Ting Chen

Publication List Details

Period

1982 - 2009

Number

185

Co-Authors

The Case for a Structured Approach to Managing Unstructured Data (2009)

Anhai Doan, Jeffrey F. Naughton, Akanksha Baid, Xiaoyong Chai, Fei Chen, Ting Chen, ...

The challenge of managing unstructured data represents perhaps the largest data management opportunity for our community since managing relational data. And yet we are risking letting this...

The Case for a Structured Approach to Managing Unstructured Data (2009)

Doan, AnHai, Naughton, Jeff, Baid, Akanksha, Chai, Xiaoyong, Chen, Fei, Chen, Ting, ...

The challenge of managing unstructured data represents perhaps the largest data management opportunity for our community since managing relational data. And yet we are risking letting this...

Seismic attenuation structure in central Mexico: Image of a focused high-attenuation zone in the mantle wedge (2009)

Chen, Ting, Clayton, Robert W.

Velocity spectra from moderate-sized earthquakes were used to investigate the P wave attenuation structure in central Mexico. In particular, we included regional events with magnitudes in the range...

Am. J. Hum. Genet. 73:63–73, 2003 Haplotype Block Partition with Limited Resources and Applications (2009)

Kui Zhang, Fengzhu Sun, Michael S. Waterman, Ting Chen

Recent studies have shown that the human genome has a haplotype block structure such that it can be decomposed into large blocks with high linkage disequilibrium (LD) and relatively limited haplotype...

On the Provenance of Non-Answers to Queries over Extracted Data ∗ ABSTRACT (2009)

Jiansheng Huang, Ting Chen, Anhai Doan, Jeffrey F. Naughton

In information extraction, uncertainty is ubiquitous. For this reason, it is useful to provide users querying extracted data with explanations for the answers they receive. Providing the provenance...

Scaling of small repeating earthquakes explained by interaction of seismic and aseismic slip in a rate and state fault model (2009)

Chen, Ting, Lapusta, Nadia

Because of short recurrence times and known locations, small repeating earthquakes present a rare predictable opportunity for detailed field observations. They are used to study fault creeping...

MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages (2009)

Chen, Ting, Huang, Zhouqing, Wang, Liansheng, Wang, Yue, Wu, Feizhen, Meng, Shu, ...

Aims The inflammatory responses of monocytes/macrophages and the stimulation of lipid uptake into these cells by oxidized low density lipoprotein (oxLDL) are critical to the initiation and...

PerM: efficient mapping of short sequencing reads with periodic full sensitive spaced seeds (2009)

Chen, Yangho, Souaiaia, Tade, Chen, Ting

Motivation: The explosion of next-generation sequencing data has spawned the design of new algorithms and software tools to provide efficient mapping for different read lengths and sequencing...

Handling Constraints in Multi-Objective GA for Embedded System Design (2008)

Biman Chakraborty, Ting Chen, Tulika Mitra, Abhik Roychoudhury

Design space exploration is central to embedded system design. Typically this is a multi-objective search problem, where performance, power, area etc. are the different optimization criteria, to find...

General Terms (2008)

Vivy Suhendra, Tulika Mitra, Abhik Roychoudhury, Ting Chen

Accurate estimation of the worst-case execution time (WCET) of a program is important for real-time embedded software. Static WCET estimation involves program path analysis and architectural...

Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy (2008)

Wang, Li, Sun, Fengzhu, Chen, Ting

Abstract We have developed a global strategy based on the Bayesian network framework to prioritize the functional modules mediating genetic perturbations and their phenotypic effects among a set of...

Bioinformatics Advance Access published January 19, 2007 (2008)

Debojyoti Dutta, Ting Chen

Fig. 1. Overall idea of our method. Spectra are mapped into high dimensional points and so are hypothetical spectra generated from peptide sequences. To speed up database search, the one-against-all...

A critical assessment of Mus musculusgene function prediction using integrated genomic evidence (2008)

Peña-Castillo, Lourdes, Tasan, Murat, Myers, Chad L, Lee, Hyunju, Joshi, Trupti, Zhang, Chao, ...

Abstract Background: Several years after sequencing the human genome and the mouse genome, much remains to be discovered about the functions of most human and mouse genes. Computational prediction of...

Journal of Computational Biology, 10(1):1-12, 2003 A Suboptimal Algorithm for De Novo Peptide Sequencing via Tandem Mass Spectrometry (2008)

Bingwen Lu, Ting Chen

Tandem mass spectrometry has emerged to be one of the most powerful high-throughput techniques for protein identification. Tandem mass spectrometry selects and fragments peptides of interest into...

H O (2008)

Ting Chen, Ming-yang Kao, Matthew Tepel, John Rush, George M. Church

Tandem mass spectrometry fragments a large number of molecules of the same peptide sequence into charged molecules of prefix and suffix peptide subsequences, and then measures mass/charge ratios of...

A hidden markov model based scoring function for tandem mass spectrometry (2008)

Yunhu Wan, Austin Yang, Ting Chen

An accurate scoring function for database search is crucial for peptide identification using tandem mass spectrometry. Although many mathematical models have been proposed to score peptides against...

On the Informational Asymmetry between Upper and Lower Bounds for Ultrametric Evolutionary Trees (2008)

Ting Chen

Abstract. This paper addresses the informational asymmetry for constructing an ultrametric evolutionary tree from upper and lower bounds on pairwise distances between n given species. We show that...

Integrating Shape and Texture in Deformable Models: from Hybrid Methods to Metamorphs (2008)

Dimitris Metaxas, Xiaolei Huang, Ting Chen

Abstract. In traditional shape-based deformable models, the external image forces come primarily from edge or gradient information. Such reliance on edge information, however, makes the models prone...

Pacific Symposium on Biocomputing 8:140-151(2003) ASSESSMENT OF THE RELIABILITY OF PROTEIN-PROTEIN INTERACTIONS AND PROTEIN FUNCTION PREDICTION (2008)

M. Deng, F. Sun, T. Chen, Minghua Deng, Fengzhu Sun, Ting Chen

As more and more high-throughput protein-protein interaction data are collected, the task of estimating the reliability of different data sets becomes increasingly important. In this paper, we...

On View Transformation Support for a Native XML DBMS (2008)

Daofeng Luo, Ting Chen, Tok Wang Ling, Xiaofeng Meng

Abstract. XML is becoming the standard data exchange format. View or transformation of XML data is important and frequent operation in XML data integration and publishing. In schema-based view...

On View Transformation Support for a Native XML DBMS (2008)

Daofeng Luo, Ting Chen, Tok Wang Ling, Xiaofeng Meng

Abstract. XML is becoming the standard data exchange format. View transformation of XML data is important and frequent operation in XML data integration and publishing. In schema-based view...

General Terms (2008)

Vivy Suhendra, Tulika Mitra, Abhik Roychoudhury, Ting Chen

Accurate estimation of the worst-case execution time (WCET) of a program is important for real-time embedded software. Static WCET estimation involves program path analysis and architectural...

Techniques for Gigabyte-Scale N-gram Based (2008)

Information Retrieval On, Ethan Miller, Dan Shen, Junli Liu, Charles Nicholas, Ting Chen

this paper, we discuss the implementation techniques that allowed us to use n-gram based retrieval methods on a gigabyte corpus on commodity personal computer hardware. While such techniques have...

Jaceosidin Induces Apoptosis in Human Ovary Cancer Cells through Mitochondrial Pathway (2008)

Wen Lv, Xia Sheng, Ting Chen, Qiang Xu, Xing Xie

We examined the antiproliferation effect of Jaceosidin (4′, 5, 7-trihydroxy-3′, 6-dimethoxyflavone) isolated from the herb of Artemisia vestita Wall on several human cancer cell lines. Jaceosidin...

Techniques for Gigabyte-Scale N-gram Based Information Retrieval on Personal Computers (2007)

Ethan Miller Dan, Dan Shen, Junli Liu, Charles Nicholas, Ting Chen

this paper, we discuss the implementation techniques that allowed us to use n-gram based retrieval methods on a gigabyte corpus on commodity personal computer hardware. While such techniques have...

Assessment of the Reliability of Protein-Protein Interactions and (2007)

Protein Function Prediction, Minghua Deng, Fengzhu Sun, Ting Chen

As more and more high-throughput protein-protein interaction data are collected, the task of estimating the reliability of di#erent data sets becomes increasingly important. In this paper, we present...

Speeding up tandem mass spectrometry database search: metric embeddings and fast near neighbor search (2007)

Dutta, Debojyoti, Chen, Ting

Motivation: Due to the recent advances in technology of mass spectrometry, there has been an exponential increase in the amount of data being generated in the past few years. Database searches have...

Simulation studies of a phenomenological model for elongated virus capsid formation (2007)

Chen, Ting, Glotzer, Sharon C.

We study a phenomenological model in which the simulated packing of hard, attractive spheres on a prolate spheroid surface with convexity constraints produces structures identical to those of prolate...

Computer simulation and human experiment on the Laplacian electrocardiogram (ECG) / (2007)

Chen, Ting.

Thesis (Ph.D. in Biomedical Engineering) -- Louisiana Tech University, August 2007.

A relational approach to incrementally extracting and querying structure in unstructured data (2007)

Eric Chu, Akanksha Baid, Ting Chen, Anhai Doan, Jeffrey Naughton

There is a growing consensus that it is desirable to query over the structure implicit in unstructured documents, and that ideally this capability should be provided incrementally. However, there is...

A relational approach to incrementally extracting and querying structure in unstructured data (2007)

Eric Chu, Akanksha Baid, Ting Chen, Anhai Doan, Jeffrey Naughton

There is a growing consensus that it is desirable to query over the structure implicit in unstructured documents, and that ideally this capability should be provided incrementally. However, there is...

Exploiting Branch Constraints without Exhaustive Path Enumeration (2007)

Chen, Ting, Mitra, Tulika, Roychoudhury, Abhik, Suhendra, Vivy

Statically estimating the worst case execution time (WCET) of a program is important for real-time software. This is difficult even in the programming language level due to the inherent difficulty in...

Pressure dependence of superconductivity in doped two-leg ladder cuprates (2006)

Qin, Jihong, Chen, Ting, Feng, Shiping

Within the kinetic energy driven superconducting mechanism, the effect of the pressure on superconductivity in doped two-leg ladder cuprates is studied. It is shown that the superconducting...

Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy (2006)

Jiang, Rui, Yang, Hua, Sun, Fengzhu, Chen, Ting

Abstract Background Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have been developed...

Simulation studies of the self-assembly of cone-shaped particles (2006)

Chen, Ting, Zhang, Zhenli, Glotzer, Sharon C.

We systematically investigate the self-assembly of anisotropic cone-shaped particles decorated by ring-like attractive patches. We demonstrate that the self-assembled clusters, which arise due to the...

Simulation Studies of A Phenomenological Model for the Assembly of Elongated Virus Capsids (2006)

Chen, Ting, Glotzer, Sharon C.

We extend our previously developed general approach (1) to study a phenomenological model in which the simulated packing of hard, attractive spheres on a prolate spheroid surface with convexity...

A Precise Packing Sequence for Self-Assembled Convex Structures (2006)

Chen, Ting, Zhang, Zhenli, Glotzer, Sharon C.

Molecular simulations of the self-assembly of cone-shaped particles with specific, attractive interactions are performed. Upon cooling from random initial conditions, we find that the cones self...

An integrated approach to the prediction of domain-domain interactions (2006)

Lee, Hyunju, Deng, Minghua, Sun, Fengzhu, Chen, Ting

Abstract Background The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been made to...

Mining Mass Spectra: Metric Embeddings and Fast Near Neighbor Search (2006)

Dutta, Debojyoti, Chen, Ting

Mining large-scale high-throughput tandem mass spectrometry data sets is a very important problem in mass spectrometry based protein identification. One of the fundamental problems in large scale...

Further understanding human disease genes by comparing with housekeeping genes and other genes (2006)

Tu, Zhidong, Wang, Li, Xu, Min, Zhou, Xianghong, Chen, Ting, Sun, Fengzhu

Abstract Background Several studies have compared various features of heritable disease genes with other so called non-disease genes, but they have yielded some conflicting results. A potential...

An integrative approach for causal gene identification and gene regulatory pathway inference (2006)

Tu, Zhidong, Wang, Li, Arbeitman, Michelle N., Chen, Ting, Sun, Fengzhu

Motivation: Gene expression variation can often be linked to certain chromosomal regions and are tightly associated with phenotypic variation such as disease conditions. Inferring the causal genes...

annealing bump hunting strategy (2006)

Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen

Searching for interpretable rules for disease mutations: a simulated

Selecting additional tag SNPs for tolerating missing data in genotyping (2005)

Huang, Yao-Ting, Zhang, Kui, Chen, Ting, Chao, Kun-Mao

Abstract Background Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag SNPs) is...

From region encoding to extended Dewey: on efficient processing of XML twig pattern matching (2005)

LU, Jiaheng, LING, Tok Wang, CHAN, Chee-Yong, CHEN, Ting

Finding all the occurrences of a twig pattern in an XML database is a core operation for efficient evaluation of XML queries. A number of algorithms have been proposed to process a twig query based...

Impact of Security Measures on the Usefulness of Knowledge Management Systems (2005)

Chen, Ting

Knowledge Management (KM) has been recognized as a critical management strategy in generating competitive advantage for the organization. In order to protect organizational knowledge stored in or...

Dendritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors (2005)

Chen, Ting

(Uncorrected OCR) Abstract of thesis entitled �endritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors�Submitted by Ting Chen for the degree of Master of Philosophy...

Dendritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors (2005)

Chen, Ting

(Uncorrected OCR) Abstract of thesis entitled �endritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors�Submitted by Ting Chen for the degree of Master of Philosophy...

Dendritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors (2005)

Chen, Ting

(Uncorrected OCR) Abstract of thesis entitled �endritic cell biology regulated by Epstein-Barr virus (EBV) and its associated tumors�Submitted by Ting Chen for the degree of Master of Philosophy...

An approximation algorithm for haplotype inference by maximum parsimony (2005)

Yao-ting Huang, Kun-mao Chao, Kun-mao Chao, Ting Chen, Ting Chen

This paper studies haplotype inference by maximum parsimony using population data. We define the optimal haplotype inference (OHI) problem as given a set of genotypes and a set of related haplotypes,...

From region encoding to extended dewey: On efficient processing of xml twig pattern matching (2005)

Jiaheng Lu, Tok Wang Ling, Chee-yong Chan, Ting Chen

Finding all the occurrences of a twig pattern in an XML database is a core operation for efficient evaluation of XML queries. A number of algorithms have been proposed to process a twig query based...

WCET centric data allocation to scratchpad memory (2005)

Vivy Suhendra, Tulika Mitra, Abhik Roychoudhury, Ting Chen

Scratchpad memory is a popular choice for on-chip storage in real-time embedded systems. The allocation of code/data to scratchpad memory is performed at compile time leading to predictable memory...

From region encoding to extended dewey: On efficient processing of xml twig pattern matching (2005)

Jiaheng Lu, Tok Wang Ling, Chee-yong Chan, Ting Chen, Jaffar Joxan, Jiaheng Lu, ...

article, which has been submitted for publication in a journal or for consider-ation by the commissioning organization. The report represents the ideas of its author, and should not be taken as the...

Exploiting branch constraints without exhaustive path enumeration (2005)

Ting Chen, Tulika Mitra, Abhik Roychoudhury, Vivy Suhendra

Statically estimating the worst case execution time (WCET) of a program is important for real-time software. This is difficult even in the programming language level due to the inherent difficulty in...

BIOINFORMATICS ORIGINAL PAPER Genetics and population analysis Inference of missing SNPs and information quantity measurements for haplotype blocks (2005)

Shih-chieh Su, Ting Chen

Motivation: Missing data in genotyping single nucleotide polymorphism (SNP) spots are common. High-throughput genotyping methods usually have a high rate of missing data. For example, the published...

An approximation algorithm for haplotype inference by maximum parsimony (2005)

Yao-ting Huang, Kun-mao Chao, Ting Chen

This paper studies haplotype inference by maximum parsimony using population data. We define the optimal haplotype inference (OHI) problem as given a set of genotypes and a set of related haplotypes,...

From Region Encoding To Extended Dewey: On Efficient Processing of XML Twig Pattern Matching (2005)

Jiaheng Lu, Tok Wang Ling, Chee-Yong Chan, Ting Chen, Ling Chee-yong, Chan Ting Chen

Finding all the occurrences of a twig pattern in an XML database is a core operation for efficient evaluation of XML queries. A number of algorithms have been proposed to process a twig query based...

On Boosting Holism in XML Twig Pattern Matching Using Structural Indexing Techniques (2005)

Ting Chen, Jiaheng Lu, Tok Wang Ling

Searching for all occurrences of a twig pattern in an XML document is an important operation in XML query processing. Recently a holistic method TwigStack [2] has been proposed. The method avoids...

TJFast: Effective Processing of XML Twig Pattern Matching (2005)

Jiaheng Lu, Ting Chen, Tok Wang Ling

Finding all the occurrences of a twig pattern in an XML database is a core operation for e#cient evaluation of XML queries. A number of algorithms have been proposed to process a twig query based on...

TJFast: Effective Processing of XML Twig Pattern Matching (2005)

Jiaheng Lu, Ting Chen, Tok Wang Ling

Finding all the occurrences of a twig pattern in an XML database is a core operation for e#cient evaluation of XML queries. A number of algorithms have been proposed to process a twig query based on...

On Boosting Holism in XML Twig Pattern Matching using Structural Indexing Techniques (2005)

Ting Chen, Jiaheng Lu, Tok Wang Ling

Searching for all occurrences of a twig pattern in an XML document is an important operation in XML query processing. Recently a holistic method T wigStack [2] has been proposed. The method avoids...

WCET centric data allocation to scratchpad memory (2005)

Vivy Suhendra, Tulika Mitra, Abhik Roychoudhury, Ting Chen

Scratchpad memory is a popular choice for on-chip storage in real-time embedded systems. The allocation of code/data to scratchpad memory is performed at compile time leading to predictable memory...

Inference of missing SNPs and information quantity measurements for haplotype blocks (2005)

Su, Shih-Chieh, Kuo, C.-C. Jay, Chen, Ting

Motivation: Missing data in genotyping single nucleotide polymorphism (SNP) spots are common. High-throughput genotyping methods usually have a high rate of missing data. For example, the published...

HapBlock: haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms (2005)

Zhang, Kui, Qin, Zhaohui, Chen, Ting, Liu, Jun S., Waterman, Michael S., Sun, Fengzhu

Summary: Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed with regions of low LD. Such LD patterns make it...

Inference of missing SNPs and information quantity measurements for haplotype blocks (2005)

Su, Shih-Chieh, Kuo, C.-C. Jay, Chen, Ting

Motivation: Missing data in genotyping single nucleotide polymorphism (SNP) spots are common. High-throughput genotyping methods usually have a high rate of missing data. For example, the published...

TJFast: Efficient Processing of XML Twig Pattern Matching (2004)

LU, Jiaheng, CHEN, Ting, LING, Tok Wang

Finding all the occurrences of a twig pattern in an XML database is a core operation for efficient evaluation of XML queries. Previous twig join algorithms were proposed as an I/O optimal solution...

Prefix path streaming: A new clustering method for optimal holistic XML twig pattern matching (2004)

Ting Chen, Tok Wang Ling, Chee-yong Chan

Abstract. Searching for all occurrences of a twig pattern in a XML document is an important operation in XML query processing. Recently a class of holistic twig pattern matching algorithms has been...

Efficient Processing of XML Twig Patterns with Parent Child Edges: A Look-ahead Approach (2004)

Jiaheng Lu, Ting Chen, Tok Wang Ling

With the growin importan ce of semi-structure data in in - formation exchan e, much research has been don to provide an e#ective mechan ism to match a twig queryin an XML database. An umber of...

Efficient processing of xml twig patterns with parent child edges: a look-ahead approach (2004)

Jiaheng Lu, Ting Chen, Tok Wang Ling

With the growing importance of semi-structure data in information exchange, much research has been done to provide an effective mechanism to match a twig query in an XML database. A number of...

Prefix path streaming: A new clustering method for optimal holistic XML twig pattern matching (2004)

Ting Chen, Tok Wang Ling, Chee-yong Chan

Abstract. Searching for all occurrences of a twig pattern in a XML document is an important operation in XML query processing. Recently a class of holistic twig pattern matching algorithms has been...

Integrated Probabilistic Model for Functional Prediction of (2004)

Proteins Minghua Deng, Minghua Deng, Ting Chen, Fengzhu Sun

We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data and domain structures of...

Metamorphs: Deformable shape and texture models (2004)

Xiaolei Huang, Dimitris Metaxas, Ting Chen

We present a new class of deformable models, Meta-Morphs, whose formulation integrates both shape and interior texture. The model deformations are derived from both boundary and region information...

The Block Partitioning Results Using Different � and � a (2004)

Kui Zhang, Zhaohui S. Qin, Jun S. Liu, Ting Chen, Michael S. Waterman, Fengzhu Sun, ...

service This article cites 49 articles, 10 of which can be accessed free at:

Mapping gene ontology to proteins based on protein-protein interaction data (2004)

Deng, Minghua, Tu, Zhidong, Sun, Fengzhu, Chen, Ting

Motivation: Gene Ontology Consortium (GO) provides structural description of protein function that is used as a common language for gene annotation in many organisms. Large-scale techniques have...

HapBlock: haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms (2004)

Zhang, Kui, Qin, Zhaohui, Chen, Ting, Liu, Jun S., Waterman, Michael S., Sun, Fengzhu

Summary: Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. Such LD patterns make it...

Mapping gene ontology to proteins based on protein-protein interaction data (2004)

Deng, Minghua, Tu, Zhidong, Sun, Fengzhu, Chen, Ting

Motivation: Gene Ontology (GO) consortium provides structural description of protein function that is used as a common language for gene annotation in many organisms. Large-scale techniques have...

Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies (2004)

Zhang, Kui, Qin, Zhaohui S., Liu, Jun S., Chen, Ting, Waterman, Michael S., Sun, Fengzhu

Recent studies have revealed that linkage disequilibrium(LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs)...

Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies (2004)

Zhang, Kui, Qin, Zhaohui S., Liu, Jun S., Chen, Ting, Waterman, Michael S., Sun, Fengzhu

Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs)...

Mapping gene ontology to proteins based on protein-protein interaction data (2004)

Deng, Minghua, Tu, Zhidong, Sun, Fengzhu, Chen, Ting

Motivation: Gene Ontology Consortium (GO) provides structural description of protein function that is used as a common language for gene annotation in many organisms. Large-scale techniques have...

HapBlock: haplotype block partitioning and tag SNP selection software using a set of dynamic programming algorithms (2004)

Zhang, Kui, Qin, Zhaohui, Chen, Ting, Liu, Jun S., Waterman, Michael S., Sun, Fengzhu

Summary: Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. Such LD patterns make it...

Integration of the Gibbs prior model, the marching cubes method and the deformable model in medical image segmentation (2003)

Chen, Ting

Medical image segmentation is the process that defines the region of interest in the image volume. It is the basis of high-level image analysis such as registration, motion analyses. However, as of...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

The Role of Src Tyrosine Kinase Signaling Networks in the Development and Progression of Ovarian Cancer in a Mouse Model (2003)

Taylor, Christopher C., Chen, Ting

Ovarian cancer is among the most common and deadly malignancies in women, accounting for nearly 15,000 deaths per year in the United States. We have developed a mouse model of ovarian cancer, which...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Chen, Ting

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical properties of nickel and cobalt sulphate solutions of hydrometallurgical relevance (2003)

Chen, Ting

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Assessment of the reliability of protein–protein interactions and protein function prediction (2003)

Minghua Deng, Fengzhu Sun, Ting Chen

As more and more high-throughput protein-protein interaction data are collected, the task of estimating the reliability of different data sets becomes increasingly important. In this paper, we...

Prediction of protein function using protein-protein interaction data (2003)

Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, Fengzhu Sun

Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene expression...

Dynamic Programming Algorithms for Haplotype Block Partitioning: Applications to Human Chromosome 21 Haplotype Data (2003)

Kui Zhang, Fengzhu Sun, Michael S. Waterman, Ting Chen

Recent studies have shown that the human genome has a haplotype block structure such that it can be divided into discrete blocks of limited haplotype diversity. Patil et al. [6] and Zhang et al. [12]...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

A suffix tree approach to the interpretation of tandem mass spectra: applications to peptides of non-specific digestion and post-translational modifications (2003)

Lu, Bingwen, Chen, Ting

Motivation: Tandem mass spectrometry combined with sequence database searching is one of the most powerful tools for protein identification. As thousands of spectra are generated by a mass...

Physicochemical Properties of Nickel and Cobalt Sulphate Solutions of Hydrometallurgical Relevance (2003)

Ting Chen

Producing nickel and cobalt metal by high pressure acid leaching (HPAL) of nickel laterites is becoming one of Australia's largest mineral processing industries. However, the background chemical...

Optimal Scheduling of Capture Times in a Multiple (2002)

Capture Imaging System, Ting Chen, Abbas El Gamal

Several papers have discussed the idea of extending image sensor dynamic range by capturing several images during a normal exposure time. Most of these papers assume that the images are captured...

Prediction of Protein Function Using Protein-Protein Interaction Data (2002)

Minghua Deng Kui, Kui Zhang, Shipra Mehta, Ting Chen, Fengzhu Sun

Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene expression...

A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry (2001)

Chen, Ting, Kao, Ming-Yang, Tepel, Matthew, Rush, John, Church, George M.

The tandem mass spectrometry fragments a large number of molecules of the same peptide sequence into charged prefix and suffix subsequences, and then measures mass/charge ratios of these ions. The de...

A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry (2001)

Ting Chen, Ming-yang Kao, Matthew Tepel, John Rush, George M. Church

Tandem mass spectrometry fragments a large number of molecules of the same peptide sequence into charged molecules of pre � x and suf � x peptide subsequences and then measures mass/charge ratios...

Vector color filter array demosaicing (2001)

Maya R. Gupta, Ting Chen

Single-sensor digital cameras spatially sample the incoming image using a color filter array (CFA). Consequently, each pixel only contains a single color value. In order to reconstruct the original...

Towards a more complete understanding of cloud radiative effects (2000)

Chen, Ting

Radiative flux changes induced by the occurrence of different cloud types are investigated using ISCCP cloud data and a refined radiative transfer model from NASA/GISS GCM. Cloud-type variations are...

How small should pixel size be (2000)

Ting Chen, Peter Catrysse, Abbas E Gamal, Brian W

Pixel design is a key part of image sensor design. After deciding on pixel architecture, a fundamental tradeoff is made to select pixel size. A small pixel size is desirable because it results in a...

A Case Study in Genome-level Fragment Assembly (2000)

Ting Chen, Steven S. Skiena

Motivation: We use the fact of two teams independently sequencing the one megabase genome of Borrelia burgdorferi as an opportunity to study the accuracy of genome-level assembly. Results: We compare...

A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry (Extended Abstract) (2000)

T. Chen, Ting Chen, Ming-yang Kao, Matthew Tepel, John Rush, George M. Church

) Ting Chen Ming-Yang Kao y Matthew Tepel z John Rush x George M. Church -- Abstract The tandem mass spectrometry fragments molecules of the same peptide sequence into charged prefix and suffix...

How small should pixel size be (2000)

Ting Chen, Peter Catrysse, Brian W

Pixel design is a key part of image sensor design. After deciding on pixel architecture, a fundamental tradeoff is made to select pixel size. A small pixel size is desirable because it results in a...

How small should pixel size be (2000)

Ting Chen, Peter Catrysse, Abbas El Gamal, Brian W

Pixel design is a key part of image sensor design. After deciding on pixel architecture, a fundamental tradeoff is made to select pixel size. A small pixel size is desirable because it results in a...

A case study in genome-level fragment assembly (2000)

Chen, Ting, Skiena, Steven S.

Motivation: We use the fact of two teams independently sequencing the one megabase genome of Borrelia burgdorferi as an opportunity to study the accuracy of genome-level assembly. Results: We compare...

Modeling gene expression with differential equations (1999)

Ting Chen, Hongyu L. He, George M. Church

We propose a di erential equation model for gene expression and provide two methods to construct the model from a set of temporal data. We model both transcription and translation by kinetic...

Identifying Gene Regulatory Networks from Experimental Data (1999)

Ting Chen, Vladimir Filkov, Steven S. Skiena

this paper, we propose a methodology for making sense of large, multiple time-series data sets arising in expression analysis, and evaluate it both theoretically and through a case study. First, we...

On the Informational Asymmetry between Upper and Lower Bounds for Ultrametric Evolutionary Trees (1999)

Ting Chen, Ming-Yang Kao

. This paper addresses the informational asymmetry for constructing an ultrametric evolutionary tree from upper and lower bounds on pairwise distances between n given species. We show that the...

Modeling Gene Expression With Differential Equations (1999)

Ting Chen, Hongyu L. He, George M. Church

this paper, we propose a linear differential equation model for gene expression and two algorithms to solve the differential equations. Potentially, our methods answer the practical questions in (1)...

Fabrication of Micro-Optics for Diode Lasers and Amplifiers Using Ink-Jet Technology (1998)

Cox, W. R., Chen, Ting, Hoenigman, Rick

A new technology has been developed for fabrication of refractive microlenses using an ink- jet printing method. It offers the advantages of low-cost (no photo lithography, minimal optical material...

Collaborative support for asynchronous software development activites / (1998)

Chen, Ting.

Thesis (M.S) -- Brigham Young University. Dept. of Computer Science, 1998.

Pombe: A gene-finding and exon-intron structure prediction system for fission yeast. Yeast (1998)

Ting Chen, Q. Zhang

A special program developed by the authors, called Pombe, identifies protein coding regions in the Schizosaccharomyces pombe genome. Linear discriminant analysis was applied to predict 5�-terminal,...

Fabrication of Micro-Optics for Diode Lasers and Amplifiers Using Ink-Jet Technology. (1997)

Cox, W. R., Hayes, Don J., Chen, Ting, Ussery, Daryl, MacFarlane, Duncan

Microjet printing methods were explored for in situ fabrication of micro-optical elements for use with diode laser and amplifier systems. Fabrication capabilities were demonstrated for hemispherical,...

Computational genome analysis / (1997)

Chen, Ting.

Thesis (Ph. D.)--State University of New York at Stony Brook, 1997.

Trie-based data structures for sequence assembly (1997)

Ting Chen, Steven S. Skiena

Trie-based data structures for strings have proven themselves in a wide variety of text-searching and biological applications. Several distinct string data structures have been developed, including...

How Good is Genome-Level Fragment Assembly? (Extended Abstract) (1997)

Ting Chen, Steven S. Skiena

) Ting Chen Steven S. Skiena y Department of Computer Science State University of New York Stony Brook, NY 11794-4400 ftichenjskienag@cs.sunysb.edu October 17, 1997 1 Introduction In late Summer...

Time-Scale Modification Of Audio Signals With Combined Harmonic And Wavelet Representations (1997)

Khaled N. Hamdy, Ahmed H. Tewfik, Ting Chen, Satoshi Takagi

We propose a new time-scale modification method for high quality audio signals. Our approach strives to preserve pitch and timbre. In our method, the signal is represented as the sum of sinusoidal...

Trie-Based Data Structures for Sequence Assembly (1997)

Ting Chen, Steven S. Skiena

We investigate the application of trie-based data structures, suffix trees and suffix arrays in the problem of overlap detection in fragment assembly. Both data structures are theoretically and...

These patents were applied for when working in Oracle Corporation. (1996)

Advisor Prof, Jeffrey F. Naughton, Jiansheng Huang, Ting Chen, Anhai Doan, ...

emphases on techniques for interpreting the correctness and completeness of imprecise query results and on generalpurpose user-driven information extraction and integration systems for answering...

These patents were applied for when working in Oracle Corporation. (1996)

Advisor Prof, Jeffrey F. Naughton, Jiansheng Huang, Ting Chen, Anhai Doan, ...

emphases on techniques for interpreting the correctness and completeness of imprecise query results and on generalpurpose user-driven information extraction and integration systems for answering...

Sorting with Fixed-Length Reversals (1996)

Ting Chen, Steven S. Skiena

this paper, we study the problem of sorting permutations and circular permutations using as few fixed-length reversals as possible. Our problem is implicit in the popular TOP-SPIN

Sorting with Fixed-Length Reversals (1996)

Ting Chen, Steven S. Skiena

this paper, we study the problem of sorting permutations and circular permutations using as few fixed-length reversals as possible. Our problem is implicit in the popular TOP-SPIN

Artificial neural networks for 3-D motion analysis / (1995)

Chen, Ting.

Photocopy of the microreproduction of original.

Sorting with Fixed-Length Reversals (1995)

Ting Chen, Steve Skiena

this paper, we study the problem of sorting permutations and circular permutations using as few fixed-length reversals as possible. Our problem is implicit in the popular TOP-SPIN

A dynamic programming algorithm for haplotype block partitioning

Zhang, Kui, Deng, Minghua, Chen, Ting, Waterman, Michael S., Sun, Fengzhu

We develop a dynamic programming algorithm for haplotype block partitioning to minimize the number of representative single nucleotide polymorphisms (SNPs) required to account for most of the common...

Inferring Domain–Domain Interactions From Protein–Protein Interactions

Deng, Minghua, Mehta, Shipra, Sun, Fengzhu, Chen, Ting

The interaction between proteins is one of the most important features of protein functions. Behind protein–protein interactions there are protein domains interacting physically with one another to...

Nucleocytoplasmic Shuttling of JAZ, a New Cargo Protein for Exportin-5

Chen, Ting, Brownawell, Amy M., Macara, Ian G.

Exportin-5 is a nuclear export receptor for certain classes of double-stranded RNA (dsRNA), including pre-micro-RNAs, viral hairpin RNAs, and some tRNAs. It can also export the RNA binding proteins...

Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies

Zhang, Kui, Qin, Zhaohui S., Liu, Jun S., Chen, Ting, Waterman, Michael S., Sun, Fengzhu

Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs)...

Network motif identification in stochastic networks

Jiang, Rui, Tu, Zhidong, Chen, Ting, Sun, Fengzhu

Network motifs have been identified in a wide range of networks across many scientific disciplines and are suggested to be the basic building blocks of most complex networks. Nonetheless, many...

A dynamic programming algorithm for haplotype block partitioning

Zhang, Kui, Deng, Minghua, Chen, Ting, Waterman, Michael S., Sun, Fengzhu

We develop a dynamic programming algorithm for haplotype block partitioning to minimize the number of representative single nucleotide polymorphisms (SNPs) required to account for most of the common...

Inferring Domain–Domain Interactions From Protein–Protein Interactions

Deng, Minghua, Mehta, Shipra, Sun, Fengzhu, Chen, Ting

The interaction between proteins is one of the most important features of protein functions. Behind protein–protein interactions there are protein domains interacting physically with one another to...

Nucleocytoplasmic Shuttling of JAZ, a New Cargo Protein for Exportin-5

Chen, Ting, Brownawell, Amy M., Macara, Ian G.

Exportin-5 is a nuclear export receptor for certain classes of double-stranded RNA (dsRNA), including pre-micro-RNAs, viral hairpin RNAs, and some tRNAs. It can also export the RNA binding proteins...

Haplotype Block Partitioning and Tag SNP Selection Using Genotype Data and Their Applications to Association Studies

Zhang, Kui, Qin, Zhaohui S., Liu, Jun S., Chen, Ting, Waterman, Michael S., Sun, Fengzhu

Recent studies have revealed that linkage disequilibrium (LD) patterns vary across the human genome with some regions of high LD interspersed by regions of low LD. A small fraction of SNPs (tag SNPs)...

Haplotype Block Partition with Limited Resources and Applications to Human Chromosome 21 Haplotype Data

Zhang, Kui, Sun, Fengzhu, Waterman, Michael S., Chen, Ting

Recent studies have shown that the human genome has a haplotype block structure such that it can be decomposed into large blocks with high linkage disequilibrium (LD) and relatively limited haplotype...

A precise packing sequence for self-assembled convex structures

Chen, Ting, Zhang, Zhenli, Glotzer, Sharon C.

Molecular simulations of the self-assembly of cone-shaped particles with specific, attractive interactions are performed. Upon cooling from random initial conditions, we find that the cones...

Efficient Genetic Method for Establishing Drosophila Cell Lines Unlocks the Potential to Create Lines of Specific Genotypes

Simcox, Amanda, Mitra, Sayan, Truesdell, Sharon, Paul, Litty, Chen, Ting, Butchar, Jonathan P., ...

Analysis of cells in culture has made substantial contributions to biological research. The versatility and scale of in vitro manipulation and new applications such as high-throughput gene silencing...

HLA-A2-Restricted Cytotoxic T Lymphocyte Epitopes from Human Heparanase as Novel Targets for Broad-Spectrum Tumor Immunotherapy1

Chen, Ting, Tang, Xu-Dong, Wan, Yin, Chen, Ling, Yu, Song-Tao, Xiong, Zhen, ...

Peptide vaccination for cancer immunotherapy requires identification of peptide epitopes derived from antigenic proteins associated with tumors. Heparanase (Hpa) is broadly expressed in various...

Jaceosidin Induces Apoptosis in Human Ovary Cancer Cells through Mitochondrial Pathway

Lv, Wen, Sheng, Xia, Chen, Ting, Xu, Qiang, Xie, Xing

We examined the antiproliferation effect of Jaceosidin (4′, 5, 7-trihydroxy-3′, 6-dimethoxyflavone) isolated from the herb of Artemisia vestita Wall on several human cancer cell lines. Jaceosidin...

Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy

Wang, Li, Sun, Fengzhu, Chen, Ting

A strategy is presented to prioritize the functional modules that mediate genetic perturbations and their phenotypic effects among candidate modules.

Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation

Ding, Yu, Xi, Ying, Chen, Ting, Wang, Ji-yong, Tao, Dong-lei, Wu, Zhi-Li, ...

The low-density lipoprotein receptor–related proteins 5 and 6 (LRP5/6) are coreceptors for Frizzled and transmit signals from the plasma membrane to the cytosol. However, the mechanism for LRP5/6...

Structural selection of graphene supramolecular assembly oriented by molecular conformation and alkyl chain

Chen, Qing, Chen, Ting, Pan, Ge-Bo, Yan, Hui-Juan, Song, Wei-Guo, Wan, Li-Jun, ...

Graphene molecules, hexafluorotribenzo[a,g,m]coronene with n-carbon alkyl chains (FTBC-Cn, n = 4, 6, 8, 12) and Janus-type “double-concave” conformation, are used to fabricate self-assembly on...

PerM: efficient mapping of short sequencing reads with periodic full sensitive spaced seeds

Chen, Yangho, Souaiaia, Tade, Chen, Ting

Motivation: The explosion of next-generation sequencing data has spawned the design of new algorithms and software tools to provide efficient mapping for different read lengths and sequencing...