Tony Schountz

Genomic organization and phylogenetic utility of deer mouse (Peromyscus maniculatus) lymphotoxin-alpha and lymphotoxin-beta (2008)

Richens, Tiffany, Palmer, Aparna, Prescott, Joseph, Schountz, Tony

Abstract Background Deer mice ( Peromyscus maniculatus ) are among the most common mammals in North America and are important reservoirs of several human pathogens, including Sin Nombre hantavirus...

Profiling helper T cell subset gene expression in deer mice (2006)

Oko, Lauren, Aduddell-Swope, Bethany, Willis, Derall, Hamor, Robyn, Coons, Teresa A, Hjelle, Brian, ...

Abstract Background Deer mice ( Peromyscus maniculatus ) are the most common mammals in North America and are reservoirs for several zoonotic agents, including Sin Nombre virus (SNV), the principal...

Generation of competent bone marrow-derived antigen presenting cells from the deer mouse (Peromyscus maniculatus) (2004)

Davenport, Bennett J, Willis, Derall G, Prescott, Joseph, Farrell, Regina M, Coons, Teresa A, Schountz, Tony

Abstract Background Human infections with Sin Nombre virus (SNV) and related New World hantaviruses often lead to hantavirus cardiopulmonary syndrome (HCPS), a sometimes fatal illness. Lungs of...

Research Article: Isolation and cytokine gene expression of deer mouse peritoneal macrophages (2004)

Tiffany Richens, Joseph Prescott, Rebecca A. Staudenmaier, Tony Schountz

Deer mice (Peromyscus maniculatus) are the principal reservoir hosts of Sin Nombre hantavirus (SNV). Once infected, deer mice remain persistently infected for the remainder of their lives. It is...

Research Article: Genomic organization of deer mouse (Peromyscus maniculatus) tumor necrosis factor (2004)

Renata M. Green, Melissa M. Herbst, Tony Schountz

Tumor necrosis factor (TNF) is a mediator of inflammation during immune responses and is produced by activated macrophages and T cells. It is synthesized as a membrane-bound homotrimer that is...

Cloning and characterization of deer mouse (Peromyscus maniculatus) cytokine and chemokine cDNAs (2004)

Schountz, Tony, Green, Renata, Davenport, Bennett, Buniger, Amie, Richens, Tiffany, Root, J, ...

Abstract Background Sin Nombre virus (SNV) establishes a persistent infection in the deer mouse, Peromyscus maniculatus . A strong antibody response occurs in response to SNV infection, but the role...

Bats: Important Reservoir Hosts of Emerging Viruses

Calisher, Charles H., Childs, James E., Field, Hume E., Holmes, Kathryn V., Schountz, Tony

Bats (order Chiroptera, suborders Megachiroptera [“flying foxes”] and Microchiroptera) are abundant, diverse, and geographically widespread. These mammals provide us with resources, but their...

Regulatory T cell-like responses in deer mice persistently infected with Sin Nombre virus

Schountz, Tony, Prescott, Joseph, Cogswell, Ann C., Oko, Lauren, Mirowsky-Garcia, Katy, Galvez, Alejandra P., ...

Hantavirus cardiopulmonary syndrome is a zoonotic illness associated with a systemic inflammatory immune response, capillary leak, noncardiogenic pulmonary edema, and shock in humans. Cytokines,...