Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase
Manfredi, Mark G., Ecsedy, Jeffrey A., Meetze, Kristan A., Balani, Suresh K., Burenkova, Olga, Chen, Wei, ...
Increased Aurora A expression occurs in a variety of human cancers and induces chromosomal abnormalities during mitosis associated with tumor initiation and progression. MLN8054 is a selective...