Tracy Melvin

World-to-chip interconnects for efficient loading of genomic DNA into microfluidic channels (2009)

Humphreys, Tim, Andersson, Johan, Sodervall, Ulf, Melvin, Tracy

A novel sloped interconnect for the efficient delivery of long genomic DNA fragments into a microfluidic channel is designed, fabricated and tested. Out-of-plane slopes are fabricated in silicon...

Flexible acoustic particle manipulation device with integrated optical waveguide for enhanced microbead assays (2009)

Glynne-Jones, Peter, Boltryk, Rosemary J., Hill, Martyn, Zhang, Fan, Dong, Liqin, Wilkinson, James S., ...

Realisation of a device intended for the manipulation and detection of bead-tagged DNA and other bio-molecules is presented. Acoustic radiation forces are used to manipulate polystyrene micro-beads...

Fabrication of macroporous polysilicon by nanosphere lithography (2008)

Chau, Chien Fat, Melvin, Tracy

The fabrication of ordered macroporous silicon is obtained by exploiting the self-assembly properties of polymer nanospheres. Here, we demonstrate the method by using nanospheres of 200 nm and 500...

Fabrication of macroporous polysilicon by nanosphere lithography (2008)

Chau, Chien Fat, Melvin, Tracy

The fabrication of ordered macroporous silicon is obtained by exploiting the self-assembly properties of polymer nanospheres. Here, we demonstrate the method by using nanospheres of 200nm and 500nm....

An integrated multimodal acoustic particle manipulator and optical evanescent field waveguide (2008)

Glynne-Jones, Peter, Hill, Martyn, Townsend, Rosemary J., Harris, Nicholas R., Wilkinson, James S., Zhang, Fan, ...

A new acoustic-optical-microfluidic system is presented for the manipulation of bead-tagged DNA molecules. Acoustic radiation forces are used to manipulate microspheres into and away from the...

Optimisation of analyte transport in integrated microfluidic affinity sensors for the quantification of low levels of analyte (2008)

Friedrich, Daniel, Please, Colin, Melvin, Tracy

New designs for microfluidic channels to be integrated with small-scale affinity sensors for analytical applications are provided. Theoretical approaches demonstrate efficient and uniform mass...

Optimisation of analyte transport in integrated microfluidic affinity sensors for the quantification of low levels of analyte (2008)

Friedrich, Daniel, Please, Colin, Melvin, Tracy

New designs for microfluidic channels to be integrated with small-scale affinity sensors for analytical applications are provided. Theoretical approaches demonstrate efficient and uniform mass...

Editorial. Optical biosensing: future possibilities (2007)

Melvin, Tracy

"How the construction of oximeter sensors has evolved over the last decade is a reflection of the advancement in light sources and detectors from the optoelectronics and microelectronics research...

Nodal position in planar resonators for ultrasonic manipulation (2007)

Hill, Martyn, Glynne-Jones, Peter, Townsend, Rosemary J., Harris, Nicholas R., Cranny, Andrew W., Melvin, Tracy, ...

Ultrasonic manipulation of particles has significant potential, particularly in microfluidic devices for controlling and trapping biological cells. One approach to particle manipulation employs...

Quenching of CdSe quantum dot emission, a new approach for biosensing (2005)

Melvin, Tracy, Dyadyusha, Larysa, Yin, Huabing, Jaiswal, Supriya, Baumberg, Jeremy, Booy, Frank, ...

The emission of CdSe quantum dots linked to the 5-end of a DNA sequence is efficiently quenched by hybridisation with a complementary DNA strand with a gold nanoparticle attached at the 3-end;...

Quenching of CdSe quantum dot emission, a new approach for biosensing (2005)

Melvin, Tracy, Dyadyusha, Larysa, Yin, Huabing, Jaiswal, Supriya, Baumberg, Jeremy, Booy, Frank, ...

The emission of CdSe quantum dots linked to the 5-end of a DNA sequence is efficiently quenched by hybridisation with a complementary DNA strand with a gold nanoparticle attached at the 3-end;...

Quenching of CdSe quantum dot emission, a new approach for biosensing (2005)

Melvin, Tracy, Dyadyusha, Larysa, Yin, Huabing, Jaiswal, Supriya, Baumberg, Jeremy, Booy, Frank, ...

The emission of CdSe quantum dots linked to the 5-end of a DNA sequence is efficiently quenched by hybridisation with a complementary DNA strand with a gold nanoparticle attached at the 3-end;...

Design And Fabrication Of Passive Mixing Channels To Be Incorporated Into A Centrifugally Driven microfluidic System For Forensic Science Applications (2005)

Chau, Chien Fat, Melvin, Tracy

Recent advancement in microfluidic systems has been focusing on the development of micro total analysis systems and Lab-on-a-chip (LOC) systems for analytical and diagnostics in biochemical...

Design And Fabrication Of Passive Mixing Channels To Be Incorporated Into A Centrifugally Driven microfluidic System For Forensic Science Applications (2005)

Chau, Chien Fat, Melvin, Tracy

Recent advancement in microfluidic systems has been focusing on the development of micro total analysis systems and Lab-on-a-chip (LOC) systems for analytical and diagnostics in biochemical...

Design And Fabrication Of Passive Mixing Channels To Be Incorporated Into A Centrifugally Driven microfluidic System For Forensic Science Applications (2005)

Chau, Chien Fat, Melvin, Tracy

Recent advancement in microfluidic systems has been focusing on the development of micro total analysis systems and Lab-on-a-chip (LOC) systems for analytical and diagnostics in biochemical...

Photo-patterning of DNA oligonucleotides on silicon surfaces with micron-scale dimensions (2004)

Yin, Huabing B., Brown, Tom, Greef, Robert., Mailis, Sakellaris, Eason, Rob W., Wilkinson, James S., ...

A method is presented for the covalent attachment of oligonucleotides to silicon (100) surfaces patterned with micron-scale features. UV light exposure of hydrogen-terminated silicon (100) coated...

A new masking technology for deep glass etching and its microfluidic application (2004)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham J., Wilkinson, James S.

A new masking technology for wet etching of glass, to a depth of more than 300um, is reported. Various mask materials, which can be patterned by standard photolithography and metal etching processes,...

Investigation for the operation of an integrated peristaltic micropump (2004)

Husband, Ben, Bu, Minqiang, Evans, Alan G.R., Melvin, Tracy

An investigation into the pumping flow rates and the time-resolved membrane actuation of a microperistaltic pump integrated within a micro total analysis system (uTAS) is presented. The results...

A new masking technology for deep glass etching and its microfluidic application (2004)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham J., Wilkinson, James S.

A new masking technology for wet etching of glass, to a depth of more than 300um, is reported. Various mask materials, which can be patterned by standard photolithography and metal etching processes,...

Investigation for the operation of an integrated peristaltic micropump (2004)

Husband, Ben, Bu, Minqiang, Evans, Alan G.R., Melvin, Tracy

An investigation into the pumping flow rates and the time-resolved membrane actuation of a microperistaltic pump integrated within a micro total analysis system (uTAS) is presented. The results...

A new masking technology for deep glass etching and its microfluidic application (2004)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham J., Wilkinson, James S., Evans, Alan G.R.

A new masking technology for wet etching of glass, to a depth of more than 300 μm, is reported. Various mask materials, which can be patterned by standard photolithography and metal etching...

Photo-patterning of DNA oligonucleotides on silicon surfaces with micron-scale dimensions (2004)

Yin, Huabing B., Brown, Tom, Greef, Robert, Mailis, Sakellaris, Eason, Rob W., Wilkinson, James S., ...

A method is presented for the covalent attachment of oligonucleotides to silicon (100) surfaces patterned with micron-scale features. UV light exposure of hydrogen-terminated silicon (100) coated...

A new masking technology for deep glass etching and its microfluidic application (2004)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham J., Wilkinson, James S.

A new masking technology for wet etching of glass, to a depth of more than 300um, is reported. Various mask materials, which can be patterned by standard photolithography and metal etching processes,...

Investigation for the operation of an integrated peristaltic micropump (2004)

Husband, Ben, Bu, Minqiang, Evans, Alan G.R., Melvin, Tracy

An investigation into the pumping flow rates and the time-resolved membrane actuation of a microperistaltic pump integrated within a micro total analysis system (uTAS) is presented. The results...

Design and theoretical evaluation of a novel microfluidic device to be used for PCR (2003)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham, Wilkinson, James, Evans, Alan

The design of a novel, microfluidic chip with an integrated micro perisaltic pump and chambers for DNA amplification is described. This chip contains three reaction chambers stable at 90 degrees c,...

Design and theoretical evaluation of a novel microfluidic device to be used for PCR (2003)

Bu, Minqiang, Melvin, Tracy, Graham, Ensell, Wilkinson, James, Evans, Alan

The design of a novel, microfluidic chip with an integrated micro perisaltic pump and chambers for DNA amplification is described. This chip contains three reaction chambers stable at 90 degrees C,...

Design and theoretical evaluation of a novel microfluidic device to be used for PCR (2003)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham, Wilkinson, James, Evans, Alan

The design of a novel, microfluidic chip with an integrated micro perisaltic pump and chambers for DNA amplification is described. This chip contains three reaction chambers stable at 90 degrees c,...

Design and theoretical evaluation of a novel microfluidic device to be used for PCR (2003)

Bu, Minqiang, Melvin, Tracy, Graham, Ensell, Wilkinson, James, Evans, Alan

The design of a novel, microfluidic chip with an integrated micro perisaltic pump and chambers for DNA amplification is described. This chip contains three reaction chambers stable at 90 degrees C,...

Design and theoretical evaluation of a novel microfluidic device to be used for PCR (2003)

Bu, Minqiang, Melvin, Tracy, Ensell, Graham, Wilkinson, James, Evans, Alan

The design of a novel, microfluidic chip with an integrated micro perisaltic pump and chambers for DNA amplification is described. This chip contains three reaction chambers stable at 90 degrees c,...

Design and theoretical evaluation of a novel microfluidic device to be used for PCR (2003)

Bu, Minqiang, Melvin, Tracy, Graham, Ensell, Wilkinson, James, Evans, Alan

The design of a novel, microfluidic chip with an integrated micro perisaltic pump and chambers for DNA amplification is described. This chip contains three reaction chambers stable at 90 degrees C,...

Fluorescent Properties of Oligonucleotide-conjugated Thiazole Orange Probes¶ (2002)

Eric Privat, Tracy Melvin, Fabienne Mérola, Gerd Schweizer, Sylvie Prodhomme, Ulysse Asseline, ...

The fluorescence properties of thiazole orange, linked via a (1) hydrophobic alkyl or a (2) hydrophilic ethylene glycol chain to the central internucleotidic phosphate group of a...

Oligonucleotide-conjugated thiazole orange probes as “light-up” probes for messenger ribonucleic acid molecules in living cells (2001)

Privat, Eric, Melvin, Tracy, Asseline, Ulysse, Vigny, Paul

“Light-up” probes, icosa-α-thymidylate-thiazole orange conjugates, for the in situ time-resolved detection of messenger ribonucleic acid (mRNA) in living cells are evaluated. Upon annealing with...

Oligonucleotide-conjugated Thiazole Orange Probes as “Light-up” Probes for Messenger Ribonucleic Acid Molecules in Living Cells¶ (2001)

Eric Privat, Tracy Melvin, Ulysse Asseline, Paul Vigny

“Light-up” probes, icosa-α-thymidylate-thiazole orange conjugates, for the in situ time-resolved detection of messenger ribonucleic acid (mRNA) in living cells are evaluated. Upon annealing with...