Uwe Scherf

Detailed DNA methylation profiles of the E-cadherin promoter in the NCI-60 cancer cells (2007)

Reinhold, William C., Reimers, Mark A., Maunakea, Alika K., Kim, Sohyoung, Lababidi, Samir, Scherf, Uwe, ...

E-cadherin (E-cad) is a transmembrane adhesion glycoprotein, the expression of which is often reduced in invasive or metastatic tumors. To assess E-cad's distribution among different types of cancer...

Cross-platform comparability of microarray technology: Intra-platform consistency and appropriate data analysis procedures are essential (2005)

Shi, Leming, Tong, Weida, Fang, Hong, Scherf, Uwe, Han, Jing, Puri, Raj K, ...

Abstract Background The acceptance of microarray technology in regulatory decision-making is being challenged by the existence of various platforms and data analysis methods. A recent report (E....

Exploration, Normalization, and Summaries of High Density (2003)

Oligonucleotide Array Probe, Rafael A. Irizarry, Bridget Hobbs, Francois Collin, Kristen J. Antonellis, ...

In this paper we report exploratory analyses of high-density oligonucleotide array data from the Affymetrix system with the objective of improving upon currently used measures of gene expression.

Exploration, normalization, and summaries of high density oligonucleotide array probe level data (2003)

Irizarry, Rafael A., Hobbs, Bridget, Collin, Francois, Beazer-Barclay, Yasmin D., Antonellis, Kristen J., Scherf, Uwe, ...

In this paper we report exploratory analyses of high‐density oligonucleotide array data from the Affymetrix GeneChip® system with the objective of improving upon currently used measures of...

Chemosensitivity prediction by transcriptional profiling

Staunton, Jane E., Slonim, Donna K., Coller, Hilary A., Tamayo, Pablo, Angelo, Michael J., Park, Johnny, ...

In an effort to develop a genomics-based approach to the prediction of drug response, we have developed an algorithm for classification of cell line chemosensitivity based on gene expression profiles...

Chemosensitivity prediction by transcriptional profiling

Staunton, Jane E., Slonim, Donna K., Coller, Hilary A., Tamayo, Pablo, Angelo, Michael J., Park, Johnny, ...

In an effort to develop a genomics-based approach to the prediction of drug response, we have developed an algorithm for classification of cell line chemosensitivity based on gene expression profiles...

MedMiner: An Internet Tool for Filtering and Organizing Biomedical Information

Uwe Scherf, Lawrence. H. Smith, Jae K. Lee, George S, George S. Michaels, Lawrence Hunter, ...

The trend toward high throughput techniques in molecular biology and the explosion of online scientific data threaten to overwhelm the ability of researchers to take full advantage of available...