Genes regulating CEH-22 and pharyngeal development in C. elegans / (2004)
Thesis (Ph. D. in Biological Sciences)--University of Illinois at Chicago, 2004.
Reschly, Erica J., Spaulding, Christina, Vilimas, Tomas, Graham, W. Vallen, Brumbaugh, Rachel L., Aifantis, Iannis, ...
Loss of E2A transcription factor activity or activation of the intracellular form of Notch1 (ICN) leads to the development of leukemia or lymphoma in humans or mice, respectively. Current models...
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
Thompson, Benjamin J., Buonamici, Silvia, Sulis, Maria Luisa, Palomero, Teresa, Vilimas, Tomas, Basso, Giuseppe, ...
Recent studies have shown that activating mutations of NOTCH1 are responsible for the majority of T cell acute lymphoblastic leukemia (T-ALL) cases. Most of these mutations truncate its C-terminal...