Modulation of Growth Hormone and Prolactin Secretion in Trypanosoma cruzi-Infected Mammosomatotrophic Cells (2009)
Paez-Pereda, M.,
Theodoropoulou, M.,
Renner, U.,
Stalla, J.,
Stalla, G. K.,
...
Intrapituitary Expression and Regulation of the gp130 Cytokine Interleukin-6 and Its Implication in Pituitary Physiology and Pathophysiology (2009)
Renner, U.,
De Santana, E. C.,
Gerez, J.,
Fröhlich, B.,
Haedo, M.,
Paez-Pereda, M.,
...
NOD2 receptors in adenopituitary folliculostellate cells: expression and function (2009)
Fröhlich, B.,
Labeur, M.,
Paez-Pereda, M.,
Theodoropoulou, M.,
Monteserin, J. L.,
...
Regulation of Pituitary Function by Cytokines (2009)
Haedo, M. R.,
Gerez, J.,
Fuertes, M.,
Giacomini, D.,
Paez-Pereda, M.,
Labeur, M.,
...
Stimulation- and palmitoylation-dependent changes in oligomeric conformation of serotonin 5-HT1A receptors. (2008)
Kobe, F.,
Renner, U.,
Woehler, A.,
Wlodarczyk, P.,
Papusheva, E.,
Bao, G.,
...
Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel (2008)
Tichomirowa, M. A.,
Theodoropoulou, M.,
Daly, A. F.,
Yassouridis, A.,
Hansen, S.,
Lu, J.,
...
Localization of the mouse 5-Hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling (2007)
Renner, U.,
Glebov, K.,
Lang, T.,
Papusheva, E.,
Balakrishnan, S.,
Keller, B.,
...
Octreotide inhibits PDGF-induced VEGF secretion in somatotroph MtT/S pituitary cells through interference at the PI3 kinase signalling pathway (2007)
Colaco, T.,
Onoffi, C.,
Theodoropoulou, M.,
Kowarik, M.,
Stalla, G. K.,
Renner, U.
Bacterial muramy dipeptide differently affect IL-6 and VEGF production in pituitary folliculostellate TtT/GF cells through NOD1 and NOD2 receptors (2007)
Onofri, C.,
Labeur, M.,
Theodoropoulou, M.,
Colaco, T.,
Stalla, G. K.,
...
Expression and functionality of NOD molecules in the adenopituitary folliculostellate cells (2007)
Theodoropoulou, M.,
Paez-Pereda, M.,
Onofri, C.,
Labeur, M.,
Renner, U.,
...
Molecular transduction mechanisms of cytokine-hormone interactions: role of gp130 cytokines (2007)
Gerez, J.,
Bonfiglio, J.,
Sosa, S.,
Giacomini, D.,
Acuna, M.,
Nagashima, A. C.,
...
Pituitary action of cytokines: Focus on BMP-4 and gp130 family (2007)
Giacomini, D.,
Acuna, M.,
Gerez, J.,
Nagashima, A. C.,
Silberstein, S.,
Paez-Pereda, M.,
...
Involvement of the calcium-binding protein secretagogin in pituitary adenoma hormone production (2007)
Onofri, C.,
Vila, G.,
Stalla, J.,
Labeur, M.,
Theodoropoulou, M.,
...
Involvement of the calcium-binding protein Secretagogin in pituitary adenoma hormone secretion (2007)
Onofri, C.,
Vila, G.,
Wagner, L.,
Labeur, M.,
Luger, A.,
...
Hypothalamus-pituitary-adrenal axis during Trypanosoma cruzi acute infection in mice (2006)
Paez-Pereda, M.,
Theodoropoulou, M.,
Nihei, O. K.,
Gruebler, Y.,
Bozza, M.,
...
Bone morphogenetic protein-4 control of pituitary pathophysiology (2006)
Giacomini, D.,
Páez-Pereda, M.,
Theodoropoulou, M.,
Gerez, J.,
Nagashima, A. C.,
Chervin, A.,
...
Temazepam triggers the release of vasopressin into the rat hypothalamic paraventricular nucleus: Novel insight into benzodiazepine action on hypothalamic-pituitary-adrenocortical system activity during stress (2006)
Welt, T.,
Engelmann, M.,
Renner, U.,
Erhardt, A.,
Müller, M. B.,
Landgraf, R.,
...
Endocrine disturbances in depression (2005)
Tichomirowa, M. A.,
Keck, M. E.,
Schneider, H. J.,
Paez-Pereda, M.,
Renner, U.,
Holsboer, F.,
...
Bacterial endotoxin (lipopolysaccharide) stimulates interleukin-6 production and inhibits growth of pituitary tumour cells expressing the Toll-like receptor 4 (2005)
Tichomirowa, M.,
Theodoropoulou, M.,
Lohrer, P.,
Schaaf, L.,
Losa, M.,
Uhl, E.,
...
Estradiol Stimulates Vascular Endothelial Growth Factor and Interleukin-6 in Human Lactotroph and Lactosomatotroph Pituitary Adenomas (2004)
Onofri, C.,
Carbia Nagashima, A.,
Schaaf, L.,
Feirer, M.,
Lohrer, P.,
Stummer, W.,
...
Involvement of the gp130 cytokine transducer in MtT/S pituitary somatotroph tumour development in an autocrine-paracrine model (2004)
Graciarena, M.,
Carbia-Nagashima, A.,
Onofri, C.,
Perez-Castro, C.,
Giacomini, D.,
Renner, U.,
...
Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs (2004)
Kovalovsky, D.,
Paez-Pereda, M.,
Labeur, M.,
Renner, U.,
Holsboer, F.,
Stalla, G. K.,
...
Reduced expression of the cytokine transducer gp130 inhibits hormone secretion, cell growth, and tumor development of pituitary lactosomatotrophic GH3 cells (2003)
Castro, CP,
Giacomini, D,
Nagashima, AC,
Onofri, C,
Graciarena, M,
Kobayashi, K,
...
Two of the most potent cytokines that regulate anterior pituitary cell function are leukemia inhibitory factor and IL- 6. These and others like IL-11 and ciliary neurotrophic factor are referred to...
Laminin inhibits lactotroph proliferation and is reduced in early prolactinoma development (2003)
Kuchenbauer, F.,
Theodoropoulou, M.,
Hopfner, U.,
Stalla, J.,
Renner, U.,
Tonn, J. C.,
...
Transcriptional regulation of interleukin-6 in pituitary folliculo-stellate TtT/GF cells (2003)
Nagashima, A. C.,
Giacomini, D.,
Castro, C. P.,
Pereda, M. P.,
Renner, U.,
Stalla, G. K.,
...
Transforming growth factor-β stimulates vascular endothelial growth factor production by folliculostellate pituitary cells (2002)
Renner, U,
Lohrer, P,
Schaaf, L,
Feirer, M,
Schmitt, K,
Onofri, C,
...
TGF-beta isoforms are expressed in the anterior pituitary and modulate the growth and function of endocrine pituitary cells. Recently, TGF-beta has been shown to stimulate growth and basic fibroblast...
The role of endothelins in the regulation of pituitary function (2002)
Lange, M,
Pagotto, U,
Renner, U,
Arzberger, T,
Oeckler, R,
Stalla, GK
The different members of the endothelin peptide family exhibit potent, long-lasting vasoconstrictive effects and thus play a central role in blood pressure regulation. However, endothelins have also...
The intrapituitary stimulatory effect of lipopolysaccharide on ACTH secretion is mediated by paracrine-acting IL-6 (2001)
Gloddek, J,
Lohrer, P,
Stalla, J,
Arzt, E,
Stalla, GK,
Renner, U
During infection/inflammation bacterial lipopolysaccharide (LPS) activates the immune system and thus enhances the level of circulating cytokines. These circulating cytokines induce adaptive...
Expression of CRHR 1 and CRHR 2 in mouse pituitary and adrenal gland: implications for HPA system regulation. (2001)
Müller, M. B.,
Preil, J.,
Renner, U.,
Zimmermann, S.,
Kresse, A. E.,
Stalla, G. K.,
...
The anxiolytic effect of the CRH1 receptor antagonist R121919 depends on innate emotionality in rats. (2001)
Keck, M. E.,
Welt, T.,
Wigger, A.,
Renner, U.,
Engelmann, M.,
Holsboer, F.,
...
The intrapituitary stimulatory effect of lipopolysaccharide on ACTH secretion is mediated by paracrine-acting IL-6. (2001)
Gloddek, J.,
Lohrer, P.,
Stalla, J.,
Arzt, E.,
Stalla, G. K.,
Renner, U.
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro. (2001)
Lohrer, P.,
Gloddek, J.,
Hopfner, U.,
Losa, M.,
Uhl, E.,
Pagotto, U.,
...
High levels of matrix metalloproteinases regulate proliferation and hormone secretion in pituitary cells. (2000)
Paez Pereda, M.,
Ledda, M. F.,
Goldberg, V.,
Chervin, A.,
Carrizo, G.,
Molina, H.,
...
Lipopolysaccharide directly stimulates the intrapituitary interleukin-6 production by folliculostellate cells via specific receptors and the p38α mitogen-activated protein kinase/nuclear factor-κB pathway. (2000)
Lohrer, P.,
Gloddek, J.,
Carbia Nagashima, A.,
Korali, Z.,
Hopfner, U.,
Paez Pereda, M.,
...
Retinoic acid stimulates meningioma cell adhesion to the extracellular matrix and inhibits invasion. (1999)
Paez Pereda, M.,
Hopfner, U.,
Pagotto, U.,
Renner, U.,
Uhl, E.,
Arzt, E.,
...
Physio-pathological role of the cytokine network in the anterior pituitary gland. (1999)
Arzt, E.,
Paez Pereda, M.,
Perez Castro, C.,
Pagotto, U.,
Renner, U.,
Stalla, G. K.
Early activation of the thyrotropin-releasing hormone and prolactin a critical role during a T-cell-dependent immune response. (1999)
Perez Castro, C.,
Peñalva, R.,
Páez Pereda, M.,
Renner, U.,
Stalla, G. K.,
...
Pituitary adenylate cyclase activating polypeptide, interleukin-6, and glucocorticoids regulate the release of vascular endothelial growth factor in pituitary folliculostellate cells. (1999)
Gloddek, J.,
Pagotto, U.,
Paez Pereda, M.,
Arzt, E.,
Stalla, G. K.,
Renner, U.
Interleukin-1ß enhances interleukin-1 receptor antagonist content in human somatotroph adenoma cell cultures. (1998)
Sauer, J.,
Renner, U.,
Hopfner, U.,
Lange, M.,
Strasburger, C.,
Pagotto, U.,
...
Heterogenous dopamine D2 receptor subtype mRNA expression in clinically nonfunctioning pituitary adenomas. (1998)
Renner, U.,
Arzberger, T.,
Pagotto, U.,
Leimgruber, S.,
Uhl, E.,
Müller, A.,
...
Cytokine expression and molecular mechanisms of their autocrine/paracrine regulation of anterior pituitary function and growth. (1998)
Arzt, E.,
Paez Pereda, M.,
Costas, M.,
Sauer, J.,
Renner, U.,
Holsboer, F.,
...
Pure antiestrogens synergise with dopamine agonists to block prolactin synthesis - a potential new strategy for the treatment of prolactinomas (1996)
Newton, C. J.,
Koller, G. K.,
Renner, U.,
Pagotto, U.,
Oertel, H.,
Stalla, G. K.
Characterization and interleukin-2 (IL-2) receptor expression and action of IL-2 and IL-6 on normal anterior pituitary cell growth (1995)
Arzt, E.,
Sauer, J.,
Buric, R.,
Stalla, J.,
Renner, U.,
Stalla, G. K.
Expression and localization of endothelin-1 and endothelin-receptors in human meningeomas: Evidence for a role in tumoral growth (1995)
Pagotto, U.,
Arzberger, T.,
Hopfner, U.,
Sauer, J.,
Renner, U.,
Newton, C. J.,
...
Involvement of interleukin-1 and interleukin-1 receptor antagonist in rat pituitary cell growth regulation (1995)
Renner, U.,
Newton, C. J.,
Pagotto, U.,
Sauer, J.,
Arzt, E.,
Stalla, G. K.
Growth hormone (GH)-releassing peptide stimulation of GH release from human somatotroph adenoma cells: interaction with GH-releasing hormone, thyrotropin-releasing hormone, and octreotide (1994)
Renner, U.,
Brockmeier, S.,
Strasburger, C. J.,
Lange, M.,
Schopohl, J.,
Müller, O. A.,
...
Effect of bromocriptine and SMS 201-995 on growth of human somatotrophic and nonfunctioning pituitary adenoma cells in vitro (1994)
Renner, U.,
Mojito, J.,
Lange, M.,
Werder, K. Von,
Müller, O. A.,
Stalla, G. K.
SMS 201-995 exerts different effects in vivo and in vitro in ACTH dependent Cushing`s syndrome (1994)
Stalla, G. K.,
Brockmeier, S. J.,
Renner, U.,
Newton, C.,
Buchfelder, M.,
Stalla, J.,
...
Interleukin involvement in anterior pituitary cell growth regulation: effects of interleukin-2 and interleukin-6 (1993)
Arzt, E.,
Buric, R.,
Stelzer, G.,
Stalla, J.,
Sauer, J.,
Renner, U.,
...
Polypeptide growth factors are secreted by human nonfunctioning pituitary adenoma cells in culture (1993)
Renner, U.,
Mojto, J.,
Arzt, E.,
Lange, M.,
Stalla, J.,
Müller, O. A.,
...
Abstract (1992)
Strohscheer, I.,
Kleinert, R.,
Westphal, C.,
Schüller, J.,
Werner, K.,
Anders, O.,
...
Peer Reviewed
Floating pulmonary embolus: unusual cause of recurrent syncope (1984)
BUSCH, U.,
RENNER, U.,
WIRTZFELD, A.,
SEBENING, H.,
KLEIN, G.,
HAGL, S.
A 69-year old woman was admitted because of recurrent syncopal episodes. In hospital, she had repeated attacks of near fainting or syncope when she was turned into the left decubitus position....
Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth.
Pagotto, U,
Arzberger, T,
Hopfner, U,
Sauer, J,
Renner, U,
Newton, C J,
...
In addition to its well-known homoeostatic actions in the cardiovascular system, ET-1 has been shown to constitute a potent growth regulatory peptide in various tissues. We have studied the...
Interleukin-2 and interleukin-2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures.
Arzt, E,
Stelzer, G,
Renner, U,
Lange, M,
Müller, O A,
Stalla, G K
The production of IL-1 and IL-6 by pituitary cells has recently been demonstrated. In this study we investigated the expression of IL-2 and its receptor (IL-2R) by pituitary cells of different...
Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth.
Pagotto, U,
Arzberger, T,
Hopfner, U,
Sauer, J,
Renner, U,
Newton, C J,
...
In addition to its well-known homoeostatic actions in the cardiovascular system, ET-1 has been shown to constitute a potent growth regulatory peptide in various tissues. We have studied the...
Interleukin-2 and interleukin-2 receptor expression in human corticotrophic adenoma and murine pituitary cell cultures.
Arzt, E,
Stelzer, G,
Renner, U,
Lange, M,
Müller, O A,
Stalla, G K
The production of IL-1 and IL-6 by pituitary cells has recently been demonstrated. In this study we investigated the expression of IL-2 and its receptor (IL-2R) by pituitary cells of different...
Retinoic acid stimulates meningioma cell adhesion to the extracellular matrix and inhibits invasion
Pereda, M Páez,
Hopfner, U,
Pagotto, U,
Renner, U,
Uhl, E,
Arzt, E,
...
Meningiomas are tumours derived from the arachnoid and pia mater. During embryogenesis, these membranes develop from the migrating craniofacial neural crest. We have previously demonstrated that...