Ursula Ackermann-Liebrich

Circulating alpha1-antitrypsin in the general population: Determinants and association with lung function (2008)

Senn, Oliver, Russi, Erich W, Schindler, Christian, Imboden, Medea, Von Eckardstein, Arnold, Brändli, Otto, ...

Abstract Background Severe alpha1-antitrypsin (AAT) deficiency associated with low AAT blood concentrations is an established genetic COPD risk factor. Less is known about the respiratory health...

Comparing a disease-specific and a generic health-related quality of life instrument in subjects with asthma from the general population (2008)

Puhan, Milo A, Gaspoz, Jean-Michel, Bridevaux, Pierre-Olivier, Schindler, Christian, Ackermann-Liebrich, Ursula, Rochat, Thierry, ...

Abstract Background Few epidemiologic studies have assessed health-related quality of life (HRQL) of asthma patients from a general population and it is unclear which instrument is best suitable for...

Effects of passive smoking on heart rate variability, heart rate and blood pressure: an observational study (2007)

Dietrich, Denise Felber, Schwartz, Joel, Schindler, Christian, Gaspoz, Jean-Michel, Barthélémy, Jean-Claude, Tschopp, Jean-Marie, ...

Background Exposure to environmental tobacco smoke (ETS) has been shown to increase the risk for cardiovascular diseases and death, and autonomic dysfunction (specifically, reduced heart rate...

Annoyance due to air pollution in Europe (2007)

Jacquemin, Bénédicte, Sunyer, Jordi, Forsberg, Bertil, Götschi, Thomas, Bayer-Oglesby, Lucy, Ackermann-Liebrich, Ursula, ...

Background Annoyance due to air pollution is a subjective score of air quality, which has been incorporated into the National Environmental monitoring of some countries. The objectives of this study...

Glutathione S-transferase genotypes modify lung function decline in the general population: SAPALDIA cohort study (2007)

Imboden, Medea, Downs, Sara H, Senn, Oliver, Matyas, Gabor, Brändli, Otto, Russi, Erich W, ...

Abstract Background Understanding the environmental and genetic risk factors of accelerated lung function decline in the general population is a first step in a prevention strategy against the...

Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study (2006)

Nitsch, Dorothea, Dietrich, Denise Felber, Eckardstein, Arnold Von, Gaspoz, Jean-Michel, Downs, Sara H., Leuenberger, Philippe, ...

Background. Impaired renal function is evolving as an independent marker of the risk of cardiovascular morbidity and mortality. Little is known about the prevalence of impaired renal function and its...

Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study (2006)

Nitsch, Dorothea, Dietrich, Denise Felber, Von Eckardstein, Arnold, Gaspoz, Jean-Michel, Downs, Sara H., Leuenberger, Philippe, ...

Background. Impaired renal function is evolving as an independent marker of the risk of cardiovascular morbidity and mortality. Little is known about the prevalence of impaired renal function and its...

Living near Main Streets and Respiratory Symptoms in Adults: The Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (2006)

Bayer-Oglesby, Lucy, Schindler, Christian, Braun-Fahrländer, Charlotte, Keidel, Dirk, Rapp, Regula, ...

The Swiss Cohort Study on Air Pollution and Lung Diseases in Adults (SAPALDIA), conducted in 1991 (SAPALDIA 1) in eight areas among 9,651 randomly selected adults aged 18–60 years, reported...

Heart rate variability in an ageing population and its association with lifestyle and cardiovascular risk factors: results of the SAPALDIA study (2006)

Felber Dietrich, Denise, Schindler, Christian, Schwartz, Joel, Barthélémy, Jean-Claude, Tschopp, Jean-Marie, Roche, Frédéric, ...

Aims (i) To report associations between cardiovascular risk factors and heart rate variability (HRV) in a general population and (ii) to provide normal values for various HRV measurements in a...

Prevalence of renal impairment and its association with cardiovascular risk factors in a general population: results of the Swiss SAPALDIA study (2006)

Nitsch, Dorothea, Dietrich, Denise Felber, Eckardstein, Arnold Von, Gaspoz, Jean-Michel, Downs, Sara H., Leuenberger, Philippe, ...

Background. Impaired renal function is evolving as an independent marker of the risk of cardiovascular morbidity and mortality. Little is known about the prevalence of impaired renal function and its...

Reference values for methacholine reactivity (SAPALDIA study) (2005)

Jayet, Pierre-Yves, Schindler, Christian, Künzli, Nino, Zellweger, Jean-Pierre, Brändli, Otto, Perruchoud, André, ...

Abstract Background The distribution of airway responsiveness in a general population of non-smokers without respiratory symptoms has not been established, limiting its use in clinical and...

Change in prevalence of IgE sensitization and mean total IgE with age and cohort (2005)

Jarvis, Deborah, Luczynska, Christina, Chinn, Susan, Potts, James, Sunyer, Jordi, Janson, Christer, ...

BACKGROUND: Cross-sectional studies show that the prevalence of IgE sensitization is lower in older age groups than younger age groups. This could reflect either a decrease in sensitization with...

Accelerated decline in lung function in smoking women with airway obstruction: SAPALDIA 2 cohort study (2005)

Downs, Sara H, Brändli, Otto, Zellweger, Jean-Pierre, Schindler, Christian, Künzli, Nino, Gerbase, Margaret W, ...

Abstract Background The aim was to determine if effects from smoking on lung function measured over 11 years differ between men and women. Methods In a prospective population based cohort study...

Smoking cessation, lung function, and weight gain: a follow-up study (2005)

Chinn, Susan, Jarvis, Deborah, Melotti, Roberto, Luczynska, Christina, Ackermann-Liebrich, Ursula, Antó, Josep M, ...

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Validity of Annoyance Scores for Estimation of Long Term Air Pollution Exposure in Epidemiologic Studies : The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) (2000)

Oglesby, Lucy, Künzli, Nino, Monn, Christian, Schindler, Christian, Ackermann-Liebrich, Ursula, Leuenberger, Philippe, ...

In air pollution epidemiology, estimates of long term exposure are often based on measurements made at one fixed site monitor per area. This may lead to exposure misclassification. The present paper...

Use of Transition Probabilities to Estimate the Effect of Smoking on the Duration of Episodes of Respiratory Symptoms in Diary Data: The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) (1998)

Kaiser, Reinhard, Schindler, Christian, Künzli, Nino, Ackermann-Liebrich, Ursula, Heeb, Dominik, Medici, Tullio C., ...

Incompletely documented symptom episodes pose methodological problems in the analysis of diary data. The aim of this study was to develop a method of estimating the average durations of symptomatic...

Respiratory Effects of Environmental Tobacco Exposure Are Enhanced by Bronchial Hyperreactivity

Gerbase, Margaret W., Schindler, Christian, Zellweger, Jean-Pierre, Künzli, Nino, Downs, Sara H., Brändli, Otto, ...

Rationale: Exposure to environmental tobacco smoke (ETS) is associated with increased reports of respiratory symptoms and reduced lung function, but the long-term effects of ETS are unclear, notably...