Sahin, Özgür, Fröhlich, Holger, Löbke, Christian, Korf, Ulrike, Burmester, Sara, Majety, Meher, ...
Abstract Background In breast cancer, overexpression of the transmembrane tyrosine kinase ERBB2 is an adverse prognostic marker, and occurs in almost 30% of the patients. For therapeutic...
Automated production of recombinant human proteins as resource for proteome research (2008)
Kohl, Thorsten, Schmidt, Christian, Wiemann, Stefan, Poustka, Annemarie, Korf, Ulrike
Abstract Background An arbitrary set of 96 human proteins was selected and tested to set-up a fully automated protein production strategy, covering all steps from DNA preparation to protein...
From ORFeome to Biology: A Functional Genomics Pipeline (2004)
Wiemann, Stefan, Arlt, Dorit, Huber, Wolfgang, Wellenreuther, Ruth, Schleeger, Simone, Mehrle, Alexander, ...
As several model genomes have been sequenced, the elucidation of protein function is the next challenge toward the understanding of biological processes in health and disease. We have generated a...
From ORFeome to Biology: A Functional Genomics Pipeline
Wiemann, Stefan, Arlt, Dorit, Huber, Wolfgang, Wellenreuther, Ruth, Schleeger, Simone, Mehrle, Alexander, ...
As several model genomes have been sequenced, the elucidation of protein function is the next challenge toward the understanding of biological processes in health and disease. We have generated a...
From ORFeome to Biology: A Functional Genomics Pipeline
Wiemann, Stefan, Arlt, Dorit, Huber, Wolfgang, Wellenreuther, Ruth, Schleeger, Simone, Mehrle, Alexander, ...
As several model genomes have been sequenced, the elucidation of protein function is the next challenge toward the understanding of biological processes in health and disease. We have generated a...
Combinatorial RNAi for quantitative protein network analysis
Sahin, Özgür, Löbke, Christian, Korf, Ulrike, Appelhans, Heribert, Sültmann, Holger, Poustka, Annemarie, ...
The elucidation of cross-talk events between intersecting signaling pathways is one main challenge in biological research. The complexity of protein networks, composed of different pathways, requires...