Toshiyuki Takagi

Novel and potent inhibitors of stearoyl-CoA desaturase-1. Part II: Identification of 4-ethylamino-3-(2-hydroxyethoxy)-N-[5-(3-trifluoromethylbenzyl)thiazol-2-yl]benzamide and its biological evaluation (2009)

Uto, Yoshikazu, Ogata, Tsuneaki, Kiyotsuka, Yohei, Miyazawa, Yuriko, Ueno, Yuko, Kurata, Hitoshi, ...

The continuing investigation of SAR studies of 3-(2-hydroxyethoxy)-N-(5-benzylthiazol-2-yl)-benzamides as stearoyl-CoA desaturase-1 (SCD-1) inhibitors is reported. Our prior hit-to-lead effort...

Photoresponsive polymer gel microvalves controlled by local light irradiation (2007)

Sugiura, Shinji, Sumaru, Kimio, Ohi, Katsuhide, Hiroki, Kazuaki, Takagi, Toshiyuki, Kanamori, Toshiyuki

This paper presents independent control of multiple microvalves, which are opened by local light irradiation. The application of photoresponsive polymer gel, which was developed by our research...

Evolution and Progression in Malignant Lymphoma of Waldeyer's Ring: Histopathological and Immunohistochemical Studies of Three Cases of Total Tonsillectomy (1990)

Takagi, Toshiyuki, Mikata, Atsuo

Histopathological and immunohistochemical studies were performed in three patients with malignant lymphoma of Waldeyer's ring (ML-WR) who underwent total tonsillectomies. Residual reactive follicles...

Intermediate-dose Cytosine Arabinoside in the Treatment of Recurrent or Refractory Non-Hodgkin's Lymphoma (1989)

Takagi, Toshiyuki, Sakai, Chikara, Oguro, Masao

Twelve patients with recurrent or refractory non-Hodgkin's lymphoma (NHL) were treated with an intermediate-dose of cytosine arabinoside (CA) by continuous i.v. infusion in combination with...

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

Wada, Tadashi, Takagi, Toshiyuki, Yamaguchi, Yuki, Ferdous, Anwarul, Imai, Takeshi, Hirose, Susumu, ...

We report the identification of a transcription elongation factor from HeLa cell nuclear extracts that causes pausing of RNA polymerase II (Pol II) in conjunction with the transcription inhibitor...

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

Wada, Tadashi, Takagi, Toshiyuki, Yamaguchi, Yuki, Ferdous, Anwarul, Imai, Takeshi, Hirose, Susumu, ...

We report the identification of a transcription elongation factor from HeLa cell nuclear extracts that causes pausing of RNA polymerase II (Pol II) in conjunction with the transcription inhibitor...

ホジキン病の治療成績 : 千葉悪性リンパ腫検討会の共同研究の結果

高木, 敏之, タカギ, トシユキ, Takagi, Toshiyuki, TAKAGI, Toshiyuki, 三方, 淳男, ミカタ, アツオ, ...

千葉悪性リンパ腫検討会に登録された未治療ホジキン病22例に対して治療研究を行った。治療法の骨子は(1)若年者の病期I-IIで巨大縦隔腫瘤のない症...

ホジキン病の治療成績 : 千葉悪性リンパ腫検討会の共同研究の結果

高木, 敏之, タカギ, トシユキ, Takagi, Toshiyuki, TAKAGI, Toshiyuki, 三方, 淳男, ミカタ, アツオ, ...

千葉悪性リンパ腫検討会に登録された未治療ホジキン病22例に対して治療研究を行った。治療法の骨子は(1)若年者の病期I-IIで巨大縦隔腫瘤のない症...

The Possibility of Muscle Tissue Reconstruction Using Shape Memory Alloys

Luo, Yun, Higa, Masaru, Amae, Shintaro, Yambe, Tomoyuki, Okuyama, Takeshi, Takagi, Toshiyuki, ...

Severe dysfunction of muscle tissues can be treated by transplantation but the success rate is still not high enough. One possibility instead is to replace the dysfunctional muscle with artificial...