Tong Hao

Resource A Protein–Protein Interaction Network for Human Inherited Ataxias and Disorders of Purkinje Cell Degeneration (2009)

Janghoo Lim, Tong Hao, Chad Shaw, Akash J. Patel, Gábor Szabó, Jean-françois Rual, ...

Many human inherited neurodegenerative disorders are characterized by loss of balance due to cerebellar Purkinje cell (PC) degeneration. Although the disease-causing mutations have been identified...

An empirical framework for binary interactome mapping (2009)

Venkatesan, Kavitha, Rual, Jean-Francois, Vazquez, Alexei, Stelzl, Ulrich, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...

Several attempts have been made to systematically map protein-protein interaction, or 'interactome', networks. However, it remains difficult to assess the quality and coverage of existing data sets....

Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network (2009)

Simonis, Nicolas, Rual, Jean-Francois, Carvunis, Anne-Ruxandra, Tasan, Murat, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...

Abstract: To provide accurate biological hypotheses and elucidate global properties of cellular networks, systematic identification of protein-protein interactions must meet high quality standards....

Investigation of Vertical Spiral Resonators for Low Frequency Metamaterial Design (2008)

Zhu, Jiwen, Hao, Tong, Stevens, Christopher J., Edwards, David J.

This paper thoroughly explores the characteristics of vertical spiral resonators (VSR). They exhibit rela-tively high Q factors and sizes around a few percent of the free space wavelength, which make...

A protein domain-based interactome network for C. elegans early embryogenesis (2008)

Boxem, Mike, Maliga, Zoltan, Klitgord, Niels, Li, Na, Lemmens, Irma, Mana, Miyeko, ...

Many protein-protein interactions are mediated through independently folding modular domains. Proteome-wide efforts to model protein-protein interaction or "interactome" networks have largely ignored...

Revisiting the Saccharomyces cerevisiae predicted ORFeome (2008)

Li, Qian-Ru, Carvunis, Anne-Ruxandra, Yu, Haiyuan, Han, Jing-Dong J., Zhong, Quan, Simonis, Nicolas, ...

Accurately defining the coding potential of an organism, i.e., all protein-encoding open reading frames (ORFs) or “ORFeome,” is a prerequisite to fully understand its biology. ORFeome annotation...

A first version of the Caenorhabditis elegans Promoterome (2004)

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Evidence for dynamically organized modularity in the yeast protein-protein interaction network (2004)

Han, Jing-Dong J., Bertin, Nicolas, Hao, Tong, Goldberg, Debra S., Berriz, Gabriel F., Zhang, Lan V., ...

In apparently scale-free protein-protein interaction networks, or 'interactome' networks, most proteins interact with few partners, whereas a small but significant proportion of proteins, the 'hubs',...

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions (2004)

Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...

The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...

Human ORFeome Version 1.1: A Platform for Reverse Proteomics (2004)

Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...

The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....

Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library (2004)

Rual, Jean-François, Ceron, Julian, Koreth, John, Hao, Tong, Nicot, Anne-Sophie, Hirozane-Kishikawa, Tomoko, ...

The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data...

A First Version of the Caenorhabditis elegans Promoterome (2004)

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Generation of the Brucella melitensis ORFeome Version 1.1 (2004)

Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...

The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...

Characterization of regulatory mechanisms of cell-cell interaction-dependent genes of Myxococcus xanthus /--by Tong Hao. (2001)

Hao, Tong.

Thesis (Ph. D.)--Michigan State University. Dept. of Biochemistry and Molecular Biology, 2001.

Identification of the Ω4514 Regulatory Region, a Developmental Promoter of Myxococcus xanthus That Is Transcribed In Vitro by the Major Vegetative RNA Polymerase

Hao, Tong, Biran, Dvora, Velicer, Gregory J., Kroos, Lee

Ω4514 is the site of a Tn5 lac insertion in the Myxococcus xanthus genome that fuses lacZ expression to a developmentally regulated promoter. DNA upstream of the insertion site was cloned, and the...

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions

Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...

The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...

Human ORFeome Version 1.1: A Platform for Reverse Proteomics

Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...

The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....

Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library

Rual, Jean-François, Ceron, Julian, Koreth, John, Hao, Tong, Nicot, Anne-Sophie, Hirozane-Kishikawa, Tomoko, ...

The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data...

A First Version of the Caenorhabditis elegans Promoterome

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Generation of the Brucella melitensis ORFeome Version 1.1

Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...

The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...

Identification of the Ω4514 Regulatory Region, a Developmental Promoter of Myxococcus xanthus That Is Transcribed In Vitro by the Major Vegetative RNA Polymerase

Hao, Tong, Biran, Dvora, Velicer, Gregory J., Kroos, Lee

Ω4514 is the site of a Tn5 lac insertion in the Myxococcus xanthus genome that fuses lacZ expression to a developmentally regulated promoter. DNA upstream of the insertion site was cloned, and the...

C. elegans ORFeome Version 3.1: Increasing the Coverage of ORFeome Resources With Improved Gene Predictions

Lamesch, Philippe, Milstein, Stuart, Hao, Tong, Rosenberg, Jennifer, Li, Ning, Sequerra, Reynaldo, ...

The first version of the Caenorhabditis elegans ORFeome cloning project, based on release WS9 of Wormbase (August 1999), provided experimental verifications for ∼55% of predicted protein-encoding...

Human ORFeome Version 1.1: A Platform for Reverse Proteomics

Rual, Jean-François, Hirozane-Kishikawa, Tomoko, Hao, Tong, Bertin, Nicolas, Li, Siming, Dricot, Amélie, ...

The advent of systems biology necessitates the cloning of nearly entire sets of protein-encoding open reading frames (ORFs), or ORFeomes, to allow functional studies of the corresponding proteomes....

Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based RNAi Library

Rual, Jean-François, Ceron, Julian, Koreth, John, Hao, Tong, Nicot, Anne-Sophie, Hirozane-Kishikawa, Tomoko, ...

The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data...

A First Version of the Caenorhabditis elegans Promoterome

Dupuy, Denis, Li, Qian-Ru, Deplancke, Bart, Boxem, Mike, Hao, Tong, Lamesch, Philippe, ...

An important aspect of the development of systems biology approaches in metazoans is the characterization of expression patterns of nearly all genes predicted from genome sequences. Such...

Generation of the Brucella melitensis ORFeome Version 1.1

Dricot, Amélie, Rual, Jean-François, Lamesch, Philippe, Bertin, Nicolas, Dupuy, Denis, Hao, Tong, ...

The bacteria of the Brucella genus are responsible for a worldwide zoonosis called brucellosis. They belong to the α-proteobacteria group, as many other bacteria that live in close association with...

Revisiting the Saccharomyces cerevisiae predicted ORFeome

Li, Qian-Ru, Carvunis, Anne-Ruxandra, Yu, Haiyuan, Han, Jing-Dong J., Zhong, Quan, Simonis, Nicolas, ...

Accurately defining the coding potential of an organism, i.e., all protein-encoding open reading frames (ORFs) or “ORFeome,” is a prerequisite to fully understand its biology. ORFeome annotation...