Turlough M. Finan

Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria (2006)

Yuan, Ze-Chun, Zaheer, Rahat, Morton, Richard, Finan, Turlough M.

In proteobacteria, genes whose expression is modulated in response to the external concentration of inorganic phosphate are often regulated by the PhoB protein which binds to a conserved motif (Pho...

The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti

Finan, Turlough M., Weidner, Stefan, Wong, Kim, Buhrmester, Jens, Chain, Patrick, Vorhölter, Frank J., ...

Analysis of the 1,683,333-nt sequence of the pSymB megaplasmid from the symbiotic N2-fixing bacterium Sinorhizobium meliloti revealed that the replicon has a high gene density with a total of 1,570...

Phosphate Assimilation in Rhizobium (Sinorhizobium) meliloti: Identification of a pit-Like Gene

Bardin, Sylvie D., Voegele, Ralf T., Finan, Turlough M.

Rhizobium meliloti mutants defective in the phoCDET-encoded phosphate transport system form root nodules on alfalfa plants that fail to fix nitrogen (Fix−). We have previously reported that two...

oriT-Directed Cloning of Defined Large Regions from Bacterial Genomes: Identification of the Sinorhizobium meliloti pExo Megaplasmid Replicator Region

Chain, Patrick S. G., Hernandez-Lucas, Ismael, Golding, Brian, Finan, Turlough M.

We have developed a procedure to directly clone large fragments from the genome of the soil bacterium Sinorhizobium meliloti. Specific regions to be cloned are first flanked by parallel copies of an...

Novel Pathway for Arsenic Detoxification in the Legume Symbiont Sinorhizobium meliloti

Yang, Hung-Chi, Cheng, Jiujun, Finan, Turlough M., Rosen, Barry P., Bhattacharjee, Hiranmoy

We report a novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti. Although a majority of ars operons consist of three genes, arsR (transcriptional regulator), arsB...

Novel DNA Sequences from Natural Strains of the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti†

Guo, Hong, Sun, Sheng, Finan, Turlough M., Xu, Jianping

Variation in genome size and content is common among bacterial strains. Identifying these naturally occurring differences can accelerate our understanding of bacterial attributes, such as ecological...

Regulation and Properties of PstSCAB, a High-Affinity, High-Velocity Phosphate Transport System of Sinorhizobium meliloti

Yuan, Ze-Chun, Zaheer, Rahat, Finan, Turlough M.

The properties and regulation of the pstSCAB-encoded Pi uptake system from the alfalfa symbiont Sinorhizobium meliloti are reported. We present evidence that the pstSCAB genes and the regulatory...

Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria

Yuan, Ze-Chun, Zaheer, Rahat, Morton, Richard, Finan, Turlough M.

In proteobacteria, genes whose expression is modulated in response to the external concentration of inorganic phosphate are often regulated by the PhoB protein which binds to a conserved motif (Pho...

Characterization of the β-Ketoadipate Pathway in Sinorhizobium meliloti

MacLean, Allyson M., MacPherson, Gordon, Aneja, Punita, Finan, Turlough M.

Aromatic compounds represent an important source of energy for soil-dwelling organisms. The β-ketoadipate pathway is a key metabolic pathway involved in the catabolism of the aromatic compounds...

The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti

Finan, Turlough M., Weidner, Stefan, Wong, Kim, Buhrmester, Jens, Chain, Patrick, Vorhölter, Frank J., ...

Analysis of the 1,683,333-nt sequence of the pSymB megaplasmid from the symbiotic N2-fixing bacterium Sinorhizobium meliloti revealed that the replicon has a high gene density with a total of 1,570...

Phosphate Assimilation in Rhizobium (Sinorhizobium) meliloti: Identification of a pit-Like Gene

Bardin, Sylvie D., Voegele, Ralf T., Finan, Turlough M.

Rhizobium meliloti mutants defective in the phoCDET-encoded phosphate transport system form root nodules on alfalfa plants that fail to fix nitrogen (Fix−). We have previously reported that two...

oriT-Directed Cloning of Defined Large Regions from Bacterial Genomes: Identification of the Sinorhizobium meliloti pExo Megaplasmid Replicator Region

Chain, Patrick S. G., Hernandez-Lucas, Ismael, Golding, Brian, Finan, Turlough M.

We have developed a procedure to directly clone large fragments from the genome of the soil bacterium Sinorhizobium meliloti. Specific regions to be cloned are first flanked by parallel copies of an...

Novel Pathway for Arsenic Detoxification in the Legume Symbiont Sinorhizobium meliloti

Yang, Hung-Chi, Cheng, Jiujun, Finan, Turlough M., Rosen, Barry P., Bhattacharjee, Hiranmoy

We report a novel pathway for arsenic detoxification in the legume symbiont Sinorhizobium meliloti. Although a majority of ars operons consist of three genes, arsR (transcriptional regulator), arsB...

Novel DNA Sequences from Natural Strains of the Nitrogen-Fixing Symbiotic Bacterium Sinorhizobium meliloti†

Guo, Hong, Sun, Sheng, Finan, Turlough M., Xu, Jianping

Variation in genome size and content is common among bacterial strains. Identifying these naturally occurring differences can accelerate our understanding of bacterial attributes, such as ecological...

Regulation and Properties of PstSCAB, a High-Affinity, High-Velocity Phosphate Transport System of Sinorhizobium meliloti

Yuan, Ze-Chun, Zaheer, Rahat, Finan, Turlough M.

The properties and regulation of the pstSCAB-encoded Pi uptake system from the alfalfa symbiont Sinorhizobium meliloti are reported. We present evidence that the pstSCAB genes and the regulatory...

Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria

Yuan, Ze-Chun, Zaheer, Rahat, Morton, Richard, Finan, Turlough M.

In proteobacteria, genes whose expression is modulated in response to the external concentration of inorganic phosphate are often regulated by the PhoB protein which binds to a conserved motif (Pho...

Characterization of the β-Ketoadipate Pathway in Sinorhizobium meliloti

MacLean, Allyson M., MacPherson, Gordon, Aneja, Punita, Finan, Turlough M.

Aromatic compounds represent an important source of energy for soil-dwelling organisms. The β-ketoadipate pathway is a key metabolic pathway involved in the catabolism of the aromatic compounds...

An Integrated Approach to Functional Genomics: Construction of a Novel Reporter Gene Fusion Library for Sinorhizobium meliloti▿ †

Cowie, Alison, Cheng, Jiujun, Sibley, Christopher D., Fong, Ying, Zaheer, Rahat, Patten, Cheryl L., ...

As a means of investigating gene function, we developed a robust transcription fusion reporter vector to measure gene expression in bacteria. The vector, pTH1522, was used to construct a random...

Malic Enzyme Cofactor and Domain Requirements for Symbiotic N2 Fixation by Sinorhizobium meliloti▿ †

Mitsch, Michael J., Cowie, Alison, Finan, Turlough M.

The NAD+-dependent malic enzyme (DME) and the NADP+-dependent malic enzyme (TME) of Sinorhizobium meliloti are representatives of a distinct class of malic enzymes that contain a 440-amino-acid...

Binding Site Determinants for the LysR-Type Transcriptional Regulator PcaQ in the Legume Endosymbiont Sinorhizobium meliloti▿

MacLean, Allyson M., Anstey, Michelle I., Finan, Turlough M.

LysR-type transcriptional regulators represent one of the largest groups of prokaryotic regulators described to date. In the gram-negative legume endosymbiont Sinorhizobium meliloti, enzymes involved...