairs

Kidd, Jeffrey M., Cheng, Ze, Graves, Tina, Fulton, Bob, Wilson, Richard K., Eichler, Evan E.

An important goal of human genetics and genomics is to understand the complete spectrum of genetic variation across a specific human haplotype. By combining information from a dense SNP map with...

Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

Girirajan, Santhosh, Chen, Lin, Graves, Tina, Marques-Bonet, Tomas, Ventura, Mario, Fronick, Catrina, ...

The gibbon genome exhibits extensive karyotypic diversity with an increased rate of chromosomal rearrangements during evolution. In an effort to understand the mechanistic origin and implications of...