Ty Arrington

Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes

Shah, Mithun Vinod, Zhang, Ranran, Irby, Rosalyn, Kothapalli, Ravi, Liu, Xin, Arrington, Ty, ...

T-cell large granular lymphocyte (LGL) leukemia is characterized by clonal expansion of CD3+CD8+ cells. Leukemic LGLs correspond to terminally differentiated effector-memory cytotoxic T lymphocytes...