Toshiro Niki

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices (2008)

Nobumoto, Atsuya, Nagahara, Keiko, Oomizu, Souichi, Katoh, Shigeki, Nishi, Nozomu, Takeshita, Keisuke, ...

We previously described an inverse correlation between galectin-9 (Gal-9) expression and metastasis in patients with malignant melanoma and breast cancer. This study verified the ability of Gal-9 to...

Sclerosing Hemangioma of the Lung with Cystic Appearance (2003)

Kitagawa, Hiroshi, Goto, Akiteru, Minami, Manabu, Nakajima, Jun, Niki, Toshiro, Fukayama, Masashi

A case of cystic sclerosing hemangioma of the lung is reported. A chest X-ray of a 55-year-old woman who had been suffering from a cough with sputum for several months revealed an abnormal nodular...

Sclerosing Hemangioma of the Lung with Cystic Appearance (2003)

Kitagawa, Hiroshi, Goto, Akiteru, Minami, Manabu, Nakajima, Jun, Niki, Toshiro, Fukayama, Masashi

Primary Synovial Sarcoma of the Lung: a Case Report Confirmed by Molecular Detection of SYT-SSX Fusion Gene Transcripts (2001)

Terasaki, Hiroshi, Niki, Toshiro, Hasegawa, Tadashi, Yamada, Tesshi, Suzuki, Kenji, Kusumoto, Masahiko, ...

We report a rare case of primary synovial sarcoma of the lung. The patient was a 49-year-old woman who presented with a well-defined oval-shaped mass in the left upper lobe on a chest radiograph. A...

Lung Carcinoma with Polypoid Growth in the Main Pulmonary Artery: Report of Two Cases (2000)

Yamaguchi, Takashi, Suzuki, Kenji, Asamura, Hisao, Kondo, Haruhiko, Niki, Toshiro, Yamada, Tesshi, ...

Invasion into the lumen of the main pulmonary artery is an uncommon mode of extension in lung carcinoma and its prognostic significance remains unclear. We describe here two resected cases of lung...

MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer

Nishioka, Michiho, Kohno, Takashi, Tani, Masachika, Yanaihara, Nozomu, Tomizawa, Yoshio, Otsuka, Ayaka, ...

Loss of heterozygosity on chromosome 22q has been detected in approximately 60% of advanced nonsmall cell lung carcinoma (NSCLC) as well as small cell lung carcinoma (SCLC), suggesting the presence...

MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer

Nishioka, Michiho, Kohno, Takashi, Tani, Masachika, Yanaihara, Nozomu, Tomizawa, Yoshio, Otsuka, Ayaka, ...

Loss of heterozygosity on chromosome 22q has been detected in approximately 60% of advanced nonsmall cell lung carcinoma (NSCLC) as well as small cell lung carcinoma (SCLC), suggesting the presence...

Frequent Co-Localization of Cox-2 and Laminin-5 γ2 Chain at the Invasive Front of Early-Stage Lung Adenocarcinomas

Niki, Toshiro, Kohno, Takashi, Iba, Sanae, Moriya, Yasumitsu, Takahashi, Yoko, Saito, Miyuki, ...

Laminin-5 is an extracellular matrix protein that plays a key role in cell migration and tumor invasion. Cox-2 is an induced isoform of cyclooxygenases that plays an important role in carcinogenesis,...

c-MET Expression in Myofibroblasts : Role in Autocrine Activation and Prognostic Significance in Lung Adenocarcinoma

Tokunou, Masahide, Niki, Toshiro, Eguchi, Keisuke, Iba, Sanae, Tsuda, Hitoshi, Yamada, Tesshi, ...

Hepatocyte growth factor (HGF) plays important roles in tumor development and progression. It is currently thought that the main action of HGF is of a paracrine nature: HGF produced by mesenchymal...

A selective novel low-molecular-weight inhibitor of IκB kinase-β (IKK-β) prevents pulmonary inflammation and shows broad anti-inflammatory activity

Ziegelbauer, Karl, Gantner, Florian, Lukacs, Nicholas W, Berlin, Aaron, Fuchikami, Kinji, Niki, Toshiro, ...

Pulmonary inflammatory diseases such as asthma are characterized by chronic, cell-mediated inflammation of the bronchial mucosa.Recruitment and activation of inflammatory cells is orchestrated by a...