Torsten Christ

Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK,ACh channels in patients with chronic atrial fibrillation (2007)

Voigt, Niels, Friedrich, Adina, Bock, Manja, Wettwer, Erich, Christ, Torsten, Knaut, Michael, ...

Objective: In chronic atrial fibrillation (cAF) the potassium current IK,ACh develops agonist-independent constitutive activity. We hypothesized that abnormal phosphorylation-dependent regulation...

Carvedilol blocks beta(2)- more than beta(1)-adrenoceptors in human heart (2006)

Molenaar, Peter, Christ, Torsten, Ravens, Ursula, Kaumann, Alberto

Objective: To understand the basis of the effectiveness of carvedilol in heart failure by determining its specific properties at human heart and beta(2)-adrenoceptors. Methods: The positive inotropic...

Carvedilol blocks beta(2)- more than beta(1)-adrenoceptors in human heart (2006)

Molenaar, Peter, Christ, Torsten, Ravens, Ursula, Kaumann, Alberto

Objective: To understand the basis of the effectiveness of carvedilol in heart failure by determining its specific properties at human heart and beta(2)-adrenoceptors. Methods: The positive inotropic...

Carvedilol blocks {beta}2- more than {beta}1-adrenoceptors in human heart (2006)

Molenaar, Peter, Christ, Torsten, Ravens, Ursula, Kaumann, Alberto

Objective: To understand the basis of the effectiveness of carvedilol in heart failure by determining its specific properties at human heart β1- and β2-adrenoceptors. Methods: The positive...

Electrophysiological properties of human mesenchymal stem cells

Heubach, Jürgen F, Graf, Eva M, Leutheuser, Judith, Bock, Manja, Balana, Bartosz, Zahanich, Ihor, ...

Human mesenchymal stem cells (hMSC) have gained considerable interest due to their potential use for cell replacement therapy and tissue engineering. One strategy is to differentiate these bone...

Electrophysiological properties of human mesenchymal stem cells

Heubach, Jürgen F, Graf, Eva M, Leutheuser, Judith, Bock, Manja, Balana, Bartosz, Zahanich, Ihor, ...

Human mesenchymal stem cells (hMSC) have gained considerable interest due to their potential use for cell replacement therapy and tissue engineering. One strategy is to differentiate these bone...

Pharmacodynamics of propiverine and three of its main metabolites on detrusor contraction

Wuest, Melinda, Hecht, Juliane, Christ, Torsten, Braeter, Manfred, Schoeberl, Christian, Hakenberg, Oliver W, ...

Besides its antimuscarinic effects, propiverine may possess an additional mode of action. We compared the effects of propiverine, three of its metabolites (M-5, M-6, M-14) and atropine in human, pig...