Tom J. Humphrey

Amoxicillin therapy of poultry flocks: effect upon the selection of amoxicillin-resistant commensal Campylobacter spp. (2009)

Elviss, Nicola C., Williams, Lisa K., Jørgensen, Frieda, Chisholm, Stephanie A., Lawson, Andrew J., Swift, Craig, ...

Background The aim of this study was to investigate the effect of amoxicillin therapy of poultry flocks upon the persistence of commensal Campylobacter spp. and the incidence of antibiotic...

Prolonged treatment of Salmonella enterica serovar Typhimurium with commercial disinfectants selects for multiple antibiotic resistance, increased efflux and reduced invasiveness (2007)

Karatzas, Kimon A. G., Webber, Mark A., Jorgensen, Frieda, Woodward, Martin J., Piddock, Laura J. V., Humphrey, Tom J.

Objectives To study how disinfectants affect antimicrobial susceptibility and phenotype of Salmonella enterica serovar Typhimurium SL1344. Methods Wild-type strain SL1344 and its isogenic gyrA...

Prevalence and Subtypes of Ciprofloxacin-Resistant Campylobacter spp. in Commercial Poultry Flocks before, during, and after Treatment with Fluoroquinolones

Humphrey, Tom J., Jørgensen, Frieda, Frost, Jennifer A., Wadda, Haddy, Domingue, Gil, Elviss, Nicola C., ...

Five commercial broiler chicken flocks were treated with either difloxacin or enrofloxacin for a clinically relevant infection, as instructed by a veterinarian. Campylobacters were isolated from...

Prevalence and Subtypes of Ciprofloxacin-Resistant Campylobacter spp. in Commercial Poultry Flocks before, during, and after Treatment with Fluoroquinolones

Humphrey, Tom J., Jørgensen, Frieda, Frost, Jennifer A., Wadda, Haddy, Domingue, Gil, Elviss, Nicola C., ...

Five commercial broiler chicken flocks were treated with either difloxacin or enrofloxacin for a clinically relevant infection, as instructed by a veterinarian. Campylobacters were isolated from...

Piezotolerant Small-Colony Variants with Increased Thermotolerance, Antibiotic Susceptibility, and Low Invasiveness in a Clonal Staphylococcus aureus Population▿

Karatzas, Kimon A. G., Zervos, Angelos, Tassou, Chrysoula C., Mallidis, Costas G., Humphrey, Tom J.

Following a pressure treatment of a clonal Staphylococcus aureus culture with 400 MPa for 30 min, piezotolerant variants were isolated. Among 21 randomly selected survivors, 9 were piezotolerant and...

Phenotypic and Proteomic Characterization of Multiply Antibiotic-Resistant Variants of Salmonella enterica Serovar Typhimurium Selected Following Exposure to Disinfectants▿ †

Karatzas, Kimon A. G., Randall, Luke P., Webber, Mark, Piddock, Laura J. V., Humphrey, Tom J., Woodward, Martin J., ...

In previous work, Salmonella enterica serovar Typhimurium strain SL1344 was exposed to sublethal concentrations of three widely used farm disinfectants in daily serial passages for 7 days in an...