Todd Wylie

Nematode.net update 2008: improvements enabling more efficient data mining and comparative nematode genomics (2009)

Martin, John, Abubucker, Sahar, Wylie, Todd, Yin, Yong, Wang, Zhengyuan, Mitreva, Makedonka

Nematode.net (http://nematode.net) is a publicly available resource dedicated to the study of parasitic nematodes. In 2000, the Genome Center at Washington University (GC) joined a consortium...

VarScan: variant detection in massively parallel sequencing of individual and pooled samples (2009)

Koboldt, Daniel C., Chen, Ken, Wylie, Todd, Larson, David E., McLellan, Michael D., Mardis, Elaine R., ...

Summary: Massively parallel sequencing technologies hold incredible promise for the study of DNA sequence variation, particularly the identification of variants affecting human disease. The...

NemaPath: online exploration of KEGG-based metabolic pathways for nematodes (2008)

Wylie, Todd, Martin, John, Abubucker, Sahar, Yin, Yong, Messina, David, Wang, Zhengyuan, ...

Abstract Background Nematode.net http://www.nematode.net is a web-accessible resource for investigating gene sequences from parasitic and free-living nematode genomes. Beyond the well-characterized...

Genome analysis of the platypus reveals unique signatures of evolution (2008)

Warren, Wesley C., Hillier, LaDeana W., Marshall Graves, Jennifer A., Birney, Ewan, Ponting, Chris P., Grützner, Frank, ...

We present a draft genome sequence of the platypus, Ornithorhynchus anatinus. This monotreme exhibits a fascinating combination of reptilian and mammalian characters. For example, platypuses have a...

Codon usage patterns in Nematoda: analysis based on over 25 million codons in thirty-two species (2006)

Mitreva, Makedonka, Wendl, Michael C, Martin, John, Wylie, Todd, Yin, Yong, Larson, Allan, ...

Abstract Background Codon usage has direct utility in molecular characterization of species and is also a marker for molecular evolution. To understand codon usage within the diverse phylum Nematoda,...

2006 Mitreva et Volume al. 7, Issue 8, Article R75 Open Access (2006)

Makedonka Mitreva, John Martin, Todd Wylie, Yong Yin, Allan Larson, John Parkinson, ...

Codon usage patterns in Nematoda: analysis based on over 25 million codons in thirty-two species

Investigating hookworm genomes by comparative analysis of two Ancylostomaspecies (2005)

Mitreva, Makedonka, McCarter, James P, Arasu, Prema, Hawdon, John, Martin, John, Dante, Mike, ...

Abstract Background Hookworms, infecting over one billion people, are the mostly closely related major human parasites to the model nematode Caenorhabditis elegans . Applying genomics techniques to...

Comparative Genomics of Gene Expression in the Parasitic and Free-Living Nematodes Strongyloides stercoralis and Caenorhabditis elegans (2004)

Mitreva, Makedonka, McCarter, James P., Martin, John, Dante, Mike, Wylie, Todd, Chiapelli, Brandi, ...

Although developmental timing of gene expression is used to infer potential gene function, studies have yet to correlate this information between species. We analyzed 10,921 ESTs in 3311 clusters...

Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes (2004)

Wylie, Todd, Martin, John C., Dante, Michael, Mitreva, Makedonka Dautova, Clifton, Sandra W., Chinwalla, Asif, ...

Nematode.net (www.nematode.net) is a web‐ accessible resource for investigating gene sequences from nematode genomes. The database is an outgrowth of the parasitic nematode EST project at...

Analysis and functional classification of transcripts from the nematode Meloidogyne incognita (2003)

McCarter, James P, Dautova Mitreva, Makedonka, Martin, John, Dante, Mike, Wylie, Todd, Rao, Uma, ...

Abstract Background Plant parasitic nematodes are major pathogens of most crops. Molecular characterization of these species as well as the development of new techniques for control can benefit from...

Gene Discovery in the Apicomplexa as Revealed by EST Sequencing and Assembly of a Comparative Gene Database (2003)

Li, Li, Brunk, Brian P., Kissinger, Jessica C., Pape, Deana, Tang, Keliang, Cole, Robert H., ...

Large-scale EST sequencing projects for several important parasites within the phylum Apicomplexa were undertaken for the purpose of gene discovery. Included were several parasites of medical...

Analysis and functional classification of transcripts from the nematode Meloidogyne incognita

McCarter, James P, Dautova Mitreva, Makedonka, Martin, John, Dante, Mike, Wylie, Todd, Rao, Uma, ...

As an entrée to characterizing plant parasitic nematode genomes, 5,700 expressed sequence tags (ESTs) from the infective second-stage larvae (L2) of the root-knot nematode Meloidogyne incognita have...

Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes

Wylie, Todd, Martin, John C., Dante, Michael, Mitreva, Makedonka Dautova, Clifton, Sandra W., Chinwalla, Asif, ...

Nematode.net (www.nematode.net) is a web- accessible resource for investigating gene sequences from nematode genomes. The database is an outgrowth of the parasitic nematode EST project at Washington...

Comparative Genomics of Gene Expression in the Parasitic and Free-Living Nematodes Strongyloides stercoralis and Caenorhabditis elegans

Mitreva, Makedonka, McCarter, James P., Martin, John, Dante, Mike, Wylie, Todd, Chiapelli, Brandi, ...

Although developmental timing of gene expression is used to infer potential gene function, studies have yet to correlate this information between species. We analyzed 10,921 ESTs in 3311 clusters...

Gene Discovery in the Apicomplexa as Revealed by EST Sequencing and Assembly of a Comparative Gene Database

Li, Li, Brunk, Brian P., Kissinger, Jessica C., Pape, Deana, Tang, Keliang, Cole, Robert H., ...

Large-scale EST sequencing projects for several important parasites within the phylum Apicomplexa were undertaken for the purpose of gene discovery. Included were several parasites of medical...

Analysis and functional classification of transcripts from the nematode Meloidogyne incognita

McCarter, James P, Dautova Mitreva, Makedonka, Martin, John, Dante, Mike, Wylie, Todd, Rao, Uma, ...

As an entrée to characterizing plant parasitic nematode genomes, 5,700 expressed sequence tags (ESTs) from the infective second-stage larvae (L2) of the root-knot nematode Meloidogyne incognita have...

Nematode.net: a tool for navigating sequences from parasitic and free-living nematodes

Wylie, Todd, Martin, John C., Dante, Michael, Mitreva, Makedonka Dautova, Clifton, Sandra W., Chinwalla, Asif, ...

Nematode.net (www.nematode.net) is a web- accessible resource for investigating gene sequences from nematode genomes. The database is an outgrowth of the parasitic nematode EST project at Washington...

Comparative Genomics of Gene Expression in the Parasitic and Free-Living Nematodes Strongyloides stercoralis and Caenorhabditis elegans

Mitreva, Makedonka, McCarter, James P., Martin, John, Dante, Mike, Wylie, Todd, Chiapelli, Brandi, ...

Although developmental timing of gene expression is used to infer potential gene function, studies have yet to correlate this information between species. We analyzed 10,921 ESTs in 3311 clusters...

Gene Discovery in the Apicomplexa as Revealed by EST Sequencing and Assembly of a Comparative Gene Database

Li, Li, Brunk, Brian P., Kissinger, Jessica C., Pape, Deana, Tang, Keliang, Cole, Robert H., ...

Large-scale EST sequencing projects for several important parasites within the phylum Apicomplexa were undertaken for the purpose of gene discovery. Included were several parasites of medical...

Codon usage patterns in Nematoda: analysis based on over 25 million codons in thirty-two species

Mitreva, Makedonka, Wendl, Michael C, Martin, John, Wylie, Todd, Yin, Yong, Larson, Allan, ...

A codon usage table for 32 nematode species is presented and suggests that total genomic GC content drives codon usage.

Nematode.net update 2008: improvements enabling more efficient data mining and comparative nematode genomics

Martin, John, Abubucker, Sahar, Wylie, Todd, Yin, Yong, Wang, Zhengyuan, Mitreva, Makedonka

Nematode.net (http://nematode.net) is a publicly available resource dedicated to the study of parasitic nematodes. In 2000, the Genome Center at Washington University (GC) joined a consortium...