Tomonori Iwama

Conversion of the Aminocrotonate Intermediate Limits the Rate of {gamma}-Elimination Reaction Catalyzed by L-Cystathionine {gamma}-lyase of the Yeast Saccharomyces cerevisiae (2003)

Yamagata, Shuzo, Yasugahira, Tomoko, Okuda, Yuriko, Iwama, Tomonori

l-Cystathionine &ggr;-lyase [EC 4.4.1.1] of Saccharomyces cerevisiae was shown to bind cofactor pyridoxal 5′-phosphate, up to 2 molecules/subunit. The association constants of the enzyme...

Inhibition of Aspartate Chemotaxis of Escherichia coli by Site-Directed Sulfhydryl Modification of the Receptor (1993)

Gomi, Sumiko, Lee, Lan, Iwama, Tomonori, Imae, Yasuo

Thr-154 of the chemoreceptor Tar in Escherichia coli is important for aspartate sensing. Taking advantage of the fact that Tar has no Cys residues, we have further investigated the role of Thr-154 by...

Mutational Analysis of Ligand Recognition by Tcp, the Citrate Chemoreceptor of Salmonella enterica Serovar Typhimurium

Iwama, Tomonori, Nakao, Ko-Ichiro, Nakazato, Hiroshi, Yamagata, Shuzo, Homma, Michio, Kawagishi, Ikuro

The chemoreceptor Tcp mediates taxis to citrate. To identify citrate-binding residues, we substituted cysteine for seven basic or polar residues that are chosen based on the comparison of Tcp with...

Occurrence of Transsulfuration in Synthesis of l-Homocysteine in an Extremely Thermophilic Bacterium, Thermus thermophilus HB8

Yamagata, Shuzo, Ichioka, Kazuhito, Goto, Koji, Mizuno, Yasuko, Iwama, Tomonori

A cell extract of an extremely thermophilic bacterium, Thermus thermophilus HB8, cultured in a synthetic medium catalyzed cystathionine γ-synthesis with O-acetyl-l-homoserine and l-cysteine as...

Immobilization of Saccharomyces cerevisiae Cystathionine γ-Lyase and Application of the Product to Cystathionine Synthesis

Yamagata, Shuzo, Akamatsu, Tsuyoshi, Iwama, Tomonori

Cystathionine γ-lyase of Saccharomyces cerevisiae was immobilized to aminohexyl-Sepharose through the cofactor pyridoxal 5′-phosphate and was characterized with respect to its cystathionine...

Mutational Analysis of Ligand Recognition by Tcp, the Citrate Chemoreceptor of Salmonella enterica Serovar Typhimurium

Iwama, Tomonori, Nakao, Ko-Ichiro, Nakazato, Hiroshi, Yamagata, Shuzo, Homma, Michio, Kawagishi, Ikuro

The chemoreceptor Tcp mediates taxis to citrate. To identify citrate-binding residues, we substituted cysteine for seven basic or polar residues that are chosen based on the comparison of Tcp with...

Occurrence of Transsulfuration in Synthesis of l-Homocysteine in an Extremely Thermophilic Bacterium, Thermus thermophilus HB8

Yamagata, Shuzo, Ichioka, Kazuhito, Goto, Koji, Mizuno, Yasuko, Iwama, Tomonori

A cell extract of an extremely thermophilic bacterium, Thermus thermophilus HB8, cultured in a synthetic medium catalyzed cystathionine γ-synthesis with O-acetyl-l-homoserine and l-cysteine as...

Immobilization of Saccharomyces cerevisiae Cystathionine γ-Lyase and Application of the Product to Cystathionine Synthesis

Yamagata, Shuzo, Akamatsu, Tsuyoshi, Iwama, Tomonori

Cystathionine γ-lyase of Saccharomyces cerevisiae was immobilized to aminohexyl-Sepharose through the cofactor pyridoxal 5′-phosphate and was characterized with respect to its cystathionine...