Toshiyuki Takahashi

Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling (2009)

Kohno, Takashi, Anzai, Toshihisa, Naito, Kotaro, Miyasho, Taku, Okamoto, Minoru, Yokota, Hiroshi, ...

Aims High-mobility group box 1 protein (HMGB1) is one of the recently defined damage-associated molecular pattern molecules derived from necrotic cells and activated macrophages. We investigated...

RWCP PC Cluster Programming Environment-- Extended Abstract-- (2007)

Yutaka Ishikawa, Atsushi Hori, Hiroshi Tezuka, Shinji Sumimoto, Toshiyuki Takahashi, Hiroshi Harada

Wehave been developing the SCore cluster system software running on top of Linux. As shown in Figure 1, the SCore System software consists of a global

The Design and Evaluation of High Performance Communication using a Gigabit Ethernet (2007)

Toshiyuki Takahashi, Yutaka Ishikawa

A high performance communication facility, called the GigaE PM, has been designed and implemented for parallel applications on clusters of computers using a Gigabit Ethernet. The GigaE PM provides...

Real World Computing Partnership (2007)

Yutaka Ishikawa, Atsushi Hori, Hiroshi Tezuka, Shinji Sumimoto, Toshiyuki Takahashi, Hiroshi Harada

A parallel programming system, called MPC++, provides parallel primitives such as a remote function invocation, a global pointer, and a synchronization structure using the C++ template feature. The...

RWCP PC Cluster Programming Environment-- Extended Abstract-- (2007)

Yutaka Ishikawa, Atsushi Hori, Hiroshi Tezuka, Shinji Sumimoto, Toshiyuki Takahashi, Hiroshi Harada

We have been developing the SCore cluster system software running on top of Linux. As shown in Figure 1, the SCore System software consists of a global

Real World Computing Partnership (2007)

Toshiyuki Takahashi, Hiroshi Tezuka, Atsushi Hori, Hiroshi Harada, Yutaka Ishikawa, Peter H. Beckmanz

Abstract. An MPI library, called MPICH-PM/CLUMP, has been implemented on a cluster of SMPs. MPICH-PM/CLUMP realizes zero copy message passing between nodes while using one copy message passing within...

Real World Computing Partnership (2007)

Yutaka Ishikawa, Hiroshi Tezuka, Atsushi Hori, Shinji Sumimoto, Toshiyuki Takahashi, Hiroshi Harada

The RWC PC Cluster II, consisting of 128 Intel Pentium Pro microprocessors connected by a Myricom Myrinet giga-bit network, achieves the comparable speed of a super computer such as Cray T3E. Its...

Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre (2007)

Takahashi, Toshiyuki, Fujihara, Kazuo, Nakashima, Ichiro, Misu, Tatsuro, Miyazawa, Isabelle, Nakamura, Masashi, ...

NMO-IgG is a disease-specific autoantibody for neuromyelitis optica (NMO) and its target antigen is aquaporin-4 (AQP4) water channel. Recently, we established a sensitive anti-AQP4 antibody assay...

Modeling of intertidal flow and geomorphology using N+2-field model (2006)

Takahashi, Toshiyuki, Arai, Hiroshi, Mutsuda, Hidemi, Doi, Yasuaki

Paper presented at The Seventh International Conference on HydroScience and Engineering (ICHE) hosted by the College of Engineering at Drexel Univeristy on September 10-13, 2006 in Philadelphia,...

World Wide Web Crawler (2002)

Takahashi, Toshiyuki, Soonsang, Hong, Taura, Kenjiro, Yonezawa, Akinori

We describe our ongoing work on world wide web crawling, a scalable web crawler architecture that can use resources distributed world-wide. The architecture allows us to use loosely managed compute...

PM2: High performance communication middleware for heterogeneous network environments (2000)

Toshiyuki Takahashi, Shinji Sumimoto, Atsushi Hori

This paper introduces a high performance communication middle layer, called PM2, for heterogeneous network environments. PM2 currently supports Myrinet, Ethernet, and SMP. Binary code written in PM2...

Platelet-derived growth factor induces cellular growth in cultured chick ventricular myocytes (1999)

Shimizu, Tatsuya, Kinugawa, Koh-ichiro, Yao, Atsushi, Sugishita, Yasuyuki, Sugishita, Kazuro, Harada, Kazumasa, ...

Objectives: Platelet-derived growth factor (PDGF) stimulates growth in various types of cells, but little is known about its effect on cardiac myocytes. Therefore, we examined whether PDGF had a...

Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y (1998)

Senmaru, Naoto, Shichinohe, Toshiaki, Takeuchi, Motoya, Miyamoto, Masaki, Sazawa, Ataru, Ogiso, Yoshifumi, ...

Our previous studies demonstrated that introduction of a dominant negative H-ras mutant, N116Y, inhibits the growth of various types of cancer cells in vitro. In this study, we tested the efficacy of...

Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y (1998)

Senmaru, Naoto, Shichinohe, Toshiaki, Takeuchi, Motoya, Miyamoto, Masaki, Sazawa, Ataru, Ogiso, Yoshifumi, ...

Our previous studies demonstrated that introduction of a dominant negative H-ras mutant, N116Y, inhibits the growth of various types of cancer cells in vitro. In this study, we tested the efficacy of...

Suppression of Erk activation and in vivo growth in esophageal cancer cells by the dominant negative Ras mutant, N116Y (1998)

Senmaru, Naoto, Shichinohe, Toshiaki, Takeuchi, Motoya, Miyamoto, Masaki, Sazawa, Ataru, Ogiso, Yoshifumi, ...

Our previous studies demonstrated that introduction of a dominant negative H-ras mutant, N116Y, inhibits the growth of various types of cancer cells in vitro. In this study, we tested the efficacy of...

High Performance Communication using a Gigabit Ethernet (1998)

Shinji Sumimoto, Hiroshi Tezuka, Atsushi Hori, Hiroshi Harada, Toshiyuki Takahashi, Yutaka Ishikawa

A high performance communication facility, called the GigaE PM, has been designed and implemented for parallel applications on clusters of computers using a Gigabit Ethernet. The GigaE PM provides...

Ca2+-growth coupling in angiotensin II-induced hypertrophy in cultured rat cardiac cells (1995)

Kinugawa, Koh-ichiro, Takahashi, Toshiyuki, Kohmoto, Osami, Yao, Atsushi, Ikenouchi, Hiroshi, Serizawa, Takashi

Objectives: There remain some controversies about the effect of angiotensin II on intracellular Ca2+ concentration ([Ca2+]i) in cardiac myocytes. The aim of this study was to investigate different...

Differences in molecular biological, biological and growth characteristics between the immortal and malignant hamster pancreatic cells (1995)

Takahashi, Toshiyuki, Moyer, Mary P., Cano, Martin, Wang, Qiming J., Mountjoy, Charles P., Sanger, Warren, ...

We compared morphological, biological and molecular biological patterns of a newly established, spontaneously immortalized pancreatic ductal cell line, TAKA-1, with a hamster pancreatic ductal...

Cardiomyocytes can be generated from marrow stromal cells in vitro

Makino, Shinji, Fukuda, Keiichi, Miyoshi, Shunichirou, Konishi, Fusako, Kodama, Hiroaki, Pan, Jing, ...

We have isolated a cardiomyogenic cell line (CMG) from murine bone marrow stromal cells. Stromal cells were immortalized, treated with 5-azacytidine, and spontaneously beating cells were repeatedly...

Cardiomyocytes can be generated from marrow stromal cells in vitro

Makino, Shinji, Fukuda, Keiichi, Miyoshi, Shunichirou, Konishi, Fusako, Kodama, Hiroaki, Pan, Jing, ...

We have isolated a cardiomyogenic cell line (CMG) from murine bone marrow stromal cells. Stromal cells were immortalized, treated with 5-azacytidine, and spontaneously beating cells were repeatedly...

The Role of the Thymus in Development of Necrotizing Arteritis in Transgenic Rats Carrying the env-pX Gene of Human T-Cell Leukemia Virus Type-I

Fugo, Kazunori, Ishizu, Akihiro, Ikeda, Hitoshi, Hayase, Hiroko, Sugaya, Toshiaki, Higuchi, Masato, ...

Necrotizing arteritis mimicking polyarteritis nodosa occurred in transgenic rats carrying the env-pX gene of human T-cell leukemia virus type I. To investigate the pathogenesis of necrotizing...

Arrest of Cytoplasmic Streaming Induces Algal Proliferation in Green Paramecia

Takahashi, Toshiyuki, Shirai, Yohji, Kosaka, Toshikazu, Hosoya, Hiroshi

A green ciliate Paramecium bursaria, bearing several hundreds of endosymbiotic algae, demonstrates rotational microtubule-based cytoplasmic streaming, in which cytoplasmic granules and endosymbiotic...