Colecchia, Federico, Kottwitz, Denise, Wagner, Mandy, Pfenninger, Cosima V., Thiel, Gerald, Tamm, Ingo, ...
The prediction of transcription factor binding sites in genomic sequences is in principle very useful to identify upstream regulatory factors. However, when applying this concept to genomes of...
Transcriptional Dynamics of the Embryonic Stem Cell Switch (2008)
Vijay Chickarmane, Carl Troein, Ulrike A. Nuber, Herbert M. Sauro, Carsten Peterson
Recent ChIP experiments of human and mouse embryonic stem cells have elucidated the architecture of the transcriptional regulatory circuitry responsible for cell determination, which involves the...
Pfenninger, Cosima V, Roschupkina, Teona, Hertwig, Falk, Kottwitz, Denise, Englund, Elisabet, Bengzon, Johan, ...
Abstract is not available
Transcriptional Dynamics of the Embryonic Stem Cell Switch (2006)
Vijay Chickarmane, Carl Troein, Ulrike A. Nuber, Herbert M. Sauro, Carsten Peterson
Recent ChIP experiments of human and mouse embryonic stem cells have elucidated the architecture of the transcriptional regulatory circuitry responsible for cell determination, which involves the...
Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome (2005)
Nuber, Ulrike A., Kriaucionis, Skirmantas, Roloff, Tim C., Guy, Jacky, Selfridge, Jim, Steinhoff, Christine, ...
Rett syndrome (RTT) is a severe form of mental retardation, which is caused by spontaneous mutations in the X-linked gene MECP2. How the loss of MeCP2 function leads to RTT is currently unknown. Mice...
Oostendorp, Robert A.J., Robin, Catherine, Steinhoff, Christine, Marz, Stefanie, Bräuer, Rosalinde, Nuber, Ulrike A., ...
We recently established that two midgestation-derived stromal clones—UG26-1B6, urogenital ridge–derived, and EL08-1D2, embryonic liver–derived—support the maintenance of murine adult bone...
Nino-Soto, M.I., Nuber, Ulrike A., Basrur, P.K., Ropers, Hans-Hilger, King, W.A.
The sex determination system in mammals creates an imbalance between males and females in the number of X chromosomes. This imbalance is compensated through transcriptional silencing of one of the...
Oostendorp, Robert A.J., Robin, Catherine, Steinhoff, Christine, Marz, Stefanie, Braeuer, Rosalinde, Nuber, Ulrike A., ...
We recently established that two midgestation-derived stromal clones—UG26-1B6, urogenital ridge–derived, and EL08-1D2, embryonic liver–derived—support the maintenance of murine adult bone...
Epigenetics, chromatin, and stem cells (2005)
Roloff, Tim C., Nuber, Ulrike A.
Epigenetics is a term that has changed its meaning with the increasing biological knowledge on developmental processes. However, its current application to stem cell biology is often imprecise and is...
Singh, Umashankar, Sun, Tong, Shi, Wei, Schulz, Ralph, Nuber, Ulrike A., Varanou, Aikaterini, ...
Different causes, such as maternal diabetes, cloning by nuclear transfer, interspecific hybridization, and deletion of some genes such as Esx1, Ipl, or Cdkn1c, may underlie placental overgrowth. In a...
Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome (2005)
Nuber, Ulrike A., Kriaucionis, Skirmantas, Roloff, Tim C., Guy, Jacky, Selfridge, Jim, Steinhoff, Christine, ...
Rett syndrome (RTT) is a severe form of mental retardation, which is caused by spontaneous mutations in the X-linked gene MECP2. How the loss of MeCP2 function leads to RTT is currently unknown. Mice...
Oostendorp, Robert A.J., Robin, Catherine, Steinhoff, Christine, Marz, Stefanie, Braeuer, Rosalinde, Nuber, Ulrike A., ...
We recently established that two midgestation-derived stromal clones—UG26-1B6, urogenital ridge–derived, and EL08-1D2, embryonic liver–derived—support the maintenance of murine adult bone...
Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome (2005)
Nuber, Ulrike A., Kriaucionis, Skirmantas, Roloff, Tim C., Guy, Jacky, Selfridge, Jim, Steinhoff, Christine, ...
Rett syndrome (RTT) is a severe form of mental retardation, which is caused by spontaneous mutations in the X-linked gene MECP2. How the loss of MeCP2 function leads to RTT is currently unknown. Mice...
BRCA1-mediated repression of select X chromosome genes (2004)
Jazaeri, Amir A, Chandramouli, Gadisetti VR, Aprelikova, Olga, Nuber, Ulrike A, Sotiriou, Christos, Liu, Edison T, ...
Abstract Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated....
BRCA1-mediated repression of select X chromosome genes (2004)
Jazaeri,Amir A, Chandramouli,Gadisetti VR, Aprelikova,Olga, Nuber,Ulrike A, Sotiriou,Christos, Liu,Edison T, ...
Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated. Complementary...
Gene expression changes in the course of neural progenitor cell differentiation (2004)
Gurok,Ulf, Steinhoff,Christine, Lipkowitz,Bettina, Ropers,Hans-Hilger, Scharff,Constance, Nuber,Ulrike A.
The molecular changes underlying neural progenitor differentiation are essentially unknown. We applied cDNA microarrays with 13,627 clones to measure dynamic gene expression changes during the in...
Gene expression changes in the course of neural progenitor cell differentiation (2004)
Gurok,Ulf, Steinhoff,Christine, Lipkowitz,Bettina, Ropers,Hans-Hilger, Scharff,Constance, Nuber,Ulrike A.
The molecular changes underlying neural progenitor differentiation are essentially unknown. We applied cDNA microarrays with 13,627 clones to measure dynamic gene expression changes during the in...
Singh,Umashankar, Fohn,Laurel E., Wakayama,Teruhiko, Ohgane,Jun, Steinhoff,Christine, Lipkowitz,Bettina, ...
To obtain a deeper insight into the genes and gene networks involved in the development of placentopathies, we have assessed global gene expression in three different models of placental hyperplasia...
Singh,Umashankar, Fohn,Laurel E., Wakayama,Teruhiko, Ohgane,Jun, Steinhoff,Christine, Lipkowitz,Bettina, ...
To obtain a deeper insight into the genes and gene networks involved in the development of placentopathies, we have assessed global gene expression in three different models of placental hyperplasia...
Dyschromatosis universalis hereditaria: Familial case and ultrastructural skin investigation (2004)
Nuber,Ulrike A., Tinschert,Sigrid, Mundlos,Stefan, Hausser,Ingrid
We report a familial case of dyschromatosis universalis hereditaria (DUH) which is compatible with an autosomal dominant inheritance. The male proband from Bangladesh presented with randomly...
Dyschromatosis universalis hereditaria: Familial case and ultrastructural skin investigation (2004)
Nuber,Ulrike A., Tinschert,Sigrid, Mundlos,Stefan, Hauber,Ingrid
We report a familial case of dyschromatosis universalis hereditaria (DUH) which is compatible with an autosomal dominant inheritance. The male proband from Bangladesh presented with randomly...
Dyschromatosis universalis hereditaria: Familial case and ultrastructural skin investigation (2004)
Nuber,Ulrike A., Tinschert,Sigrid, Mundlos,Stefan, Hauber,Ingrid
We report a familial case of dyschromatosis universalis hereditaria (DUH) which is compatible with an autosomal dominant inheritance. The male proband from Bangladesh presented with randomly...
Dyschromatosis universalis hereditaria: Familial case and ultrastructural skin investigation (2004)
Nuber, Ulrike A., Tinschert, Sigrid, Mundlos, Stefan, Hausser, Ingrid
We report a familial case of dyschromatosis universalis hereditaria (DUH) which is compatible with an autosomal dominant inheritance. The male proband from Bangladesh presented with randomly...
Gene expression changes in the course of neural progenitor cell differentiation (2004)
Gurok, Ulf, Steinhoff, Christine, Lipkowitz, Bettina, Ropers, Hans-Hilger, Scharff, Constance, Nuber, Ulrike A.
The molecular changes underlying neural progenitor differentiation are essentially unknown. We applied cDNA microarrays with 13,627 clones to measure dynamic gene expression changes during the in...
BRCA1-mediated repression of select X chromosome genes (2004)
Jazaeri, Amir A, Chandramouli, Gadisetti VR, Aprelikova, Olga, Nuber, Ulrike A, Sotiriou, Christos, Liu, Edison T, ...
Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated. Complementary...
Dyschromatosis universalis hereditaria: Familial case and ultrastructural skin investigation (2004)
Nuber, Ulrike A., Tinschert, Sigrid, Mundlos, Stefan, Hauber, Ingrid
We report a familial case of dyschromatosis universalis hereditaria (DUH) which is compatible with an autosomal dominant inheritance. The male proband from Bangladesh presented with randomly...
Singh, Umashankar, Fohn, Laurel E., Wakayama, Teruhiko, Ohgane, Jun, Steinhoff, Christine, Lipkowitz, Bettina, ...
To obtain a deeper insight into the genes and gene networks involved in the development of placentopathies, we have assessed global gene expression in three different models of placental hyperplasia...
Dyschromatosis universalis hereditaria: Familial case and ultrastructural skin investigation (2004)
Nuber, Ulrike A., Tinschert, Sigrid, Mundlos, Stefan, Hauber, Ingrid
We report a familial case of dyschromatosis universalis hereditaria (DUH) which is compatible with an autosomal dominant inheritance. The male proband from Bangladesh presented with randomly...
Singh, Umashankar, Fohn, Laurel E., Wakayama, Teruhiko, Ohgane, Jun, Steinhoff, Christine, Lipkowitz, Bettina, ...
To obtain a deeper insight into the genes and gene networks involved in the development of placentopathies, we have assessed global gene expression in three different models of placental hyperplasia...
Gene expression changes in the course of neural progenitor cell differentiation (2004)
Gurok, Ulf, Steinhoff, Christine, Lipkowitz, Bettina, Ropers, Hans-Hilger, Scharff, Constance, Nuber, Ulrike A.
The molecular changes underlying neural progenitor differentiation are essentially unknown. We applied cDNA microarrays with 13,627 clones to measure dynamic gene expression changes during the in...
Expression of mouse Tbx22 supports its role in palatogenesis and glossogenesis (2003)
Herr,Alexander, Meunier,Dominique, Muller,Ines, Rump,Andreas, Fundele,Reinald, Ropers,Hans-Hilger, ...
TBX22 belongs to the T-box family of transcription factors and was originally found in an in silico approach designed to identify new genes on the human Xq12-q21 region. Mutations in TBX22 have been...
Wieczorek,Georg, Steinhoff,Christine, Schulz,Ralph, Scheller,Marina, Vingron,Martin, Ropers,Hans-Hilger, ...
Bone marrow stromal cells (BMSC) have gained increased attention because of their multipotency and adult stem cell character. They have been shown to differentiate into other cell types of the...
Comparative study of methyl-CpG-binding domain proteins (2003)
Roloff, Tim C, Ropers, H Hilger, Nuber, Ulrike A
Abstract Background Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG-binding domain (MBD)...
Comparative study of methyl-CpG-binding domain proteins (2003)
Roloff,Tim-Christoph, Ropers,Hans-Hilger, Nuber,Ulrike A.
Background Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG-binding domain (MBD) can bind to...
Gaussian mixture density estimation applied to microarray data (2003)
Steinhoff,Christine, Müller,Tobias, Nuber,Ulrike A., Vingron,Martin
Several publications have focused on fitting a specific distribution to overall microarray data. Due to a number of biological features the distribution of overall spot intensities can take various...
Expression of mouse Tbx22 supports its role in palatogenesis and glossogenesis (2003)
Herr, Alexander, Meunier, Dominique, Muller, Ines, Rump, Andreas, Fundele, Reinald, Ropers, Hans-Hilger, ...
TBX22 belongs to the T-box family of transcription factors and was originally found in an in silico approach designed to identify new genes on the human Xq12-q21 region. Mutations in TBX22 have been...
Comparative study of methyl-CpG-binding domain proteins (2003)
Roloff, Tim-Christoph, Ropers, Hans-Hilger, Nuber, Ulrike A.
Background Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG-binding domain (MBD) can bind to...
Wieczorek, Georg, Steinhoff, Christine, Schulz, Ralph, Scheller, Marina, Vingron, Martin, Ropers, Hans-Hilger, ...
Bone marrow stromal cells (BMSC) have gained increased attention because of their multipotency and adult stem cell character. They have been shown to differentiate into other cell types of the...
Gaussian mixture density estimation applied to microarray data (2003)
Steinhoff, Christine, Müller, Tobias, Nuber, Ulrike A., Vingron, Martin
Several publications have focused on fitting a specific distribution to overall microarray data. Due to a number of biological features the distribution of overall spot intensities can take various...
Lenzner,Steffen, Prietz,Sandra, Feil,Silke, Nuber,Ulrike A., Ropers,Hans Hilger, Berger,Wolfgang
PURPOSE. Mutations in the NDP gene give rise to a variety of eye diseases, including classic Norrie disease (ND), X-linked exudative vitreoretinopathy (EVRX), retinal telangiectasis (Coats disease),...
Lenzner, Steffen, Prietz, Sandra, Feil, Silke, Nuber, Ulrike A., Ropers, Hans Hilger, Berger, Wolfgang
PURPOSE. Mutations in the NDP gene give rise to a variety of eye diseases, including classic Norrie disease (ND), X-linked exudative vitreoretinopathy (EVRX), retinal telangiectasis (Coats disease),...
Sudbrak, Ralf, Wieczorek, Georg, Nuber, Ulrike A., Mann, Wolfgang, Kirchner, Roland, Erdogan, Fikret, ...
Mutant alleles are frequently characterized by low expression levels. Therefore, cDNA array-based gene expression profiling may be a promising strategy for identifying gene defects underlying...
Erdogan, Fikret, Kirchner, Roland, Mann, Wolfgang, Ropers, Hans-Hilger, Nuber, Ulrike A.
We have developed a novel allele-specific primer elongation protocol using a DNA polymerase on oligonucleotide chips. Oligonucleotide primers carrying polymorphic sites at their free 3'end were...
Expression der Gene der Desmocollin-Familie in menschlichen Zellen und Geweben / (1996)
Heidelberg, Univ., Diss., 1998 (Nicht für den Austausch).
Erdogan, Fikret, Kirchner, Roland, Mann, Wolfgang, Ropers, Hans-Hilger, Nuber, Ulrike A.
We have developed a novel allele-specific primer elongation protocol using a DNA polymerase on oligonucleotide chips. Oligonucleotide primers carrying polymorphic sites at their free 3́end were...
BRCA1-mediated repression of select X chromosome genes
Jazaeri, Amir A, Chandramouli, Gadisetti VR, Aprelikova, Olga, Nuber, Ulrike A, Sotiriou, Christos, Liu, Edison T, ...
Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated. Complementary...
Transcriptional Dynamics of the Embryonic Stem Cell Switch
Chickarmane, Vijay, Troein, Carl, Nuber, Ulrike A, Sauro, Herbert M, Peterson, Carsten
Recent ChIP experiments of human and mouse embryonic stem cells have elucidated the architecture of the transcriptional regulatory circuitry responsible for cell determination, which involves the...
Erdogan, Fikret, Kirchner, Roland, Mann, Wolfgang, Ropers, Hans-Hilger, Nuber, Ulrike A.
We have developed a novel allele-specific primer elongation protocol using a DNA polymerase on oligonucleotide chips. Oligonucleotide primers carrying polymorphic sites at their free 3́end were...
BRCA1-mediated repression of select X chromosome genes
Jazaeri, Amir A, Chandramouli, Gadisetti VR, Aprelikova, Olga, Nuber, Ulrike A, Sotiriou, Christos, Liu, Edison T, ...
Recently BRCA1 has been implicated in the regulation of gene expression from the X chromosome. In this study the influence of BRCA1 on expression of X chromosome genes was investigated. Complementary...
Transcriptional Dynamics of the Embryonic Stem Cell Switch
Chickarmane, Vijay, Troein, Carl, Nuber, Ulrike A, Sauro, Herbert M, Peterson, Carsten
Recent ChIP experiments of human and mouse embryonic stem cells have elucidated the architecture of the transcriptional regulatory circuitry responsible for cell determination, which involves the...
Colecchia, Federico, Kottwitz, Denise, Wagner, Mandy, Pfenninger, Cosima V., Thiel, Gerald, Tamm, Ingo, ...
The prediction of transcription factor binding sites in genomic sequences is in principle very useful to identify upstream regulatory factors. However, when applying this concept to genomes of...