Urban Deutsch

Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice

Schlaeger, Thorsten M., Bartunkova, Sona, Lawitts, Joel A., Teichmann, Gunnar, Risau, Werner, Deutsch, Urban, ...

TIE2 is a vascular endothelial-specific receptor tyrosine kinase essential for the regulation of vascular network formation and remodeling. Previously, we have shown that the 1.2-kb 5′ flanking...

Regulation of endothelial monocyte-activating polypeptide II release by apoptosis

Knies, Ulrike E., Behrensdorf, Heike A., Mitchell, Christopher A., Deutsch, Urban, Risau, Werner, Drexler, Hannes C. A., ...

Endothelial monocyte-activating polypeptide II (EMAP II) is a proinflammatory cytokine and a chemoattractant for monocytes. We show here that, in the mouse embryo, EMAP II mRNA was most abundant at...

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

Nawroth, Roman, Poell, Gregor, Ranft, Alexander, Kloep, Stephan, Samulowitz, Ulrike, Fachinger, Gregor, ...

VE-cadherin is the essential adhesion molecule in endothelial adherens junctions, and the regulation of protein tyrosine phosphorylation is thought to be important for the control of adherens...

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

Adams, Ralf H., Wilkinson, George A., Weiss, Cornelia, Diella, Francesca, Gale, Nicholas W., Deutsch, Urban, ...

Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate axon guidance and bundling in the developing brain, control cell migration and adhesion, and help patterning...

Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice

Schlaeger, Thorsten M., Bartunkova, Sona, Lawitts, Joel A., Teichmann, Gunnar, Risau, Werner, Deutsch, Urban, ...

TIE2 is a vascular endothelial-specific receptor tyrosine kinase essential for the regulation of vascular network formation and remodeling. Previously, we have shown that the 1.2-kb 5′ flanking...

Regulation of endothelial monocyte-activating polypeptide II release by apoptosis

Knies, Ulrike E., Behrensdorf, Heike A., Mitchell, Christopher A., Deutsch, Urban, Risau, Werner, Drexler, Hannes C. A., ...

Endothelial monocyte-activating polypeptide II (EMAP II) is a proinflammatory cytokine and a chemoattractant for monocytes. We show here that, in the mouse embryo, EMAP II mRNA was most abundant at...

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

Nawroth, Roman, Poell, Gregor, Ranft, Alexander, Kloep, Stephan, Samulowitz, Ulrike, Fachinger, Gregor, ...

VE-cadherin is the essential adhesion molecule in endothelial adherens junctions, and the regulation of protein tyrosine phosphorylation is thought to be important for the control of adherens...

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

Adams, Ralf H., Wilkinson, George A., Weiss, Cornelia, Diella, Francesca, Gale, Nicholas W., Deutsch, Urban, ...

Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate axon guidance and bundling in the developing brain, control cell migration and adhesion, and help patterning...

Regulation of Endothelial Cell Cytoskeletal Reorganization by a Secreted Frizzled-Related Protein-1 and Frizzled 4- and Frizzled 7-Dependent Pathway : Role in Neovessel Formation

Dufourcq, Pascale, Leroux, Lionel, Ezan, Jérome, Descamps, Betty, Lamazière, Jean-Marie Daniel, Costet, Pierre, ...

Consistent with findings of Wnt pathway members involved in vascular cells, a role for Wnt/Frizzled signaling has recently emerged in vascular cell development. Among the few Wnt family members...

Pericyte Migration: A Novel Mechanism of Pericyte Loss in Experimental Diabetic Retinopathy

Pfister, Frederick, Feng, Yuxi, Vom Hagen, Franziska, Hoffmann, Sigrid, Molema, Grietje, Hillebrands, Jan-Luuk, ...

OBJECTIVE— The mechanism underlying pericyte loss during incipient diabetic retinopathy remains controversial. Hyperglycemia induces angiopoietin-2 (Ang-2) transcription, which modulates capillary...

VE-PTP controls blood vessel development by balancing Tie-2 activity

Winderlich, Mark, Keller, Linda, Cagna, Giuseppe, Broermann, Andre, Kamenyeva, Olena, Kiefer, Friedemann, ...

Vascular endothelial protein tyrosine phosphatase (VE-PTP) is an endothelial-specific receptor-type tyrosine phosphatase that associates with Tie-2 and VE-cadherin. VE-PTP gene disruption leads to...