Ulrich Stelzl

An empirical framework for binary interactome mapping (2009)

Venkatesan, Kavitha, Rual, Jean-Francois, Vazquez, Alexei, Stelzl, Ulrich, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, ...

Several attempts have been made to systematically map protein-protein interaction, or 'interactome', networks. However, it remains difficult to assess the quality and coverage of existing data sets....

Characterization of RNA-protein interactions by phosphorothioate footprinting and its applications to the ribosome (2008)

Bishop, A. Özlem Tastan, Stelzl, Ulrich, Pech, Markus, Nierhaus, Knud H.

Analogs of naturally occurring substances obtained by chemical modifications are powerful tools to study intra- and intermolecular interactions. We have used the phosphorothioate technique to analyze...

A human protein-protein interaction network : a resource for annotating the proteome (2005)

Stelzl, Ulrich, Worm, Uwe, Lalowski, Maciej, Haenig, Christian, Brembeck, Felix H., Goehler, Heike, ...

Protein-protein interaction maps provide a valuable framework for a better understanding of the functional organization of the proteome. To detect interacting pairs of human proteins systematically,...

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's Disease (2004)

Goehler,Heike, Lalowski,Maciej, Stelzl,Ulrich, Waelter,Stephanie, Stroedicke,Martin, Worm,Uwe, ...

Analysis of protein-protein interactions (PPIs) is a valuable approach for characterizing proteins of unknown function. Here, we have developed a strategy combining library and matrix yeast...

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's Disease (2004)

Goehler, Heike, Lalowski, Maciej, Stelzl, Ulrich, Waelter, Stephanie, Stroedicke, Martin, Worm, Uwe, ...

Analysis of protein-protein interactions (PPIs) is a valuable approach for characterizing proteins of unknown function. Here, we have developed a strategy combining library and matrix yeast...

RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon (2003)

Stelzl,Ulrich, Zengel,Janice M., Tovbina,Marina, Walker,Marquis, Nierhaus,Knud H., Lindahl,Lasse, ...

Ribosomal protein L4 regulates the 11-gene S10 operon in Escherichia coli by acting, in concert with transcription factor NusA, to cause premature transcription termination at a Rho-independent...

RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon (2003)

Stelzl, Ulrich, Zengel, Janice M., Tovbina, Marina, Walker, Marquis, Nierhaus, Knud H., Lindahl, Lasse, ...

Ribosomal protein L4 regulates the 11-gene S10 operon in Escherichia coli by acting, in concert with transcription factor NusA, to cause premature transcription termination at a Rho-independent...

The tetracycline resistance protein Tet() perturbs the conformation of the ribosomal decoding centre (2002)

Connell,Sean R., Trieber,Catharine A., Stelzl,Ulrich, Einfeldt,Edda, Taylor,Diane E., Nierhaus,Knud H.

Tet() is an elongation factor-like protein found in clinical isolates of Campylobacter jejuni that confers resistance to the protein-synthesis inhibitor tetracycline. Tet() interacts with the 70S...

Protein Synthesis at Atomic Resolution: Mechanistics of Translation in the Light of Highly Resolved Structures for the Ribosome (2002)

Wilson,Daniel N., Blaha,Gregor, Connell,Sean R., Ivanov,Pavel V., Jenke,Holger, Stelzl,Ulrich, ...

Our understanding of the process of translation has progressed rapidly since the availability of highly resolved structures for the ribosome. A wealth of information has emerged in terms of both RNA...

Protein Synthesis at Atomic Resolution: Mechanistics of Translation in the Light of Highly Resolved Structures for the Ribosome (2002)

Wilson, Daniel N., Blaha, Gregor, Connell, Sean R., Ivanov, Pavel V., Jenke, Holger, Stelzl, Ulrich, ...

Our understanding of the process of translation has progressed rapidly since the availability of highly resolved structures for the ribosome. A wealth of information has emerged in terms of both RNA...

The tetracycline resistance protein Tet() perturbs the conformation of the ribosomal decoding centre (2002)

Connell, Sean R., Trieber, Catharine A., Stelzl, Ulrich, Einfeldt, Edda, Taylor, Diane E., Nierhaus, Knud H.

Tet() is an elongation factor-like protein found in clinical isolates of Campylobacter jejuni that confers resistance to the protein-synthesis inhibitor tetracycline. Tet() interacts with the 70S...

Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: Application of a method called SERF

Stelzl, Ulrich, Spahn, Christian M. T., Nierhaus, Knud H.

Two-thirds of the 54 proteins of the Escherichia coli ribosome interact directly with the rRNAs, but the rRNA binding sites of only a very few proteins are known. We present a method (selection of...

Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer

Diedrich, Gundo, Spahn, Christian M.T., Stelzl, Ulrich, Schäfer, Markus A., Wooten, Tammy, Bochkariov, Dmitry E., ...

Ribosomal proteins L2, L3 and L4, together with the 23S RNA, are the main candidates for catalyzing peptide bond formation on the 50S subunit. That L2 is evolutionarily highly conserved led us to...

Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

Blume, Astrid, Weidemann, Wenke, Stelzl, Ulrich, Wanker, Erich E., Lucka, Lothar, Donner, Peter, ...

UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase is a bifunctional enzyme, which initiates and regulates sialic acid biosynthesis. Sialic acids are important compounds of mammalian...

Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: Application of a method called SERF

Stelzl, Ulrich, Spahn, Christian M. T., Nierhaus, Knud H.

Two-thirds of the 54 proteins of the Escherichia coli ribosome interact directly with the rRNAs, but the rRNA binding sites of only a very few proteins are known. We present a method (selection of...

Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer

Diedrich, Gundo, Spahn, Christian M.T., Stelzl, Ulrich, Schäfer, Markus A., Wooten, Tammy, Bochkariov, Dmitry E., ...

Ribosomal proteins L2, L3 and L4, together with the 23S RNA, are the main candidates for catalyzing peptide bond formation on the 50S subunit. That L2 is evolutionarily highly conserved led us to...

Domain-specific characteristics of the bifunctional key enzyme of sialic acid biosynthesis, UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

Blume, Astrid, Weidemann, Wenke, Stelzl, Ulrich, Wanker, Erich E., Lucka, Lothar, Donner, Peter, ...

UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase is a bifunctional enzyme, which initiates and regulates sialic acid biosynthesis. Sialic acids are important compounds of mammalian...

Detection of Alpha-Rod Protein Repeats Using a Neural Network and Application to Huntingtin

Palidwor, Gareth A., Shcherbinin, Sergey, Huska, Matthew R., Rasko, Tamas, Stelzl, Ulrich, Arumughan, Anup, ...

A growing number of solved protein structures display an elongated structural domain, denoted here as alpha-rod, composed of stacked pairs of anti-parallel alpha-helices. Alpha-rods are flexible and...