Scientific Commons: Torsten Wüstefeld

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury (2005)

Assmus, Ulrike, Wüstefeld, Torsten, Meyer Zu Vilsendorf, Andreas, Schmidt-Supprian, Mark, ...

The inhibitor of NF-kappaB (I-kappaB) kinase (IKK) complex consists of 3 subunits, IKK1, IKK2, and NF-kappaB essential modulator (NEMO), and is involved in the activation of NF-kappaB by various...

The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury (2005)

Wüstefeld, Torsten, Assmus, Ulrike, Rose-John, Stefan, Müller, Michael, ...

Increasing evidence demonstrates that IL-6 has a protective role during liver injury. IL-6 activates intracellular pathways via the gp130 receptor. In order to identify IL-6-gp130 pathways involved...

Met provides essential signals for liver regeneration

Borowiak, Malgorzata, Garratt, Alistair N., Wüstefeld, Torsten, Strehle, Michael, Trautwein, Christian, Birchmeier, Carmen

Genetic analysis in mice has demonstrated a crucial role of the Met tyrosine kinase receptor and its ligand, hepatocyte growth factor/scatter factor (HGF/SF), in development of the liver, muscle, and...

The IL-6–gp130–STAT3 pathway in hepatocytes triggers liver protection in T cell–mediated liver injury

Klein, Christian, Wüstefeld, Torsten, Assmus, Ulrike, Roskams, Tania, Rose-John, Stefan, Müller, Michael, ...

Increasing evidence demonstrates that IL-6 has a protective role during liver injury. IL-6 activates intracellular pathways via the gp130 receptor. In order to identify IL-6–gp130 pathways involved...

Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury

Luedde, Tom, Assmus, Ulrike, Wüstefeld, Torsten, Meyer Zu Vilsendorf, Andreas, Roskams, Tania, Schmidt-Supprian, Mark, ...

The inhibitor of NF-κB (I-κB) kinase (IKK) complex consists of 3 subunits, IKK1, IKK2, and NF-κB essential modulator (NEMO), and is involved in the activation of NF-κB by various stimuli. IKK2 or...