Underwhelming the Immune Response: Effect of Slow Virus Growth on CD8+-T-Lymphocyte Responses
Bocharov, Gennady, Ludewig, Burkhard, Bertoletti, Antonio, Klenerman, Paul, Junt, Tobias, Krebs, Philippe, ...
The speed of virus replication has typically been seen as an advantage for a virus in overcoming the ability of the immune system to control its population growth. Under some circumstances, the...
Underwhelming the Immune Response: Effect of Slow Virus Growth on CD8+-T-Lymphocyte Responses
Bocharov, Gennady, Ludewig, Burkhard, Bertoletti, Antonio, Klenerman, Paul, Junt, Tobias, Krebs, Philippe, ...
Immunoprivileged status of the liver is controlled by Toll-like receptor 3 signaling
Lang, Karl S., Georgiev, Panco, Recher, Mike, Navarini, Alexander A., Bergthaler, Andreas, Heikenwalder, Mathias, ...
The liver is known to be a classical immunoprivileged site with a relatively high resistance against immune responses. Here we demonstrate that highly activated liver-specific effector CD8+ T cells...
Henning, Golo, Ohl, Lars, Junt, Tobias, Reiterer, Phillip, Brinkmann, Volker, Nakano, Hideki, ...
Cognate interaction of chemokine receptor CCR7 on lymphocytes with its ligands CCL19 and CCL21 expressed on high endothelial venules (HEVs) is essential for effective migration of T and B cells...
Overexpression of Lymphotoxin in T Cells Induces Fulminant Thymic Involution
Heikenwalder, Mathias, Prinz, Marco, Zeller, Nicolas, Lang, Karl S., Junt, Tobias, Rossi, Simona, ...
Activated lymphocytes and lymphoid-tissue inducer cells express lymphotoxins (LTs), which are essential for the organogenesis and maintenance of lymphoreticular microenvironments. Here we describe...