The malaria secretome: from algorithms to essential function in blood stage infection. (2008)
Van Ooij, Christiaan, Tamez, Pamela, Bhattacharjee, Souvik, Hiller, N. Luisa, Harrison, Travis, Liolios, Konstantinos, ...
The malaria agent Plasmodium falciparum is predicted to export a "secretome" of several hundred proteins to remodel the host erythrocyte. Prediction of protein export is based on the presence of an...
Erythrocyte G Protein as a Novel Target for Malarial Chemotherapy (2006)
Sean C. Murphy, Travis Harrison, Heidi E. Hamm, Jon W. Lomasney, Narla Mohandas, Kasturi Haldar
BackgroundMalaria remains a serious health problem because resistance develops to all currently used drugs when their parasite targets mutate. Novel antimalarial drug targets are urgently needed to...
Lopez-Estraño, Carlos, Bhattacharjee, Souvik, Harrison, Travis, Haldar, Kasturi
When the malaria parasite Plasmodium falciparum infects an erythrocyte, it resides in a parasitophorous vacuole and remarkably exports proteins into the periphery of its host cell. Two of these...
Lauer, Sabine, VanWye, Jeffrey, Harrison, Travis, McManus, Heather, Samuel, Benjamin U., Hiller, N.Luisa, ...
Erythrocytes, which are incapable of endocytosis or phagocytosis, can be infected by the malaria parasite Plasmodium falciparum. We find that a transmembrane protein (Duffy),...
Lopez-Estraño, Carlos, Bhattacharjee, Souvik, Harrison, Travis, Haldar, Kasturi
When the malaria parasite Plasmodium falciparum infects an erythrocyte, it resides in a parasitophorous vacuole and remarkably exports proteins into the periphery of its host cell. Two of these...
Lauer, Sabine, VanWye, Jeffrey, Harrison, Travis, McManus, Heather, Samuel, Benjamin U., Hiller, N.Luisa, ...
Erythrocytes, which are incapable of endocytosis or phagocytosis, can be infected by the malaria parasite Plasmodium falciparum. We find that a transmembrane protein (Duffy),...
Erythrocyte G Protein as a Novel Target for Malarial Chemotherapy
Murphy, Sean C, Harrison, Travis, Hamm, Heidi E, Lomasney, Jon W, Mohandas, Narla, Haldar, Kasturi
Erythrocyte G protein signaling is needed for intracellular malarial parasite proliferation and thus may present a novel antimalarial target.
The Malaria Secretome: From Algorithms to Essential Function in Blood Stage Infection
Van Ooij, Christiaan, Tamez, Pamela, Bhattacharjee, Souvik, Hiller, N. Luisa, Harrison, Travis, Liolios, Konstantinos, ...
The malaria agent Plasmodium falciparum is predicted to export a “secretome” of several hundred proteins to remodel the host erythrocyte. Prediction of protein export is based on the presence of...